Yoon J Lee

US Patent:

8524697, Sep 3, 2013

Filed:

Dec 18, 2008

Appl. No.:

12/736063

Inventors:

John C. Anthes - Cranford NJ, US
Kevin D. McCormick - Basking Ridge NJ, US
John A. Hey - Edmond OK, US
Robert G. Aslanian - Rockaway NJ, US
Purakkattle J. Biju - Piscataway NJ, US
Michael Y. Berlin - Flemington NJ, US
Hongwu Yang - Westfield NJ, US
Yeon-Hee Lim - Woodbridge NJ, US
Yoon Joo Lee - Scotch Plains NJ, US
Rema Danielle Bitar - Clifton NJ, US
Phillippa H. Solomon - Edison NJ, US

Assignee:

Merck Sharp & Dohme Corp. - Rahway NJ

International Classification:

A01N 43/00
A61K 31/33
C07D 215/00
C07D 277/62

US Classification:

514183, 546157, 548160

Abstract:

The present invention provides compounds of Formula (I), and pharmaceutically acceptable salts, solvates, esters, prodrugs, tautomers, or isomers of said compounds), having the general structure:.

US Patent:

20110262368, Oct 27, 2011

Filed:

Dec 18, 2008

Appl. No.:

12/736064

Inventors:

John C. Anthes - Cranford NJ, US
Kevin D. McCormick - Basking Ridge NJ, US
John A. Hey - Edmond OK, US
Robert G. Aslanian - Rickaway NJ, US
Purakkattle J. Biju - Piscataway NJ, US
Michael Y. Berlin - Flemington NJ, US
Daniel M. Solomon - Edison NJ, US
Philippa H. Solomon - Edison NJ, US
Hongwu Yang - Westfield NJ, US
Yeon-Hee Lim - Woodbridge NJ, US
Yoon Joo Lee - Scotch Plains NJ, US
Rema Danielle Bitar - Clifton NJ, US

Assignee:

Schering Corporation - Kenilworth NJ

International Classification:

A61K 31/58
C07J 31/00
A61K 31/573
A61P 25/00
A61P 27/02
A61P 27/14
A61P 29/00
A61P 11/06
A61P 11/00
A61P 17/00
A61P 17/06
A61P 17/04
A61P 31/12
A61P 31/00
A61P 11/02
A61P 37/06
A61P 37/08
A61P 11/10
C07J 43/00

US Classification:

424 43, 540108, 540111, 540 63, 552581, 514176, 514174, 514179

Abstract:

The present invention provides compounds of Formula (VII) and 11-keto analogs thereof, and pharmaceutically acceptable salts, solvates, esters, prodrugs, tautomers, and isomers of said compounds and said 11-keto analogs, having the general structure formula (VII): wherein L, R, R, R, R, and Rare selected independently of each other and as defined herein. Also provided are pharmaceutical compositions, methods of preparing, and methods of using such compounds in the treatment and prophylaxis of a wide range of immune, autoimmune, and inflammatory diseases and conditions. The novel compounds of the present invention possess useful pharmacological activity while having unexpectedly low systemic activity. Thus, the compounds of the invention represent a safer alternative to those known glucocorticoids which have poor side-effect profiles.

US Patent:

20120171126, Jul 5, 2012

Filed:

Jun 15, 2010

Appl. No.:

13/378893

Inventors:

Michael Y. Berlin - Kenilworth NJ, US
Yeon-Hee Lim - Kenilworth NJ, US
Rema D. Bitar - Kenilworth NJ, US
Kevin D. McCormick - Kenilworth NJ, US
Robert G. Aslanian - Kenilworth NJ, US
Yoon Joo Lee - Kenilworth NJ, US
Junying Zheng - Kenilworth NJ, US
Ying Huang - Kenilworth NJ, US
Walter Won - Kenilworth NJ, US

International Classification:

A61K 31/58
A61K 9/12
A61P 37/00
A61P 29/00
A61P 17/00
A61P 17/06
A61P 17/04
A61P 11/06
A61P 11/02
A61P 11/08
A61P 11/00
A61P 1/00
A61P 1/04
A61P 25/00
A61P 27/02
C07J 71/00

US Classification:

424 45, 540 53, 514176, 514171

Abstract:

The present invention provides compounds of Formula (I), and pharmaceutically acceptable salts, solvates, esters, prodrugs, tautomers, or isomers of said compounds), having the general structure: Formula (I) wherein L, R, R, R, R, R, and Rare selected independently of each other and as defined herein. The present invention also provides compounds (and salts, solvates, esters, prodrugs, tautomers, and isomers) of Formulas (H-A), (II-A1), (II-A2), (II-A2.1), (ll-A-2.2), (ll-A-2.3), (II-A4), (H-B), (H-C), (III), (IV), (V), (VI), as described herein. Also provided are pharmaceutical compositions, methods of preparing, and methods of using such compounds in the treatment and prophylaxis of a wide range of immune, autoimmune, and inflammatory diseases and conditions.

US Patent:

20140264400, Sep 18, 2014

Filed:

Jun 6, 2014

Appl. No.:

14/298875

Inventors:

- Ithaca NY, US
Yoon Ho Lee - Ithaca NY, US

Assignee:

Cornell University - Ithaca NY

International Classification:

H01L 25/16
H01L 33/58
H01L 25/00
H01L 31/0232

US Classification:

257 88, 257432, 438 23, 438 59

Abstract:

Techniques, systems, and devices are disclosed to provide multilayer platforms for integrating semiconductor integrated circuit dies, optical waveguides and photonic devices to provide intra-die or inter-die optical connectivity. For example, an integrated semiconductor device having integrated circuits respectively formed on different semiconductor integrated circuit dies is provided to include a carrier substrate structured to form openings on a top side of the carrier substrate; semiconductor integrated circuit dies fixed to bottom surfaces of the openings of the carrier substrate, each semiconductor integrated circuit die including a semiconductor substrate and an integrated circuit formed on the semiconductor substrate to include one or more circuit components, and each semiconductor integrated circuit die being structured to have a top surface substantially coplanar with the top side of the carrier substrate; and planar layers formed on top of the top surfaces of the semiconductor integrated circuit dies and the top side of the carrier substrate to include optical waveguides and photonic devices to provide (1) intra-die optical connectivity for photonic devices associated with a semiconductor integrated circuit die, or (2) inter-die optical connectivity for photonic devices associated with different semiconductor integrated circuit dies.

Address:

24202 Oakpor Dr, Douglaston, NY 11362

Phone:

(718)8237062

VIN:

2HNYD2H29AH528670

Make:

ACURA

Model:

MDX

Year:

2010