James F. Callahan - King of Prussia PA, US Yue H. Li - King of Prussia PA, US
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
A61K 31/38 C07D 327/04
US Classification:
514443, 549 31
Abstract:
The present invention provides novel compounds and methods for using them to treat diseases with aminothiophene inhibitors of IKK-β phosphorylation of IκB. In yso doing these aminothiophene inhibitors block pathological activation of transcription factor NF-κB in which diseases excessive activation of NF-κB is implicated.
The present invention provides novel compounds and methods for using them to treat diseases with aminothiophene inhibitors of IKK-β phosphorylation of IκB. In so doing these aminothiophene inhibitors block pathological activation of transcription factor NF-κB in which diseases excessive activation of NF-κB is implicated.
Karen Evans - Collegeville PA, US Frank Coppo - Collegeville PA, US Kate Dwornik - Durham NC, US Jennifer Gale - Durham NC, US Dulce Garrido - Durham NC, US Yue Li - Collegeville PA, US Mehul Patel - Collegeville PA, US Francis Tavares - Durham NC, US Stephen Thomson - Durham NC, US Scott Dickerson - Durham NC, US Andrew Peat - Durham NC, US Steven Sparks - Durham NC, US Pierette Banker - Durham NC, US Joel Cooper - Durham NC, US
The invention relates to glycogen phosphorylase inhibitor compounds, pharmaceutical compositions of these compounds, methods of treatment using the pharmaceutical compositions to treat diabetes, conditions associated with diabetes, and/or tissue ischemia, including myocardial ischemia, and processes for making the compounds.
- Brentford, GB Michael G DARCY - King of Prussia PA, US Jason W. DODSON - King of Prussia PA, US Xiaoyang DONG - Collegeville PA, US Terry V. HUGHES - Blue Bell PA, US Jianxing KANG - Collegeville PA, US Lara LEISTER - Collegeville PA, US Yiqian LIAN - Collegeville PA, US Yue LI - King of Prussia PA, US John F. MEHLMANN - Collegeville PA, US Neysa NEVINS - Collegeville PA, US Joshi M. RAMANJULU - Collegeville PA, US Joseph J. ROMANO - Collegeville PA, US Gren Z. WANG - Collegeville PA, US Guosen YE - Collegeville PA, US Daohua ZHANG - Collegeville PA, US
Assignee:
GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED - Brentford
- Redmond WA, US Xin HE - Bellevue WA, US Milica JOVANOVIC - Prague, CZ Artur Pawel KANIA - Bellevue WA, US Namendra KUMAR - Redmond WA, US Rui LIANG - Sammamish WA, US Yue LI - Bellevue WA, US Joel Harodi MARQUEZ CATANO - Seattle WA, US Abhilash Chandrasekharan NAIR - Bothell WA, US Gaurav PANCHOLI - Redmond WA, US Jindrich PARUS - Prague, CZ Martin PETRLA - Prague, CZ Denis POSTU - Prague, CZ Rama Krishan Prasad SATYA PRAKASH - Redmond WA, US Kensaku SUEDA - Kirkland WA, US Balvinder Kaur THIND - Sammamish WA, US Hao XU - Issaquah WA, US
Assignee:
MICROSOFT TECHNOLOGY LICENSING, LLC - Redmond WA
International Classification:
H04L 29/06 H04L 12/18 G06Q 10/10
Abstract:
An online meeting system begins the process of connecting a user to an online meeting when the user enters a prejoin dialog for choosing meeting settings, rather than waiting until the user chooses to actually join the meeting after entering settings. Starting the meeting connection process at this time allows a shorter perceived connection time to the meeting and thus reduces user frustration with the meeting system.
Computational Alignment Of Aggregated Data To Generate Actionable Output
- Redmond WA, US YUE LI - Redmond WA, US ERIC WEBER - Sunnyvale CA, US ZHAOYING HAN - San Jose CA, US XIAOYAN CHENG - San Jose CA, US
Assignee:
Microsoft Technology Licensing, LLC - Redmond WA
International Classification:
G06Q 50/20 G06Q 10/06 G06F 17/30
Abstract:
Technologies for computationally aligning aggregated data include obtaining a set of member records from an online system and obtaining a set of job records from a management system. An aggregate alignment score is calculated by comparing member skills data extracted from the set of member records to job skills data extracted from the set of job records. The aggregate alignment score is a measure of a mismatch between the member skills data for the set of member records and the job skills data for the set of job records. Based on the aggregate alignment score, a skill is identified that is actionable to address the mismatch between the member skills data and the job skills data. Actionable output is generated that replaces, modifies, or supplements previously-generated course recommendation data that does not map to the identified skill with new course recommendation data that maps to the identified skill.
Youtube
Yueli @li ~ part 2
Duration:
10m 38s
Yueli @li ~ 40 songs [[ covers version ]] #ti...
Duration:
15m 48s
San Yue Li De Xiao Yu ( ) - Karaoke
Duration:
4m 28s
san yue li de xiao yu dj remix
san yue li de xiao yu ... dj remix karaoke salah satu lagu kami mempe...
Duration:
4m 31s
Yue Li: Patient Satisfaction, Public Reportin...
A public health seminar recorded on October 31, 2016 featuring Yue Li,...