Nevenka Dimirova - Pelham Manor NY, US Yee Him Cheung - New York NY, US
Assignee:
Koninklijke Philips Electronics N.V. - Eindhoven
International Classification:
G06K 9/00
US Classification:
382129, 382128
Abstract:
Systems and methods facilitate the location and/or identification of repetitive DNA patterns, such as CpG islands, Alu repeats, tandem repeats and various types of satellite repeats. These repetitive elements can be found within a chromosome, within a genome or across genomes of various species. The systems and methods apply image processing operators to find prominent features in the vertical and horizontal direction of the DNA spectrograms. The systems and methods for detecting and/or classifying repetitive DNA patterns include: (a) a comparative histogram method, (b) feature selection and classification using support vector machines and genetic algorithms, and (c) generation of a spectrovideo from a plurality of spectral images.
Methods And Systems To Generate Noncoding-Coding Gene Co-Expression Networks
- EINDHOVEN, NL NEVENKA DIMITROVA - PELHAM MANOR NY, US SONIA CHOTHANI - EINDHOVEN, NL WILHELMUS FRANCISCUS JOHANNES VERHAEGH - EINDHOVEN, NL YEE HIM CHEUNG - NEW YORK NY, US
International Classification:
G06F 19/20 G06F 19/12 C12Q 1/68 G06F 19/18
Abstract:
A method of identifying co-expressed coding and noncoding genes is disclosed. The method may include receiving genetic sequences, mapping the genetic sequences to known coding and noncoding genes, correlating the mapped genes, and generating a co-expression network. A system for generating a co-expression network and providing the co-expression network to a user on a display is disclosed. The system may include a memory, one or more processors, one or more databases, and a display.