Yu Sun Li

US Patent:

20120214155, Aug 23, 2012

Filed:

Nov 2, 2010

Appl. No.:

13/505719

Inventors:

Yu Li - Duluth GA, US
Inger K. Damon - Decatur GA, US
Hui Zhao - Lilburn GA, US

International Classification:

C12Q 1/70
C07H 21/04

US Classification:

435 5, 536 2432

Abstract:

This disclosure relates to compositions and methods of their use in detection and identification of a chordopoxvirus in a sample, such as diagnosis of an infection in a subject. The compositions and methods allow for detection and identification of all non-avian low-GC content chordopoxviruses, identification of most known high-GC content chordopoxvirus, and species-specific detection of Canarypox virus, Fowlpox virus, and Sealpox virus.

US Patent:

20130072360, Mar 21, 2013

Filed:

Oct 8, 2012

Appl. No.:

13/647360

Inventors:

Yu Li - Johns Creek GA, US

International Classification:

A63B 21/00

US Classification:

482128, 482133

Abstract:

A chair-like exercising apparatus comprises a back, a seat, front legs, rear legs, and resistance element(s) which provide a broad range of resistance force adjustable by the user for the back extension exercise. The chair back pivotally connects to the rear legs directly, and pivotally connects to the front legs or rear legs through the resistance element(s). The resistance element comprises a compress-coil-spring cylinders (or constant-force-spring devices) and the cylinder holders (or the device holders). The resistance level of the back extension exercise is adjusted by switching the interchangeable compress-coil-spring cylinders (or constant-force-spring devices) of appropriate loads inside the cylinder holders (or device holders). A user sits on the chair and sway backward to perform back extension exercise after selecting an appropriate resistance level based on his/her physical condition. The apparatus is simple, affordable and can be used as a regular chair in its locked position. A regular back extension exercise with proper resistance force strengthens the low back muscles (erector spinae), improves and prevents the low back pain symptoms.

US Patent:

20220331385, Oct 20, 2022

Filed:

Apr 21, 2022

Appl. No.:

17/660051

Inventors:

Minjie HU - Foster City CA, US
Yu Li - Johns Creek GA, US
Xiaoling Liu - Pearland TX, US
Rebecca Hu - Foster City CA, US

Assignee:

Suzhou Prajna Biotech Co., Ltd. - Sip

International Classification:

A61K 35/768
A61K 39/39
A61K 35/745
A61P 35/00
A61K 35/741
A61K 45/06
C12N 7/00

Abstract:

Therapeutic methods for administering gut microbiota and oncolytic viruses to a subject are provided. The gut microbiota serve to pre-condition, the subject's immune system to antitumor responses and augments anticancer activity of the oncolytic vims. Combinations of the gut, microbiota and viruses and uses thereof for treating and preventing cancer are provided. The present disclosure also provides methods for building elite responder selection platforms through hierarchical clustering analysis of genomic profiles for human gut microbiome.

US Patent:

20190284646, Sep 19, 2019

Filed:

May 8, 2017

Appl. No.:

16/303006

Inventors:

- Bethesda MD, US
Yu Li - Johns Creek GA, US

Assignee:

The U.S.A., as represented by the Secretary, Department of Health and Human Services - Bethesda MD

International Classification:

C12Q 1/70
C12Q 1/6876

Abstract:

A real-time reverse transcriptase-polymerase chain reaction (RT-PCR) assay that utilizes multiplex primers and probes with degenerate nucleotides to detect divergent species of lyssavirus is described. The probes used in the RT-PCR assay target a highly conserved region at the 5′ end of the lyssavirus genome and are modified with either a minor groove binder (MGB) or locked nucleic acid (LNA) nucleotides to increase their melting temperature. The described assay detects all known lyssavirus species with a sensitivity and specificity superior to traditional hemi-nested PCR and the direct fluorescent antibody (DFA) test.

US Patent:

20190000899, Jan 3, 2019

Filed:

Mar 28, 2017

Appl. No.:

15/744295

Inventors:

Minjie HU - Foster City CA, US
Yu LI - Johns Creek GA, US
Xiaoling LIU - Pearland TX, US
Rebecca HU - Foster City CA, US

International Classification:

A61K 35/768
A61P 35/00
A61K 39/39
A61K 35/745

Abstract:

Therapeutic methods for administering gut microbiota and oncolytic viruses to a subject are provided. The gut microbiota serve to pre-condition, the subject's immune system to antitumor responses and augments anticancer activity of the oncolytic vims. Combinations of the gut. microbiota and viruses and uses thereof for treating and preventing cancer are provided. The present disclosure also provides methods for building elite responder selection platforms through hierarchical clustering analysis of genomic profiles for human gut microbiome.

US Patent:

20150352275, Dec 10, 2015

Filed:

Jan 14, 2013

Appl. No.:

14/760480

Inventors:

Yu LI - Johns Creek GA, US

International Classification:

A61M 3/02

Abstract:

A portable contact-washing device allows a user to wear a single-use finger cover for contact washing of rectal area using water that is delivered to the finger pad area through micro tubing by a mini water pump. This contact wash uses a limited amount of water for a sufficient hygienic wash to the rectal area after a bowel movement without causing irritation which is often associated of using toilet paper. The contact washing process is efficient and requires a small volume of water, and the contact-washing device is highly portable and easy to use outside of home. The finger cover may be made of biodegradable material and will be discarded after the use.