Taste receptor PC-1-L3/PC-2-L1 is provided. Methods and systems for screening for tastants and receptor modulators are provided. Knock out and transgenic animals, methods of detecting polymorphisms, and methods of correcting taste defects are also provided.
This invention provides biosensors, cell models, and methods of their use for monitoring chloride ion, where the biosensors can include targeting domains, sensing domains and reporting domains. Biosensors can be introduced into cells reprogrammed to represent experimental or pathologic cells of interest, including as detectors of chloride ions, as TempoChloro™ accomplishes.
This invention provides biosensors, cell models, and methods of their use for monitoring osmolarity. Biosensors can include targeting domains, sensing domains and reporting domains. Biosensors can be introduced into cells reprogrammed to represent experimental or pathologic cells of interest. Model cells expressing the biosensors can be contacted with putative bioactive agents to determine possible activities, including as detectors of which is pH changes, as TempoOsmo™ accomplishes.
This invention provides biosensors, cell models, and methods of their use for monitoring heme and oxygen. Biosensors can include targeting domains, sensing domains and reporting domains. Biosensors can be introduced into cells reprogrammed to represent experimental or pathologic cells of interest. Model cells expressing the biosensors can be contacted with putative bioactive agents to determine possible activities.
- San Fransisco CA, US Angela Huang - San Mateo CA, US
International Classification:
G01N 33/68 C07K 14/705 G01N 33/58 C12N 15/85
Abstract:
This invention provides biosensors, cell models, and methods of their use for monitoring heme, oxygen or ATP. Biosensors can include targeting domains, sensing domains and reporting domains. Biosensors can be introduced into cells reprogrammed to represent experimental or pathologic cells of interest. Model cells expressing the biosensors can be contacted with putative bioactive agents to determine possible activities.
This invention provides biosensors, cell models, and methods of their use for monitoring heme, oxygen or ATP. Biosensors can include targeting domains, sensing domains and reporting domains. Biosensors can be introduced into cells reprogrammed to represent experimental or pathologic cells of interest. Model cells expressing the biosensors can be contacted with putative bioactive agents to determine possible activities.
This invention provides biosensors, cell models, and methods of their use for monitoring heme, oxygen or ATP. Biosensors can include targeting domains, sensing domains and reporting domains. Biosensors can be introduced into cells reprogrammed to represent experimental or pathologic cells of interest. Model cells expressing the biosensors can be contacted with putative bioactive agents to determine possible activities.
This invention provides biosensors, cell models, and methods of their use for monitoring ionic or voltage responses to contact with bioactive agents. Biosensors can include targeting domains, sensing domains and reporting domains. Biosensors can be introduced into cells reprogrammed to represent experimental or pathologic cells of interest. Model cells expressing the biosensors can be contacted with putative bioactive agents to determine possible activities.
Medicine Doctors
Angela C Huang, Milpitas CA - OD (Doctor of Optometry)
Dr. Huang graduated from the UMDNJ New Jersey Medical School at Newark in 2002. She works in Amarillo, TX and specializes in Developmental-Behavioral Pediatrics. Dr. Huang is affiliated with BSA Hospital and The Pavilion Northwest Texas Healthcare System.
Adecco Group at Google Mountain View, CA May 2013 to May 2014 Legal AssistantGolden Bear Sleep and Mood Research Clinic Berkeley, CA May 2010 to May 2012 Research AssistantInstitute of Personality & Social Research Berkeley, CA May 2010 to Nov 2011 Research AssistantSleep and Neuroimaging Lab Berkeley, CA Aug 2010 to Aug 2011 Research AssistantAssociated Students of the University of California Berkeley, CA Aug 2010 to Dec 2010 Notes Taker
Education:
University of California, Berkeley Berkeley, CA 2007 to 2011 B.A. in EconomicsUniversity of California, Berkeley Berkeley, CA 2007 to 2011 B.A. in Psychology
Bain & Company China, ME 2008 to 2013 ManagerTrianz Consulting Silicon Valley, CA 2005 to 2007 Senior ConsultantAPL Logistics Oakland, CA Aug 2002 to Feb 2005 Logistics EngineerAPL Logistics
2002 to 2005 American President Line
Education:
INSEAD 2007 to 2008 MBAUniversity of California at Berkeley Berkeley, CA 2000 to 2002 Bachelor of Science in Business Administration
Westview Elementary School Apple Valley MN 1980-1983, Valley Middle School Apple Valley MN 1983-1985, Ben Eielson Junior Senior High School Eielson Afb AK 1985-1986
Naperville North High School Naperville IL 1993-1997
Community:
Christina Slaughter, Stefanie Kunze, David Vrbenec, Chris Shales, John Dickerson, David Aronson, Kamai Westbrooks, Ed Marshinski, Jennifer Risvold, Jeremy Rosenfeld