Zhong Xiong Chen

age ~51

from Philadelphia, PA

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Zhong Chen Phones & Addresses

Pyrrolopyridazine Compounds And Methods Of Use Thereof For The Treatment Of Proliferative Disorders
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US Patent:

6900208, May 31, 2005
Filed:

Mar 25, 2003
Appl. No.:

10/396197
Inventors:

Mark Salvati - Lawrenceville NJ, US
Stephanie A. Barbosa - Lambertville NJ, US
Zhong Chen - Cranbury NJ, US
John T. Hunt - Princeton NJ, US
Assignee:

Bristol Myers Squibb Company - Princeton NJ
International Classification:

C07D487/04
C07D487/14
A61K031/5025
A61P005/28
A61P035/00
US Classification:

514248, 544235
Abstract:

Disclosed are pyrrolopyridazine compounds of the formula,.

Pyrrolotriazine Kinase Inhibitors
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US Patent:

7173031, Feb 6, 2007
Filed:

Jun 24, 2005
Appl. No.:

11/167049
Inventors:

Robert M. Borzilleri - New Hope PA, US
Zhong Chen - Princeton NJ, US
John T. Hunt - Princeton NJ, US
Tram Huynh - Pennington NJ, US
Michael A. Poss - Lawrenceville NJ, US
Gretchen M. Schroeder - Ewing NJ, US
Wayne Vaccaro - Yardley PA, US
Tai W. Wong - Belle Mead NJ, US
Kyoung S. Kim - North Brunswick NJ, US
Assignee:

Bristol-Myers Squibb Company - Princeton NJ
International Classification:

C07D 487/04
C07D 401/02
A61K 31/53
A61P 35/00
US Classification:

514243, 544183
Abstract:

In general, the instant invention comprises compounds of Formulas I and II.

Fused Heterocyclic Kinase Inhibitors
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US Patent:

7439246, Oct 21, 2008
Filed:

Dec 1, 2005
Appl. No.:

11/292358
Inventors:

Robert M. Borzilleri - New Hope PA, US
Zhong Chen - Princeton NJ, US
Tram N. Huynh - Pennington NJ, US
Wayne Vaccaro - Yardley PA, US
Kyoung S. Kim - North Brunswick NJ, US
Assignee:

Bristol-Myers Squibb Company - Princeton NJ
International Classification:

C07D 471/02
A61K 31/519
US Classification:

5142581, 5142591, 5142621, 5142651, 514300, 514303, 544253, 544255, 544262, 546113, 546114, 546115, 546118
Abstract:

In general, the instant invention comprises compounds of Formulas I and II.

Fused Heterocyclic Compounds Useful As Kinase Modulators
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US Patent:

7723336, May 25, 2010
Filed:

Mar 21, 2007
Appl. No.:

11/689132
Inventors:

Wayne Vaccaro - Yardley PA, US
Zhong Chen - Princeton NJ, US
Dharmpal S. Dodd - Princeton NJ, US
Tram N. Huynh - Pennington NJ, US
James Lin - Lawrenceville NJ, US
Chunjian Liu - Pennington NJ, US
Christopher P. Mussari - Princeton NJ, US
John S. Tokarski - Princeton NJ, US
David R. Tortolani - Skillman NJ, US
Stephen T. Wrobleski - Whitehouse Station NJ, US
Shuqun Lin - Newtown PA, US
Assignee:

Bristol-Myers Squibb Company - Princeton NJ
International Classification:

C07D 487/04
A61K 31/5025
A61P 19/02
US Classification:

514248, 544236
Abstract:

Compounds having the formula (I), and enantiomers, and diastereomers, pharmaceutically-acceptable salts, thereof,.

Bifunctional Glycopeptide Antibiotics And Combinatorial Libararies Thereof
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US Patent:

20030158093, Aug 21, 2003
Filed:

Aug 19, 2002
Appl. No.:

10/223569
Inventors:

Binyuan Sun - Princeton NJ, US
Zhong Chen - Princeton NJ, US
Daniel Kahne - Princeton NJ, US
International Classification:

A61K038/14
C07K009/00
US Classification:

514/008000, 530/322000
Abstract:

The present invention relates to a the design of a large class of antibiotics comprised of aglycones of vancomycin or derivatives of an aglycone of vancomycin attached to the anomeric site of moenomycin or a moenomycin derivative.

Pyrrolopyridazine Compounds And Methods Of Use Thereof For The Treatment Of Proliferative Disorders
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US Patent:

20050159420, Jul 21, 2005
Filed:

Jan 5, 2005
Appl. No.:

11/029547
Inventors:

Mark Salvati - Lawrenceville NJ, US
Stephanie Barbosa - Lambertville NJ, US
Zhong Chen - Cranbury NJ, US
John Hunt - Princeton NJ, US
International Classification:

A61K031/503
C07D487/04
US Classification:

514248000, 544235000
Abstract:

Disclosed are pyrrolopyridazine compounds, methods of preparing such compounds, and their use for the treatment of proliferative, inflammatory, and other disorders.

Fused Heterocyclic Kinase Inhibitors
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US Patent:

20050288290, Dec 29, 2005
Filed:

Jun 24, 2005
Appl. No.:

11/167043
Inventors:

Robert Borzilleri - New Hope PA, US
Zhong Chen - Princeton NJ, US
Tram Huynh - Pennington NJ, US
Wayne Vaccaro - Yardley PA, US
Kyoung Kim - North Brunswick NJ, US
International Classification:

A61K031/53
A61K031/52
A61K031/519
C07D473/14
C07D487/02
US Classification:

514243000, 514261100, 514263220, 544277000, 544183000, 544254000
Abstract:

In general, the instant invention comprises compounds of Formulas I and II including pharmaceutically acceptable salts thereof. The compounds of the invention are useful as protein kinase inhibitors and therefore are useful for treating cancer and other protein kinase mediated diseases.

Inhibitors Of Protein Arginine Methyl Transferases
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US Patent:

20070060589, Mar 15, 2007
Filed:

Dec 20, 2005
Appl. No.:

11/312812
Inventors:

Ashok Purandare - Pennington NJ, US
Zhong Chen - Princeton NJ, US
International Classification:

A61K 31/506
A61K 31/501
A61K 31/497
A61K 31/4709
A61K 31/4545
A61K 31/454
C07D 417/02
C07D 413/02
C07D 403/02
US Classification:

514252050, 514310000, 514326000, 514255050, 514256000, 514318000, 544238000, 544333000, 544405000, 546146000, 546194000, 546209000
Abstract:

A compound of formula I, or a stereoisomer, a tautomer, a pharmaceutically acceptable salt or solvate thereof, methods of using such compounds in the treatment of hyperproliferative, inflammatory, infectious, and immunoregulatory disorders and diseases; and to pharmaceutical compositions containing such compounds.