Zhen Ju Lin

US Patent:

6455571, Sep 24, 2002

Filed:

Oct 19, 1999

Appl. No.:

09/421787

Inventors:

Clarence J. Maring - Palatine IL
Yu Gui Gu - Grayslake IL
Hui-Ju Chen - Grayslake IL
Yuanwei Chen - North Haven CT
David A. Degoey - Kenosha WI
William J. Flosi - Des Plaines IL
Vincent L. Giranda - Gurnee IL
David J. Grampovnik - Waukegan IL
Warren M. Kati - Gurnee IL
Dale J. Kempf - Libertyville IL
April Kennedy - Grayslake IL
Larry L. Klein - Lake Forest IL
Allan C. Krueger - Gurnee IL
Zhen Lin - Gurnee IL
Darold L. Madigan - Elk Grove Village IL
Keith F. McDaniel - Grayslake IL
Steven W. Muchmore - Libertyville IL
Hing L. Sham - Mundelein IL
Kent D. Stewart - Gurnee IL
Vincent S. Stoll - Libertyville IL
Minghua Sun - Libertyville IL
Noah P. Tu - Gurnee IL
Frank L. Wagenaar - Gurnee IL
Gary T. Wang - Niles IL
Sheldon Wang - Grayslake IL
Paul E. Wiedeman - Deerfield IL
Yibo Xu - Ridgefield CT
Ming C. Yeung - Grayslake IL
Chen Zhao - Libertyville IL
Stephen Hanessian - Beaconsfield, CA
Malken Bayrakdarian - Verdun, CA
Xuehong Luo - Montreal, CA

Assignee:

Abbott Laboratories - Abbott Park IL

International Classification:

A61K 3140

US Classification:

514423, 514422, 514397, 514365, 514374, 548532, 548533, 548518, 5483147, 548205, 548236, 548237

Abstract:

Disclosed are compounds of the formula: which are useful for inhibiting neuraminidases from disease-causing microorganisms, especially, influenza neuraminidase. Also disclosed are compositions and methods for preventing and treating diseases caused by microorganisms having a neuraminidase, processes for preparing the compounds and synthetic intermediates used in these processes.

US Patent:

6518305, Feb 11, 2003

Filed:

Oct 19, 1999

Appl. No.:

09/422093

Inventors:

Clarence J. Maring - Palatine IL
Yuanwei Chen - North Haven CT
David A. Degoey - Kenosha WI
Vincent L. Giranda - Gurnee IL
David J. Grampovnik - Waukegan IL
Yu Gui Gu - Grayslake IL
Warren M. Kati - Gurnee IL
Dale J. Kempf - Libertyville IL
April Kennedy - Grayslake CO
Allan C. Krueger - Gurnee IL
Zhen Lin - Gurnee IL
Darold L. Madigan - Elk Grove Village IL
Steven W. Muchmore - Libertyville IL
Hing L. Sham - Mundelein IL
Kent D. Stewart - Gurnee IL
Vincent S. Stoll - Libertyville IL
Minghua Sun - Libertyville IL
Gary T. Wang - Niles IL
Sheldon Wang - Grayslake IL
Ming C. Yeung - Grayslake IL
Chen Zhao - Libertyville IL

Assignee:

Abbott Laboratories - Abbott Park IL

International Classification:

A61K 31195

US Classification:

514530, 514573, 548236, 548315, 5483451, 560122, 562504

Abstract:

Disclosed are compounds of the formula: which are useful for inhibiting neuraminidases from disease-causing microorganisms, especially, influenza neuraminidase. Also disclosed are compositions and methods for preventing and treating diseases caused by microorganisms having a neuraminidase, processes for preparing the compounds and synthetic intermediates used in these processes.

US Patent:

6831096, Dec 14, 2004

Filed:

Sep 24, 2002

Appl. No.:

10/253152

Inventors:

Clarence J. Maring - Palatine IL
Yu Gui Gu - Grayslake IL
Hui-Ju Chen - Grayslake IL
Yuanwei Chen - North Haven CT
David A. Degoey - Kenosha WI
William J. Flosi - Des Plaines IL
Vincent L. Giranda - Gurnee IL
David J. Grampovnik - Waukegan IL
Warren M. Kati - Gurnee IL
Dale J. Kempf - Libertyville IL
April Kennedy - Boulder CO
Larry L. Klein - Lake Forest IL
Allan C. Krueger - Gurnee IL
Zhen Lin - Gurnee IL
Darold L. Madigan - Elk Grove Village IL
Keith F. McDaniel - Wauconda IL
Steven W. Muchmore - Libertyville IL
Hing L. Sham - Mundelein IL
Kent D. Stewart - Gurnee IL
Vincent S. Stoll - Libertyville IL
Minghua Sun - Libertyville IL
Noah P. Tu - Gurnee IL
Frank L. Wagenaar - Gurnee IL
Gary T. Wang - Niles IL
Sheldon Wang - Grayslake IL
Paul E. Wiedeman - Deerfield IL
Yibo Xu - New Milford CT
Ming C. Yeung - Grayslake IL
Chen Zhao - Libertyville IL
Stephen Hanessian - Beaconsfield, CA
Malken Bayrakdarian - Verdun, CA
Xuehong Luo - Montreal, CA

Assignee:

Abbott Laboratories - Abbott Park IL

International Classification:

A61K 3140

US Classification:

514423

Abstract:

Disclosed are compounds of the formula: which are useful for inhibiting neuraminidases from disease-causing microorganisms, especially, influenza neuraminidase. Also disclosed are compositions and methods for preventing and treating diseases caused by microorganisms having a neuraminidase, processes for preparing the compounds and synthetic intermediates used in these processes.

US Patent:

20200209250, Jul 2, 2020

Filed:

Dec 27, 2019

Appl. No.:

16/729067

Inventors:

- Abbott Park IL, US
Patrick J. Macdonald - Abbott Park IL, US
Kerry M. Swift - Abbott Park US, US
Sergey Y. Tetin - Abbott Park IL, US
Brenda Calfin - Abbott Park IL, US
Zhen Lin - Abbott Park IL, US
Richard Haack - Abbott Park IL, US
Mark R. Pope - Abbott Park IL, US
John Prostko - Abbott Park IL, US
Xiaoxing Qiu - Abbott Park IL, US
Felicia Bogdan - Abbott Park IL, US

International Classification:

G01N 33/58
G01N 15/14
G01N 33/543

Abstract:

The disclosure provides methods of analyzing an analyte of interest in a biological sample using fluorescent agents and macroconjugates which comprise a core containing a cross-linked polymer or protein, tags, specific binding members or fragments thereof, and optionally carrier proteins. Also provided are methods of analyzing two or more analytes of interest in a biological sample in a single assay using microparticles and detection conjugates comprising different fluorophore labels, acquiring transmitted light and fluorescent images of the microparticles, and using a customized image analysis process to analyze the acquired images.