Yuping Te Tan

US Patent:

6468748, Oct 22, 2002

Filed:

Feb 29, 2000

Appl. No.:

09/515277

Inventors:

Joseph A. Monforte - Berkeley CA
Thomas A. Shaler - Fremont CA
Yuping Tan - Fremont CA
Christopher H. Becker - Palo Alto CA

Assignee:

Sequenom, Inc. - San Diego CA

International Classification:

C12Q 168

US Classification:

435 6, 435 911, 435 912, 536 221, 536 231, 536 2433, 250281, 250282, 250283, 250280, 250287, 210635, 210656

Abstract:

This invention relates to methods for screening nucleic acids for mutations by analyzing nonrandomly fragmented nucleic acids using mass spectrometric techniques and to procedures for improving mass resolution and mass accuracy of these methods of detecting mutations.

US Patent:

6566055, May 20, 2003

Filed:

Jun 3, 1998

Appl. No.:

09/089730

Inventors:

Joseph A. Monforte - Berkeley CA
Thomas A. Shaler - Fremont CA
Yuping Tan - Fremont CA
Christopher H. Becker - Menlo Part CA

Assignee:

Sequenom, Inc. - San Diego CA

International Classification:

C12Q 168

US Classification:

435 6, 435 911, 435 912, 250281

Abstract:

This invention relates to methods for screening nucleic acids for polymorphisms by analyzing amplified target nucleic acids using mass spectrometric techniques and to procedures for improving mass resolution and mass accuracy of these methods of detecting polymorphisms.

US Patent:

6537756, Mar 25, 2003

Filed:

Jul 6, 2000

Appl. No.:

09/611216

Inventors:

Mark J. Rupar - Wilmington DE
William P. Donovan - Levittown PA
Yuping Tan - Fremont CA
Annette C. Slaney - Hamilton Square NJ

Assignee:

Monsanto Technology, LLC - St. Louis MO

International Classification:

C12N 1532

US Classification:

435 6, 536 231, 536 2371, 4353201, 4352523, 43525233, 43525231, 43525234, 435325, 435419, 435 691, 436 63

Abstract:

Disclosed is a novel -endotoxin, designated CryET29, that exhibits insecticidal activity against siphonapteran insects, including larvae of the cat flea ( ), as well as against coleopteran insects, including the southern corn rootworm ( ), western corn rootworm ( ), Colorado potato beetle ( ), Japanese beetle ( ), and red flour beetle ( ). Also disclosed are nucleic acid segments encoding CryET29, recombinant vectors, host cells, and transgenic plants comprising a cryET29 DNA segment. Methods for making and using the disclosed protein and nucleic acid segments are disclosed as well as assays and diagnostic kits for detecting cryET29 and CryET29 sequences in vivo and in vitro.

US Patent:

6555655, Apr 29, 2003

Filed:

May 3, 2000

Appl. No.:

09/563269

Inventors:

Mark J. Rupar - Wilmington DE
William P. Donovan - Levittown PA
Elizabeth Pease - Danville PA
Yuping Tan - Fremont CA
Annette C. Slaney - Burlington NJ
Thomas M. Malvar - Troy MO
James A. Baum - Webster Groves MO

Assignee:

Monsanto Technology, LLC - St. Louis MO

International Classification:

C07K 14325

US Classification:

530350, 514 2, 514 12, 536 2371

Abstract:

Disclosed are novel insecticidal polypeptides, and compositions comprising these polypeptides, peptide fragments thereof, and antibodies specific therefor. Also disclosed are vectors, transformed host cells, and transgenic plants that contain nucleic acid segments that encode the disclosed -endotoxin polypeptides. Also disclosed are methods of identifying related polypeptides and polynucleotides, methods of making and using transgenic cells comprising these polynucleotide sequences, as well as methods for controlling an insect population, such as Colorado potato beetle, southern corn rootworm and western corn rootworm, and for conferring to a plant resistance to a target insect species.

US Patent:

6618679, Sep 9, 2003

Filed:

Jan 27, 2001

Appl. No.:

09/771372

Inventors:

Christine Loehrlein - Alameda CA
Dan Pollart - Alameda CA
Thomas Shaler - Fremont CA
Kathy Stephens - Fremont CA
Yuping Tan - Fremont CA
Linda Wong - Daly City CA
Joseph Monforte - Berkeley CA

Assignee:

Althea Technologies, Inc. - San Diego CA

International Classification:

G06F 1900

US Classification:

702 20, 435 6, 435 912, 536 2433

Abstract:

This invention provides methods, compositions and kits for gene expression analysis and gene expression profiling. The methods of the invention are highly sensitive; have a wide dynamic range; are rapid and inexpensive; have a high throughput; and allow the simultaneous differential analysis of a defined set of genes. The methods, compositions and kits of the invention also provide tools for gene expression data collection and relational data analysis.

US Patent:

6686452, Feb 3, 2004

Filed:

Mar 12, 2003

Appl. No.:

10/386972

Inventors:

Mark J. Rupar - Wilmington DE
William P. Donovan - Levittown PA
Yuping Tan - Fremont CA
Annette C. Slaney - Hamilton Square NJ

Assignee:

Monsanto Technology LLC - St. Louis MO

International Classification:

C07K 1612

US Classification:

5303879, 5303891, 5303895, 436 86, 435 71, 435 732

Abstract:

Disclosed is a novel -endotoxin, designated CryET29, that exhibits insecticidal activity against siphonapteran insects, including larvae of the cat flea ( ), as well as against coleopteran insects, including the southern corn rootworm ( ), western corn rootworm ( ), Colorado potato beetle ( ), Japanese beetle ( ), and red flour beetle ( ). Also disclosed are nucleic acid segments encoding CryET29, recombinant vectors, host cells, and transgenic plants comprising a cryET29 DNA segment. Methods for making and using the disclosed protein and nucleic acid segments are disclosed as well as assays and diagnostic kits for detecting cryET29 and CryET29 sequences in vivo and in vitro.

US Patent:

7078592, Jul 18, 2006

Filed:

Apr 7, 2003

Appl. No.:

10/408692

Inventors:

Mark J. Rupar - Wilmington DE, US
William P. Donovan - Levittown PA, US
Elizabeth Pease - Danville PA, US
Yuping Tan - Fremont CA, US
Annette C. Slaney - Burlington NJ, US
Thomas M. Malvar - Troy MO, US
James A. Baum - Webster Groves MO, US

Assignee:

Monsanto Technology LLC - St. Louis MO

International Classification:

A01H 5/00
A01H 5/10
C12N 15/82
C12N 15/32

US Classification:

800302, 800279, 536 2371, 435418

Abstract:

Disclosed are nucleic acids encoding novel insecticidal δ-endotoxin polypeptides, and vectors, transformed host cells, and transgenic plants that contain the nucleic acids. Also disclosed are methods of making and using transgenic cells comprising these polynucleotide sequences, as well as methods for controlling an insect population, such as Colorado potato beetle, southern corn rootworm and western corn rootworm, and for conferring to a plant resistance to a target insect species.

US Patent:

7186893, Mar 6, 2007

Filed:

Jan 29, 2004

Appl. No.:

10/767605

Inventors:

Mark J. Rupar - Wilmington DE, US
William P. Donovan - Levittown PA, US
Yuping Tan - Fremont CA, US
Annette C. Slaney - Hamilton Square NJ, US

Assignee:

Monsanto Technology LLC - St. Louis MO

International Classification:

A01H 5/00
A01H 5/10
C12N 5/04

US Classification:

800302, 435418

Abstract:

Disclosed are transgenic plants, seeds, and progeny from such plants comprising a cryET29 DNA segment. The cryET29 DNA segment encodes CryET29 crystal protein which comprises SEQ ID NO:2 and exhibits insecticidal activity against siphonapteran insects, including larvae of the cat flea (), as well as against coleopteran insects, including the southern corn rootworm (), western corn rootworm (), Colorado potato beetle (), Japanese beetle (), and red flour beetle ().