Antonio Ml Possolo

US Patent:

20060216718, Sep 28, 2006

Filed:

Mar 23, 2005

Appl. No.:

11/087482

Inventors:

Antonio Possolo - Niskayuna NY, US
Jay Silkworth - Schodack Landing NY, US
Kati Illouz - Schenectady NY, US

International Classification:

C12Q 1/68
G06F 19/00

US Classification:

435006000, 702020000

Abstract:

A method and system are provided for measuring differential gene expression that is induced on multiple experimental subjects by controlled, multiple experimental factors, measured using microarrays or other devices that measure the activity of multiple probes per gene. The information in the readings made from all the probes in the microarrays or other devices that received the experimental samples is extracted simultaneously, without prior summarization or aggregation at the gene level, by employing a multi-factor model that explicitly accounts for differences in expression between genes, between probes from the same gene, and between the effects of the experimental factors.

US Patent:

20050261998, Nov 24, 2005

Filed:

May 19, 2004

Appl. No.:

10/849480

Inventors:

Antonio Possolo - Niskayuna NY, US
Brock Osborn - Niskayuna NY, US
Kathleen Skumurski - Clifton Park NY, US
Mariano Weil - Waterbury CT, US
Mitchell Danaher - Trumbull CT, US

International Classification:

G06F017/60

US Classification:

705035000

Abstract:

Computer system and method for performing valuation of stock options issued by a corporation to employees are provided. The computer system may comprise a historical employee stock option database populated with information regarding employee stock option awards issued by said corporation. The computer system may further comprise a historical stock price database populated with historical stock prices and dividends, if any, issued by that corporation. An employee database may be populated with information regarding employees who have been issued stock options. A first data feed may provide present stock prices of the corporation. A second data feed may provide present risk-free interest rate structure. A processor may be configured to extract from data stored in the databases at least one historical-based parameter affecting a valuation of employee stock options. A user interface may be used for communicating with the processor and perform a valuation of employee stock options at least in part based on the at least one historical-based parameter.