Yi Chen - San Mateo CA, US Timothy D. Cushing - Pacifica CA, US Xiaolin Hao - Foster City CA, US Xiao He - Foster City CA, US Andreas Reichelt - Moorpark CA, US Robert M. Rzasa - Ventura CA, US Jennifer Seganish - Garwood NJ, US Youngsook Shin - Emeryville CA, US Dawei Zhang - Thousand Oaks CA, US
Assignee:
Amgen Inc. - Thousand Oaks CA
International Classification:
A61K 31/47
US Classification:
514314, 544333, 546167
Abstract:
Substituted bicyclic heteroaryls having the general formula.
Substituted Pyrazolo[3,4-D]Pyrimidines As Pi3K Inhibitors
Yi Chen - San Mateo CA, US Timothy D. Cushing - Pacifica CA, US Xiaolin Hao - Foster City CA, US Xiao He - Foster City CA, US Andreas Reichelt - Moorpark CA, US Robert M. Rzasa - Ventura CA, US Jennifer Seganish - Garwood NJ, US Youngsook Shin - Emeryville CA, US Dawei Zhang - Thousand Oaks CA, US
Assignee:
Amgen Inc. - Thousand Oaks CA
International Classification:
C07D 487/04 A61K 31/519 A61P 19/02 A61P 29/00
US Classification:
5142621, 544262, 544280, 5142651
Abstract:
Substituted bicyclic heteroaryls and compositions containing them, for the treatment of general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, including but not restricted to autoimmune diseases such as systemic lupus erythematosis (SLE), myestenia gravis, rheumatoid arthritis, acute disseminated encephalomyelitis, idiopathic thrombocytopenic purpura, multiples sclerosis, Sjoegren's syndrome and autoimmune hemolytic anemia, allergic conditions including all forms of hypersensitivity, The present invention also enables methods for treating cancers that are mediated, dependent on or associated with p110δ activity, including but not restricted to leukemias, such as Acute Myeloid leukemia (AML) Myelodysplastic syndrome (MDS) myelo-proliferative diseases (MPD) Chronic Myeloid Leukemia (CML) T-cell Acute Lymphoblastic leukaemia (T-ALL) B-cell Acute Lymphoblastic leukaemia (B-ALL) Non Hodgkins Lymphoma (NHL) B-cell lymphoma and solid tumors, such as breast cancer.
Yi Chen - San Mateo CA, US Timothy D. Cushing - Pacifica CA, US Xiaolin Hao - Foster City CA, US Xiao He - Foster City CA, US Andreas Reichelt - Moorpark CA, US Robert M. Rzasa - Ventura CA, US Jennifer Seganish - Scotch Plains NJ, US Youngsook Shin - Emeryville CA, US Dawei Zhang - Thousand Oaks CA, US
Assignee:
Amgen Inc. - Thousand Oaks CA
International Classification:
A61K 31/47
US Classification:
514314
Abstract:
Substituted bicyclic heteroaryls and compositions containing them, for the treatment of general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, including but not restricted to autoimmune diseases such as systemic lupus erythematosis (SLE), myestenia gravis, rheumatoid arthritis, acute disseminated encephalomyelitis, idiopathic thrombocytopenic purpura, multiples sclerosis, Sjoegren's syndrome and autoimmune hemolytic anemia, allergic conditions including all forms of hypersensitivity. The present invention also enables methods for treating cancers that are mediated, dependent on or associated with p110δ activity, including but not restricted to leukemias, such as Acute Myeloid leukaemia (AML) Myelo-dysplastic syndrome (MDS) myelo-proliferative diseases (MPD) Chronic Myeloid Leukemia (CML) T-cell Acute Lymphoblastic leukaemia (T-ALL) B-cell Acute Lymphoblastic leukaemia (B-ALL) Non Hodgkins Lymphoma (NHL) B-cell lymphoma and solid tumors, such as breast cancer.
Yi Chen - San Mateo CA, US Timothy D. Cushing - Pacifica CA, US Xiaolin Hao - Foster City CA, US Xiao He - Foster City CA, US Andreas Reichelt - Moorpark CA, US Robert M. Rzasa - Ventura CA, US Jennifer Seganish - Scotch Plains NJ, US Youngsook Shin - Emeryville CA, US Dawei Zhang - Thousand Oaks CA, US
Assignee:
Amgen Inc. - Thousand Oaks CA
International Classification:
A61K 31/47
US Classification:
514314
Abstract:
Substituted bicyclic heteroaryls and compositions containing them, for the treatment of general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, including but not restricted to autoimmune diseases such as systemic lupus erythematosis (SLE), myestenia gravis, rheumatoid arthritis, acute disseminated encephalomyelitis, idiopathic thrombocytopenic purpura, multiples sclerosis, Sjoegren's syndrome and autoimmune hemolytic anemia, allergic conditions including all forms of hypersensitivity, The present invention also enables methods for treating cancers that are mediated, dependent on or associated with p110δ activity, including but not restricted to leukemias, such as Acute Myeloid leukaemia (AML) Myelo-dysplastic syndrome (MDS) myelo-proliferative diseases (MPD) Chronic Myeloid Leukemia (CML) T-cell Acute Lymphoblastic leukaemia (T-ALL) B-cell Acute Lymphoblastic leukaemia (B-ALL) Non Hodgkins Lymphoma (NHL) B-cell lymphoma and solid tumors, such as breast cancer.
