Yue Li

US Patent:

7183311, Feb 27, 2007

Filed:

Apr 11, 2003

Appl. No.:

10/510841

Inventors:

James F. Callahan - King of Prussia PA, US
Yue H. Li - King of Prussia PA, US

Assignee:

SmithKline Beecham Corporation - Philadelphia PA

International Classification:

A61K 31/38
C07D 327/04

US Classification:

514443, 549 31

Abstract:

The present invention provides novel compounds and methods for using them to treat diseases with aminothiophene inhibitors of IKK-β phosphorylation of IκB. In yso doing these aminothiophene inhibitors block pathological activation of transcription factor NF-κB in which diseases excessive activation of NF-κB is implicated.

US Patent:

7375131, May 20, 2008

Filed:

May 29, 2003

Appl. No.:

10/516836

Inventors:

James F. Callahan - King of Prussia PA, US
Yue Hu Li - King of Prussia PA, US

Assignee:

SmithKlineBeecham Corp. - Philadelphia PA

International Classification:

A61K 31/38
C07D 333/36

US Classification:

514445, 514447, 514448, 549 63, 549 64, 549 69, 549 72

Abstract:

The present invention provides novel compounds and methods for using them to treat diseases with aminothiophene inhibitors of IKK-β phosphorylation of IκB. In so doing these aminothiophene inhibitors block pathological activation of transcription factor NF-κB in which diseases excessive activation of NF-κB is implicated.

US Patent:

20060116419, Jun 1, 2006

Filed:

Dec 5, 2003

Appl. No.:

10/537697

Inventors:

James Callahan - King of Prussia PA, US
Yue Li - Collegeville PA, US

International Classification:

A61K 31/381
C07D 333/42

US Classification:

514447000, 549063000

Abstract:

The present invention provides a specific compound and methods for treating diseases related to the inhibition of IKK-β phosphorylation of IK.

US Patent:

20070249670, Oct 25, 2007

Filed:

Nov 4, 2005

Appl. No.:

11/718804

Inventors:

Karen Evans - Collegeville PA, US
Frank Coppo - Collegeville PA, US
Kate Dwornik - Durham NC, US
Jennifer Gale - Durham NC, US
Dulce Garrido - Durham NC, US
Yue Li - Collegeville PA, US
Mehul Patel - Collegeville PA, US
Francis Tavares - Durham NC, US
Stephen Thomson - Durham NC, US
Scott Dickerson - Durham NC, US
Andrew Peat - Durham NC, US
Steven Sparks - Durham NC, US
Pierette Banker - Durham NC, US
Joel Cooper - Durham NC, US

Assignee:

SMITHKLINE BEECHAM CORPORATION - Philadelphia PA

International Classification:

A61K 31/24
A61K 31/381
A61K 31/40
A61K 31/4164
A61K 31/445
A61K 31/47
C07C 229/72
C07D 207/16
C07D 211/18
C07D 215/38
C07D 233/64
C07D 333/50

US Classification:

514313000, 514319000, 514400000, 514423000, 514438000, 514443000, 514539000, 546162000, 546205000, 548334100, 548533000, 549057000, 560034000

Abstract:

The invention relates to glycogen phosphorylase inhibitor compounds, pharmaceutical compositions of these compounds, methods of treatment using the pharmaceutical compositions to treat diabetes, conditions associated with diabetes, and/or tissue ischemia, including myocardial ischemia, and processes for making the compounds.

US Patent:

20220335661, Oct 20, 2022

Filed:

Feb 28, 2020

Appl. No.:

17/753425

Inventors:

- Mountain View CA, US
Anish Dhesikan - Brooklyn NY, US
Kai Yu - San Francisco CA, US
Jacob Hanshaw - San Francisco CA, US
Yue Li - Santa Clara CA, US
Charles DiFazio - Mountain View CA, US

International Classification:

G06T 11/00
G06V 20/20

Abstract:

Systems and methods for accessing augmented reality (AR) content, including dynamic AR content, relatively quickly, and relatively easily, are provided. An enabled target entity may be identified within a camera view of a mobile computing device, and a server computing device may identify the target entity, match the target entity with dynamic AR content, and transmit the dynamic AR content to the client computing device. This may allow users to consume content-rich information and/or to experience real time interaction with the images and objects in their surroundings, that would otherwise be difficult and/or unrealistic to condense into physical media, and/or that would be otherwise difficult and/or unrealistic to provide in a real time, interactive experience.

US Patent:

20230071675, Mar 9, 2023

Filed:

May 17, 2022

Appl. No.:

17/663749

Inventors:

- Brentford, GB
Michael G DARCY - King of Prussia PA, US
Jason W. DODSON - King of Prussia PA, US
Xiaoyang DONG - Collegeville PA, US
Terry V. HUGHES - Blue Bell PA, US
Jianxing KANG - Collegeville PA, US
Lara LEISTER - Collegeville PA, US
Yiqian LIAN - Collegeville PA, US
Yue LI - King of Prussia PA, US
John F. MEHLMANN - Collegeville PA, US
Neysa NEVINS - Collegeville PA, US
Joshi M. RAMANJULU - Collegeville PA, US
Joseph J. ROMANO - Collegeville PA, US
Gren Z. WANG - Collegeville PA, US
Guosen YE - Collegeville PA, US
Daohua ZHANG - Collegeville PA, US

Assignee:

GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED - Brentford

International Classification:

C07D 403/14
C07D 405/14
C07D 413/14
C07D 487/22
C07D 493/10
C07D 498/18
C07F 9/6558

Abstract:

Disclosed are compounds having the formula: