Babak Borhan from 1411 Weatherhill Ct, East Lansing, MI 48823, age 59, Phone: (517)7632431

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Location:

East Lansing, MI

Industry:

Higher Education

Work:

Michigan State University
Asc Professor Chemistry

Catalytic Osmium-Assisted Oxidative Cleavage Of Olefins
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US Patent:

6787671, Sep 7, 2004
Filed:

Jan 13, 2003
Appl. No.:

10/341499
Inventors:

Babak Borhan - East Lansing MI
Benjamin R. Travis - Lansing MI
Jennifer M. Schomaker - Mt. Pleasant MI
Assignee:

Board of Trustees of Michigan State University - East Lansing MI
International Classification:

C07C 4500
US Classification:

568314, 568317, 568356, 568398, 568430, 568435, 568485, 5625122, 562521, 562531, 562535, 560114, 560115, 560207, 560210
Abstract:

An osmium-assisted process for the oxidative cleavage of oxidizable organic compounds such as unsaturated organic compounds, including alkenes and olefins into aldehydes, carboxylic acids, esters, or ketones. The process uses a metal catalyst comprising osmium and a peroxy compound selected from the group consisting of peroxymonosulfuric acid and salts thereof to oxidatively cleave the oxidizable organic compound. In particular, the process enables aldehydes, carboxylic acids, esters, or ketones to be selectively produced from the corresponding mono-, 1,1-di-, 1,2-di-, tri-, or tetra-substituted olefins in a reaction that produces the result of ozonolysis but with fewer problems. The present invention further provides a process for oxidizing an aldehyde alone or with the osmium in an interactive solvent to produce an ester or carboxylic acid.

Inhibitors Of Epoxide Hydrolases For The Treatment Of Inflammation
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US Patent:

20070117782, May 24, 2007
Filed:

Dec 1, 2006
Appl. No.:

11/566171
Inventors:

Bruce Hammock - Davis CA, US
Jiang Zheng - Seattle WA, US
Christophe Morisseau - Davis CA, US
Kazuhiko Motoba - Kawachinagano, JP
Mehran Moghaddam - San Diego CA, US
Babak Borhan - East Lansing MI, US
David Grant - Storrs CT, US
Jessica Greene - Oakland CA, US
Marlene Sisemore - Davis CA, US
James Sanborn - Sacramento CA, US
Assignee:

The Regents of the University of California - Oakland CA
International Classification:

A61K 31/66
A61K 31/17
US Classification:

514114000, 514580000, 514588000
Abstract:

The invention provides compounds that inhibit epoxide hydrolase in therapeutic applications for treating hypertension. A preferred class of compounds for practicing the invention have the structure shown by Formula 1 wherein Z is oxygen or sulfur, W is carbon phosphorous or sulfur, X and Y is each independently nitrogen, oxygen, or sulfur, and X can further be carbon, at least one of R-Ris hydrogen, Ris hydrogen when X is nitrogen but is not present when X is sulfur or oxygen, Ris hydrogen when Y is nitrogen but is not present when Y is sulfur or oxygen, Rand Ris each independently C-Csubstituted or unsubstituted alkyl, cycloalkyl, aryl, acyl, or heterocyclic.

Synthesis Of N-Heterocycles, Beta-Amino Acids, And Allyl Amines Via Aza-Payne Mediated Reaction Of Ylides And Hydroxy Aziridines
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US Patent:

20090012120, Jan 8, 2009
Filed:

May 9, 2007
Appl. No.:

11/801395
Inventors:

Babak Borhan - East Lansing MI, US
Jennifer M. Schomaker - Berkeley CA, US
Somnath Bhattacharjee - East Lansing MI, US
Keith Korthals - East Lansing MI, US
Assignee:

Board of Trustees of Michigan State University - East Lansing MI
International Classification:

A61K 31/4015
C07D 207/12
C07D 209/32
C07D 209/54
C07C 211/00
C07D 211/00
A61P 35/00
A61K 31/13
A61K 31/403
A61K 31/445
US Classification:

514315, 548556, 548541, 548512, 548408, 564463, 546184, 514579, 514409, 514412, 514424
Abstract:

An ylide-based aza-Payne rearrangement of 2,3-aziridin--ols leads to an efficient process for the preparation of pyrrolidines. The aza-Payne rearrangement under the basic reaction conditions favors the formation of epoxy amines. Subsequent nucleophilic attack of the epoxide by the ylide yields a bis-anion, which upon a 5-exo-tet ring closure yields the desired pyrrolidine, thus completing the relay of the 3-membered the 5-membered nitrogen containing ring system. This process takes place with complete transfer of stereochemical fidelity, and can be applied to sterically hindered aziridinols.

Colorimetric And Fluorescent Proteins
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US Patent:

20130157284, Jun 20, 2013
Filed:

Mar 23, 2011
Appl. No.:

13/636499
Inventors:

Babak Borhan - Okemos MI, US
James Geiger - Webberville MI, US
Wenjing Wang - Cambridge MA, US
Chrysoula Vasileiou - East Langsing MI, US
Kin Sing Lee - Davis CA, US
Tetyana Berbasova - East Lansing MI, US
Assignee:

Board of Trustees of Michigan State University - East Lansing MI
International Classification:

C07K 14/47
G01N 33/58
US Classification:

435 71, 536 235, 536 234, 4353201, 4352523, 43525411, 4352542, 435325, 435348, 435419, 43525233, 43525231, 43525235, 43525234, 435365, 435358, 435357, 435367, 435352, 43525421, 43525423, 4352543, 4352546, 435370, 435366, 530350, 530410, 530409, 4352831
Abstract:

The invention relates to intracellular lipid binding proteins that bind retinoids and/or dye ligands and that are modified to transmit or emit light at a variety of different wavelengths.

High-Performance Near-Infrared Harvesting Transparent Luminescent Solar Concentrators
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US Patent:

20230033629, Feb 2, 2023
Filed:

Jul 18, 2022
Appl. No.:

17/867022
Inventors:

- , US
Chenchen YANG - Holt MI, US
Babak BORHAN - Okemos MI, US
Mehdi MOEMENI - Okemos MI, US
Matthew BATES - East Lansing MI, US
Assignee:

Board of Trustees of Michigan State University - East Lansing MI
International Classification:

H01L 31/055
H01L 31/048
H01L 31/054
Abstract:

A transparent luminescent solar concentrator (TLSC) is provided. The TLSC includes a luminophore and a waveguide that guides light emitted from the luminophore. The TLSC has a light utilization efficiency (LUE) of greater than or equal to about 1.

Babak Borhan