Yi Chen - San Mateo CA, US Timothy D. Cushing - Pacifica CA, US Jason A. Duquette - Millbrae CA, US Felix Gonzalez Lopez De Turiso - San Mateo CA, US Xiaolin Hao - Foster City CA, US Xiao He - Foster City CA, US Brian Lucas - San Francisco CA, US Lawrence R. McGee - Pacifica CA, US Andreas Reichelt - Moorpark CA, US Robert M. Rzasa - Ventura CA, US Jennifer Seganish - Garwood NJ, US Youngsook Shin - Emeryville CA, US Dawei Zhang - Thousand Oaks CA, US
Yi Chen - San Mateo CA, US Timothy D. Cushing - Pacifica CA, US Xiaolin Hao - Foster City CA, US Xiao He - Foster City CA, US Andreas Reichelt - Moorpark CA, US Robert M. Rzasa - Ventura CA, US Jennifer Seganish - Scotch Plains NJ, US Youngsook Shin - Emeryville CA, US Dawei Zhang - Thousand Oaks CA, US
Assignee:
Amgen Inc. - Thousand Oaks CA
International Classification:
C07D 215/12
US Classification:
546176
Abstract:
Substituted bicyclic heteroaryls and compositions containing them, for the treatment of general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, including but not restricted to autoimmune diseases such as systemic lupus erythematosis (SLE), myestenia gravis, rheumatoid arthritis, acute disseminated encephalomyelitis, idiopathic thrombocytopenic purpura, multiples sclerosis, Sjoegren's syndrome and autoimmune hemolytic anemia, allergic conditions including all forms of hypersensitivity. The present invention also enables methods for treating cancers that are mediated, dependent on or associated with p110δ activity, including nut not restricted to leukemias, such as Acute Myeloid leukaemia (AML) Myelo-dysplastic syndrome (MDS) myelo-proliferative diseases (MPD) Chronic Myeloid Leukemia (CML) T-cell Acute Lymphoblastic leukaemia (T-ALL) B-cell Acute Lymphoblastic leukaemia (B-ALL) Non Hodgkins Lymphoma (NHL) B-cell lymphoma and solid tumors, such as breast cancer.
Method For Depositing Boron-Rich Films For Lithographic Mask Applications
Victor Nguyen - Novato CA, US Yi Chen - Sunnyvale CA, US Mihaela Balseanu - Sunnyvale CA, US Isabelita Roflox - Union City CA, US Li-Qun Xia - Cupertino CA, US Derek R Witty - Fremont CA, US
Assignee:
Applied Materials, Inc. - Santa Clara CA
International Classification:
C23C 16/38 C23C 16/30
US Classification:
4272495, 42725538, 427255394, 4272557
Abstract:
Methods for processing a substrate with a boron rich film are provided. A patterned layer of boron rich material is deposited on a substrate and can be used as an etch stop. By varying the chemical composition, the selectivity and etch rate of the boron rich material can be optimized for different etch chemistries. The boron rich materials can be deposited over a layer stack substrate in multiple layers and etched in a pattern. The exposed layer stack can then be etched with multiple etch chemistries. Each of the boron rich layers can have a different chemical composition that is optimized for the multiple etch chemistries.
Yi Chen - San Mateo CA, US Timothy D. Cushing - Pacifica CA, US Xiaolin Hao - Foster City CA, US Xiao He - Foster City CA, US Andreas Reichelt - Moorpark CA, US Robert M. Rzasa - Ventura CA, US Jennifer Seganish - Scotch Plains NJ, US Youngsook Shin - Emeryville CA, US Dawei Zhang - Thousand Oaks CA, US
Substituted bicyclic heteroaryls and compositions containing them, for the treatment of general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, including but not restricted to autoimmune diseases such as systemic lupus erythematosis (SLE), myestenia gravis, rheumatoid arthritis, acute disseminated encephalomyelitis, idiopathic thrombocytopenic purpura, multiples sclerosis, Sjoegren's syndrome and autoimmune hemolytic anemia, allergic conditions including all forms of hypersensitivity, The present invention also enables methods for treating cancers that are mediated, dependent on or associated with p110δ activity, including but not restricted to leukemias, such as Acute Myeloid leukaemia (AML) Myelo-dysplastic syndrome (MDS) myelo-proliferative diseases (MPD) Chronic Myeloid Leukemia (CML) T-cell Acute Lymphoblastic leukaemia (T-ALL) B-cell Acute Lymphoblastic leukaemia (B-ALL) Non Hodgkins Lymphoma (NHL) B-cell lymphoma and solid tumors, such as breast cancer.
