Zhong Zheng from Johnson City, TN, age 52

License #:

68329 - Expired

Category:

Engineers

Issued Date:

Jul 25, 2008

Effective Date:

Mar 14, 2017

Expiration Date:

Feb 28, 2017

Type:

Professional Engineer

Substituted Urea Depsipeptide Analogs As Activators Of The Clpp Endopeptidase
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US Patent:

20200270311, Aug 27, 2020
Filed:

May 8, 2020
Appl. No.:

16/870648
Inventors:

- Memphis TN, US
Ying Zhao - Memphis TN, US
Elizabeth Griffith - Germantown TN, US
Zhong Zheng - Irvine CA, US
Aman P. Singh - Memphis TN, US
International Classification:

C07K 11/02
A61K 38/15
A61K 45/06
C12N 9/50
C07K 7/06
Abstract:

In one aspect, the invention relates to substituted urea depsipeptide analogs, derivatives thereof, and related compounds, which are useful as activators the ClpP endopeptidease; synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating infectious disease using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Substituted Urea Depsipeptide Analogs As Activators Of The Clpp Endopeptidase
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US Patent:

20180127469, May 10, 2018
Filed:

Jan 5, 2018
Appl. No.:

15/863673
Inventors:

- Memphis TN, US
Ying Zhao - Memphis TN, US
Elizabeth Griffith - Germantown TN, US
Zhong Zheng - Irvine CA, US
Aman P. Singh - Memphis TN, US
International Classification:

C07K 11/02
C07K 7/06
A61K 38/15
C12N 9/50
A61K 45/06
A61K 38/00
Abstract:

In one aspect, the invention relates to substituted urea depsipeptide analogs, derivatives thereof, and related compounds, which are useful as activators the ClpP endopeptidease; synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating infectious disease using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Aryl Substituted Aminomethyl Spectinomycin Analogs As Antibacterial Agents
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US Patent:

20160347762, Dec 1, 2016
Filed:

Sep 29, 2014
Appl. No.:

15/024549
Inventors:

- Memphis TN, US
Samanthi L. Waidyarachchi - Southaven MS, US
David F. Bruhn - Memphis TN, US
Zhong Zheng - Irvine CA, US
Jason W. Rosch - Memphis TN, US
Assignee:

ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. - Memphis TN
International Classification:

C07D 493/04
A61K 45/06
A61K 9/00
A61K 31/4433
A61K 31/381
A61K 31/497
A61K 31/4178
A61K 31/428
A61K 31/4045
A61K 31/4025
A61K 31/5377
A61K 31/357
A61K 31/427
Abstract:

The invention relates to aryl substituted aminomethyl spectinomycin analogs, derivatives thereof, and related compounds, which are useful as anti-bacterial agents; methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating anti-bacterial infections using the compounds and compositions.

Substituted Urea Depsipeptide Analogs As Activators Of The Clpp Endopeptidase
view source
US Patent:

20160200770, Jul 14, 2016
Filed:

Aug 30, 2014
Appl. No.:

14/914449
Inventors:

- Memphis TN, US
Ying Zhao - Memphis TN, US
Elizabeth Griffith - Germantown TN, US
Zhong Zheng - Irvine CA, US
Aman P. Singh - Memphis TN, US
International Classification:

C07K 11/02
A61K 45/06
C12N 9/50
A61K 38/15
Abstract:

In one aspect, the invention relates to substituted urea depsipeptide analogs, derivatives thereof, and related compounds, which are useful as activators the ClpP endopeptidease; synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating infectious disease using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.