Yong P Liu

US Patent:

20100138511, Jun 3, 2010

Filed:

Jun 28, 2007

Appl. No.:

12/452033

Inventors:

Yang Guo - Plainsboro NJ, US
Chao Liang - Brooklyn NY, US
Yong Liu - Brooklyn NY, US

International Classification:

G06F 15/16

US Classification:

709207

Abstract:

A method and apparatus are described for scheduling content delivery in a peer-to-peer network, including receiving a message from a peer, classifying the received message, storing the classified message in one of a plurality of queues based on the classification, generating responses to messages based on a priority of the queue in which the classified message is stored and transmitting content to all peers in the peer-to-peer network. Also described are a method and apparatus for scheduling content delivery in a peer-to-peer network, including receiving one of a message and content from one of a content source server and a peer, classifying the received message, storing the classified message in one of a plurality of queues based on the classification, storing the received content, generating responses to messages based on a priority of the queue in which the classified message is stored and transmitting content to all other peers in the peer-to-peer network.

US Patent:

20110047215, Feb 24, 2011

Filed:

Feb 27, 2008

Appl. No.:

12/919168

Inventors:

Yang Guo - West Windsor NJ, US
Chao Liang - Brooklyn NY, US
Yong Liu - Brooklyn NY, US

International Classification:

G06F 15/16

US Classification:

709204

Abstract:

A method and apparatus are described including forwarding data in a transmission queue to a first peer in a same cluster, computing an average transmission queue size to a threshold, sending a signal to a cluster head based on a result of the comparison. A method and apparatus are also described including forwarding data in a transmission queue to a peer associated with an upper level peer, forwarding data in a playback buffer to a peer in a lower level cluster responsive to a first signal in a signal queue associated with the lower level cluster, determining if the playback buffer has exceeded a threshold for a period of time, sending a second signal to a source server based on a result of the determination.

US Patent:

20120005304, Jan 5, 2012

Filed:

Mar 25, 2009

Appl. No.:

13/138610

Inventors:

Yang Guo - Princeton Junction NJ, US
Sha Hua - Brooklyn NY, US
Hang Liu - Yardley PA, US
Yong Liu - Brooklyn NY, US
Shivendra Panwar - Freehold NJ, US

Assignee:

THOMSON LICENSING - Princeton NJ

International Classification:

G06F 15/16

US Classification:

709217

Abstract:

A method and apparatus are described including receiving content from a base station, storing the received content, receiving a second message from a first member of a network, determining a highest expected layer, a lowest layer received by the first member of the network requesting help, a highest layer that needs to be multicast to the first member of the network, and a lowest layer that needs to be multicast to the first member of the network, retrieving the stored content responsive to the message and multicasting the retrieved content to the first member of the network responsive to the determining act.

US Patent:

20120110609, May 3, 2012

Filed:

Jun 30, 2009

Appl. No.:

13/381508

Inventors:

Yang Guo - Princeton Junction NJ, US
Hao Hu - Brooklyn NY, US
Yong Liu - Brooklyn NY, US

Assignee:

Thomson Licensing LLC - Princeton NJ

International Classification:

H04H 60/32
H04L 12/28

US Classification:

725 14

Abstract:

A method and apparatus are described including receiving buffer maps of neighbor peers, measuring serving rates from the neighbor peers, measuring serving rates to the neighbor peers, requesting a unit of data from one of the neighbor peers responsive to information in the buffer maps of the neighbor peers at a rate responsive to the serving rate from the one of the neighbor peers, receiving incoming requests for units of data, sorting the incoming requests into a plurality of queues, selecting one of the incoming requests to serve responsive to the serving rates to the neighbor peers corresponding to the incoming request, updating the queues and selecting a new neighbor peer.

