Zhi Qiang Zheng

US Patent:

20170275684, Sep 28, 2017

Filed:

Sep 4, 2015

Appl. No.:

15/508861

Inventors:

Zhi ZHENG - Fullerton CA, US

International Classification:

C12Q 1/68

Abstract:

The present application provides simple, specific and sensitive methods for detecting a target nucleic acid in a biological sample, detecting a pathogen in a biological sample, and diagnosing a disease in an individual, utilizing a combination of nucleic acid hybridization-based capture and ligation-enabled PCR. The methods are particularly useful for detecting low level nucleic acids and pathogens and for automation and processing of multiple biological samples.