Zhiqiang Chen

US Patent:

20170042985, Feb 16, 2017

Filed:

Apr 22, 2015

Appl. No.:

15/305719

Inventors:

- Houston TX, US
Lei ZHOU - Houston TX, US
Peter VANDERSLICE - Houston TX, US
Ke-He RUAN - Bellaire TX, US
Zhiqiang CHEN - Houston TX, US

International Classification:

A61K 38/54
A61K 38/44
A61K 48/00
A61K 38/52

Abstract:

An effective amount of a composition comprising (i) a plasmid having a cyclooxygenase-prostacyclin synthase fusion gene, and (ii) a carrier fluid for use in treating an individual having a vascular disease or at risk of developing a vascular disease. A composition comprising a carrier fluid; and a DNA sequence encoding for a triple catalytic enzyme, a cDNA sequence encoding for a triple catalytic enzyme, a plasmid comprising a DNA sequence encoding for a triple catalytic enzyme, a fusion gene encoding for a triple catalytic enzyme, a cyclooxygenase-prostacyclin synthase fusion gene, or combinations thereof, for use in treating an individual having a vascular disease or at risk of developing a vascular disease.