- Rockville MD, US Ye Liu - Clarksville MD, US Andrew Mercer - Poolesville MD, US Samantha Yost - Rockville MD, US Elad Firnberg - Baltimore MD, US
International Classification:
C12N 15/86 C07K 14/005
Abstract:
The present invention relates to recombinant adeno-associated viruses (rAAVs) having capsid proteins engineered to include amino acid sequences that confer and/or enhance desired properties. In particular, the invention provides engineered capsid proteins comprising peptide insertions from heterologous proteins inserted within or near variable region IV (VR-IV) of the virus capsid, such that the insertion is surface exposed on the AAV particle. The invention also provides capsid proteins that direct rAAVs to target tissues, in particular, capsid proteins comprising peptides derived from erythropoietin or dynein that are inserted into surface-exposed variable regions and that target rAAVs to retinal tissue and/or neural tissue, including the central nervous system, and deliver therapeutics for treating neurological and/or eye disorders.
Maplewood Elementary School Lansing MI 1985-1991, Gardner Middle School Lansing MI 1991-1991, Hope Middle School Holt MI 1991-1993, Holt Junior High School Holt MI 1993-1995
Aaron Vann, Holly Hyden, Lori Herrmann, G Reed, Omari Shabani, Amanda Kuenstler, Christopher Rosales, Chris Mun, Brantley Hickerson, Jennifer Ayers, Kathy Bullin
Austin Elementary School Memphis TX 1985-1987, Travis Elementary School Memphis TX 1985-1987, Jackling Elementary School West Valley UT 1986-1988, Hillsdale Elementary School West Valley UT 1988-1990, Platt Elementary School Haughton LA 1990-1991, Princeton Junior High School Princeton LA 1991-1994
Community:
Renee Phillips, Jessica Lewis, Renessia Lars, Rebekah Morris, Kelly Craft, Jason Farrington, Shantee Venious
The study, touted as "one of the largest ever conducted with a nationally representative sample of police," and authored by Rich Morin, Kim Parker, Renee Stepler and Andrew Mercer, comprised the responses of nearly 8,000 U.S. officers, the research organization said.
Date: Jan 12, 2017
Category: U.S.
Source: Google
HUFFPOLLSTER: Here's What We Know About Why Polling Missed The Mark
-Andrew Mercer, Claudia Deane and Kyley McGeeney: Across the board, polls underestimated Trumps level of support....The fact that so many forecasts were off-target was particularly notable given the increasingly wide variety of methodologies being tested and reported via the mainstream media and o
Commercial Director at Eurostar Past: Director at Intramezzo, Marketing Director at Misys, Marketing Director at British... Board Director with extensive international commercial business experience in consumer services. Have worked across a wide range of market sectors ranging from... Board Director with extensive international commercial business experience in consumer services. Have worked across a wide range of market sectors ranging from travel, financial services to internet and digital TV.
Have a various stages in my career been responsible for markets such as Japan, the...