Yi S Chen DO 13620 38 Ave STE 6A, Flushing, NY 11354 (718)9614636 (phone), (718)4615765 (fax)
Education:
Medical School University of New England College of Osteopathic Medicine Graduated: 1992
Procedures:
Breast Biopsy Breast Reconstruction Destruction of Lesions on the Anus Hemorrhoid Procedures Mastectomy Appendectomy Hernia Repair Laparoscopic Appendectomy Laparoscopic Gallbladder Removal Pilonidal Cyst Excision Proctosigmoidoscopy Small Bowel Resection Thyroid Gland Removal Varicose Vein Procedures
Conditions:
Breast Disorders Hemorrhoids Malignant Neoplasm of Female Breast Varicose Veins Abdominal Hernia
Languages:
Chinese English
Description:
Dr. Chen graduated from the University of New England College of Osteopathic Medicine in 1992. He works in Flushing, NY and specializes in General Surgery. Dr. Chen is affiliated with Flushing Hospital Medical Center and New York-Presbyterian Queens.
Dr. Chen graduated from the Zhejiang Univ Sch of Med, Zhejiang, China in 2006. She works in Choctaw, OK and specializes in Family Medicine. Dr. Chen is affiliated with St Anthony Hospital.
Northwestern Medical GroupNorthwestern Medical Faculty Foundation Pathology 251 E Huron St STE 7-218A, Chicago, IL 60611 (312)9263211 (phone), (312)9264559 (fax)
Northwestern Medical GroupNorthwestern Memorial Hospital Pathology 251 E Huron St STE 7-325, Chicago, IL 60611 (312)9260931 (phone), (312)9263127 (fax)
Education:
Medical School First Military Med Univ, Fac of Med, Guangzhou, Guangdong, China Graduated: 1984
Languages:
English
Description:
Dr. Chen graduated from the First Military Med Univ, Fac of Med, Guangzhou, Guangdong, China in 1984. She works in Chicago, IL and 1 other location and specializes in Anatomic Pathology & Clinical Pathology. Dr. Chen is affiliated with Alexian Brothers Medical Center and Northwestern Memorial Hospital.
Sutter Medical GroupAlhambra Family Practice & Residency Program 1201 Alhambra Blvd STE 300, Sacramento, CA 95816 (916)4514400 (phone), (916)7317956 (fax)
Languages:
English Spanish
Description:
Ms. Chen works in Sacramento, CA and specializes in Family Medicine. Ms. Chen is affiliated with Sutter Santa Rosa Regional Hospital.
Jan 2010 to 2000 Owner and DirectorDeloitte Tax LLP San Jose, CA Jul 2008 to Jan 2010 International Tax ConsultantLincoln Broadcasting Company KTSF Channel 26 Brisbane, CA Sep 2006 to Nov 2006 Accountant (Intern)Deloitte Touche Tohmatsu CPA Ltd
Jul 2001 to Jul 2005 Tax and Business Advisory Services ConsultantMotorola (China) Electronics Ltd. (Tianjin P.R. China)
Nov 2000 to May 2001 Cost Accountant (Intern)
Education:
San Jose State University San Jose, CA Sep 2006 to Jul 2008 MS in TaxationTianjin University of Finance and Economics Sep 1997 to Jun 2001 Bachelor of Economics in Finance and Taxation
Skills:
Proficient in various PC applications, such as Windows, PowerPoint and Microsoft word, Excel. Fluent in Chinese and English.
Excel Optometry San Diego, CA 2010 to 2011 Office AssistantNorth America Investment Interactive Ltd
2008 to 2009 Financial Editor AssistantChina Minsheng Bank
2005 to 2008 Executive AssistantChina Construction Bank
2003 to 2004 Bank Teller
Education:
California School of Real Estate Castro Valley, CA Jan 2011 to Jan 2012 California Real Estate Licensee in Real EstateBeijing University of Aeronautics and Astronautics 2003 Bachelor of Arts in International Economy and Trade
Yi Chen (1999-2003), Justin Haba (2000-2003), Marika Wasaznik (1998-1999), Nasser Jahani Asl (1999-2003), Daniel Wong (1993-1997), Kamaldeep Dhanoa (1997-2001)