Yubin I Qiu

US Patent:

20130197016, Aug 1, 2013

Filed:

Oct 25, 2011

Appl. No.:

13/878678

Inventors:

Mitchell Brigell - Belmont MA, US
Peter End - Oberwil, CH
Vinayak Hosagrahara - Chembur, IN
Bruce D. Jaffee - Hopkinton MA, US
Erik Meredith - Hudson MA, US
Ronald Keith Newton - Hanover MA, US
Stephen Poor - Winthrop MA, US
Yubin Qiu - Newton MA, US

International Classification:

A61K 31/506
A61K 31/44
A61K 31/505
A61K 31/519
A61K 31/4709

US Classification:

5142641, 514275, 514269, 514312, 5142651, 514350

Abstract:

The use of vascular endothelial growth factor receptor 2 inhibitors or a pharmaceutically acceptable salt thereof for the treatment of ocular vascular disease is provided. Dosing regimes, including once weekly administration, of certain VEGF-R2 inhibitors are provided which deliver therapeutically effective concentrations of the VEGF-R2 compounds in ocular tissues for at least one week for the treatment of ocular vascular disease.

US Patent:

20220356236, Nov 10, 2022

Filed:

Jun 30, 2022

Appl. No.:

17/809941

Inventors:

- Basel, CH
Ana Maria CARRION - Wellesley MA, US
James Edgar CHASTAIN - Acton MA, US
Kirk Lee CLARK - Stow MA, US
Joy Gispati GHOSH - Boston MA, US
Shawn Michael HANKS - Sudbury MA, US
Nicole HAUBST - Munchen, DE
Ganesh Rajan IYER - South Grafton MA, US
Nina MOKER - Koln, DE
Andrew Anh NGUYEN - Brookline MA, US
Stephen Hendrick POOR - Winthrop MA, US
Yubin QIU - Newton MA, US
Nalini Velamur RANGASWAMY - Wakefield MA, US
Michael STEFANIDAKIS - Brookline MA, US
Engin TOKSOZ - Munchen, DE
Michael Zbigniew TWAROG - Cambridge MA, US

International Classification:

C07K 16/22
A61P 27/02
C07K 16/46

Abstract:

The present disclosure provides anti-BTC antibodies, methods of producing said antibodies, pharmaceutical compositions comprising said antibodies, and methods of using said antibodies. The present disclosure also provides multi-specific binding molecules, e.g., bispecific antibodies, comprising a BTC binding moiety and an anti-VEGF binding moiety.

US Patent:

20220348646, Nov 3, 2022

Filed:

Jun 30, 2022

Appl. No.:

17/809943

Inventors:

- Basel, CH
Ana Maria CARRION - Wellesley MA, US
James Edgar CHASTAIN - Acton MA, US
Kirk Lee CLARK - Stow MA, US
Joy Gispati GHOSH - Boston MA, US
Shawn Michael HANKS - Sudbury MA, US
Nicole HAUBST - , US
Ganesh Rajan IYER - South Grafton MA, US
Nina MOKER - , US
Andrew Anh NGUYEN - Brookline MA, US
Stephen Hendrick POOR - Winthrop MA, US
Yubin QIU - Newton MA, US
Nalini Velamur RANGASWAMY - Wakefield MA, US
Michael STEFANIDAKIS - Brookline MA, US
Engin TOKSOZ - , US
Michael Zbigniew TWAROG - Cambridge MA, US

International Classification:

C07K 16/22
A61P 27/02
C07K 16/46

Abstract:

The present disclosure provides anti-BTC antibodies, methods of producing said antibodies, pharmaceutical compositions comprising said antibodies, and methods of using said antibodies. The present disclosure also provides multi-specific binding molecules, e.g., bispecific antibodies, comprising a BTC binding moiety and an anti-VEGF binding moiety.