US Patent:

57766800, Jul 7, 1998

Filed:

Jul 21, 1995

Appl. No.:

8/505509

Inventors:

Michael J. Leibowitz - Manalapan NJ
Yong Liu - Piscataway NJ

Assignee:

University of Medicine & Dentistry of New Jersey - Newark NJ

International Classification:

C12Q 168
C12P 1934
C07H 2104

US Classification:

435 6

Abstract:

The present invention pertains to a method for diagnosing for Pneumocystis carinii by detecting the presence of a nucleic acid sequence containing the 26S rRNA gene specific for Pneumocystis carinii. More particularly, this invention relates to a method for diagnosing for Pneumocystis carinii which comprises amplifying a sample of DNA from Pneumocystis carinii by polymerase chain reaction (PCR) using species specific primers and detecting the PCR products with species specific radioactive or non-radioactive oligonucleotide probes. This invention also relates to a method for diagnosing for various species of Pneumocystis carinii by detecting the presence of a nucleic acid sequence containing the particular 16S or 26S rRNA gene sequence specific for that species of Pneumocystis carinii.

US Patent:

58494847, Dec 15, 1998

Filed:

Jun 19, 1995

Appl. No.:

8/491690

Inventors:

Michael J. Leibowitz - Manalpan NJ
Yong Liu - Piscataway NJ

Assignee:

University of Medicine & Dentistry of NJ - Piscataway NJ

International Classification:

C12Q 168
C12P 1934
C07H 2104

US Classification:

435 6

Abstract:

The present invention pertains to an in vitro method for assaying for an inhibitor of the catalytic Group I self-splicing intron reaction in the nuclear rRNA genes of Pheumocystis carinii which comprises the steps of (a) providing a DNA template containing the intron (I) from the 26S rRNA gene in Pneumocystis carinii and a portion of the 5' and 3' flanking exons (E1 and E2, respectively) between nucleotides 1963 and 2267 of 26S rRNA (660 nucleotides of amplified rRNA gene including the group I intron); (b) preparing an RNA precursor by transcription of the DNA template in the presence of labeled nucleoside triphosphates to produce a labeled RNA precursor (E1-I-E2); (c) purifying the RNA precursor; (d) incubating the RNA precursor and the inhibitor in the presence of guanosine triphosphate and magnesium ions; and (e) determining the degree of inhibition by the inhibitor on the intron splicing reaction in the RNA precursor by measuring the amount of labeled splicing intermediates and splicing products.

US Patent:

20190219555, Jul 18, 2019

Filed:

Jan 11, 2019

Appl. No.:

16/245703

Inventors:

- West Lafayette IN, US
Roy Helmy - Kenilworth NJ, US
Yangjie Li - West Layfayette IN, US
Yong Liu - Kenilworth NJ, US

International Classification:

G01N 33/15
H01J 49/00
H01J 49/04

Abstract:

The invention generally relates to methods for analyzing stability of an active pharmaceutical agent. In certain aspects, the methods involve obtaining an active pharmaceutical agent, and distributing the active pharmaceutical agent into one or more microdroplets. The one or more microdroplets including the active pharmaceutical agent are then subjected to one or more conditions that force degradation of the active pharmaceutical agent in each of the one or more microdroplets. The one or more microdroplets are then analyzed to determine a ratio of the active pharmaceutical agent to that of a degradation product of the active pharmaceutical agent, thereby analyzing stability of an active pharmaceutical agent.

US Patent:

20170233383, Aug 17, 2017

Filed:

Sep 25, 2015

Appl. No.:

15/514584

Inventors:

Zachary E. DANCE - Rahway NJ, US
Scott TRZASKA - Raritan NJ, US
Yong LIU - Rahway NJ, US
Richard John VARSOLONA - Rahway NJ, US
Gregory YORK - Rahway NJ, US
- Rahway NJ, US

Assignee:

Merck Sharp & Dohme Corp. - Rahway NJ

International Classification:

C07D 417/12
C07C 309/30

Abstract:

The present invention provides four crystalline forms of verubecestat, as well as pharmaceutically acceptable compositions thereof, each of which may be useful in treating, preventing, ameliorating, and/or delaying the onset of an Aβ pathology and/or a symptom or symptoms thereof. Non-limiting examples of such Aβ pathologies, including Alzheimer's disease, are disclosed herein.