Cheng Guo

US Patent:

8183275, May 22, 2012

Filed:

Oct 16, 2007

Appl. No.:

12/311672

Inventors:

Peter H. Dobbelaar - Morris Plains NJ, US
Christopher L. Franklin - Keasbey NJ, US
Allan Goodman - Media PA, US
Cheng Guo - Schenectady NY, US
Peter R. Guzzo - Niskayuna NY, US
Mark Hadden - Albany NY, US
Shuwen He - Edison NJ, US
Alan J. Henderson - Albany NY, US
Tianying Jian - Westfield NJ, US
Linus S. Lin - Westfield NJ, US
Jian Liu - Edison NJ, US
Ravi P. Nargund - East Brunswick NJ, US
Megan Ruenz - Grayslake IL, US
Bruce J. Sargent - Delmar NY, US
Iyassu K. Sebhat - Jersey City NJ, US
Larry Yet - Albany NY, US

Assignee:

Merck Sharp & Dohme Corp. - Rahway NJ
Albany Molecular Research, Inc. - Albany NY

International Classification:

A61K 31/4178
A61K 31/4164
C07D 471/04
C07D 401/10
C07D 403/10
C07D 233/64

US Classification:

514393, 514360, 514385, 514387, 514390, 548126, 5483001, 548416, 548578, 546113, 5462727, 544333, 544405

Abstract:

Certain novel substituted imidazoles are ligands of the human bombesin receptor and, in particular, are selective ligands of the human bombesin receptor subtype-3 (BRS-3). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the modulation of BRS-3, such as obesity, and diabetes.

US Patent:

57051038, Jan 6, 1998

Filed:

Nov 22, 1996

Appl. No.:

8/755131

Inventors:

Vilas M. Chopdekar - Edison NJ
James R. Schleck - Somerset NJ
Cheng Guo - Harrison NJ
Amanda J. Hall - Raritan NJ

Assignee:

Jame Fine Chemicals, Inc. - Bound Brook NJ

International Classification:

C09K 300

US Classification:

252700

Abstract:

A chemiluminescent composition comprising an oxalate component comprising polystyrene or homopoly-. alpha. -methylstyrene containing an oxalate ester; an activator component comprising a solution of a peroxide compound and a catalyst in a first solvent; and a fluorescer contained in the oxalate component, activator component, or in both the oxalate component and the activator component. The first solvent is preferably a propylene glycol dialkyl ether. The chemiluminescent composition, when activated, permits light to be produced of controllable duration.

US Patent:

56634153, Sep 2, 1997

Filed:

Jun 28, 1996

Appl. No.:

8/671604

Inventors:

Vilas M. Chopdekar - Edison NJ
James R. Schleck - Somerset NJ
Vernon A. Brown - Maplewood NJ
Cheng Guo - Harrison NJ

Assignee:

Jame Fine Chemicals, Inc. - Bound Brook NJ

International Classification:

C07C 6988

US Classification:

560 68

Abstract:

A process for preparing pure antihistamine tannate compositions. The antihistamine in the form of its free base is contacted with tannic acid in the presence of water for a period of time of about 5 minutes to 4 hours and at a maximum temperature such that not more than about 5 wt. % of the antihistamine tannate will be decomposed. Water is removed from the antihistamine tannate by freeze-drying.

US Patent:

55975178, Jan 28, 1997

Filed:

Apr 30, 1996

Appl. No.:

8/640069

Inventors:

Vilas M. Chopdekar - Edison NJ
James R. Schleck - Somerset NJ
Cheng Guo - Harrison NJ
Amanda J. Hall - Raritan NJ

Assignee:

Jame Fine Chemicals, Inc. - Bound Brook NJ

International Classification:

C09K 300

US Classification:

252700

Abstract:

A chemiluminescent composition comprising an oxalate component comprising an oxalate ester and a solvent, an activator component comprising a peroxide compound and a catalyst and a fluorescer contained in the oxalate component and/or the activator component. The solvent contained in the oxalate component comprises a propylene glycol dihydrocarbyl ether containing one to three propylene moieties and each hydrocarbyl moiety contains up to 8 carbon atoms and is independently selected from the group consisting of straight chain alkyl, branched chain alkyl, cycloalkyl, aryl, alkaryl and aralkyl groups.

US Patent:

55998461, Feb 4, 1997

Filed:

Jun 28, 1996

Appl. No.:

8/671160

Inventors:

Vilas M. Chopdekar - Edison NJ
James R. Schleck - Somerset NJ
Vernon A. Brown - Maplewood NJ
Cheng Guo - Harrison NJ

Assignee:

Jame Fine Chemicals, Inc. - Bound Brook NJ

International Classification:

A61K 31135

US Classification:

514653

Abstract:

Phenylephrine tannate compositions are disclosed wherein the phenylephrine tannate has a minimum purity level of at least 95%. The composition also contains a minor amount of water, but no significant quantities of organic compounds or solvents other than water are present. The phenylephrine tannate will have a density of at least 0. 6 g/cc.

US Patent:

20220411860, Dec 29, 2022

Filed:

Jul 12, 2021

Appl. No.:

17/373295

Inventors:

Jingyue Ju - Englewood Cliffs NJ, US
Xiaoxu Li - New York NY, US
Xin Chen - New York NY, US
Zengmin Li - Flushing NY, US
Shiv Kumar - Belle Meade NJ, US
Shundi Shi - Ozone Park NY, US
Cheng Guo - Brooklyn NY, US
Jianyi Ren - New York NY, US
Minchen Chien - Tenafly NJ, US
Chuanjuan Tao - Fort Lee NJ, US
Ece Erturk - New York NY, US
Sergey Kalachikov - Bronx NY, US
James J. Russo - New York NY, US

Assignee:

The Trustees of Columbia University in the City of New York - New York NY

International Classification:

C12Q 1/6869
C07H 19/10
C07H 19/14
C07H 19/20

Abstract:

Disclosed herein, inter alfa, are compounds, compositions, and methods of use thereof in the sequencing of a nucleic acid.

US Patent:

20230028321, Jan 26, 2023

Filed:

Mar 7, 2022

Appl. No.:

17/688752

Inventors:

- New York NY, US
Xin Chen - Changsha, CN
Xiaoxu Li - New York NY, US
Zengmin Li - Flushing NY, US
Minchen Chien - Tenafly NJ, US
Shundi Shi - Ozone Park NY, US
Jianyi Ren - Rosemead CA, US
Cheng Guo - Brooklyn NY, US
Shiv Kumar - Belle Mead NJ, US
James Russo - New York NY, US
Chuanjuan Tao - Fort Lee NJ, US
Steffen Jockusch - New York NY, US
Sergey Kalachikov - Bronx NY, US

Assignee:

The Trustees of Columbia University in the City of New York - New York NY

International Classification:

A61K 31/7052
C07H 21/04

Abstract:

Disclosed herein, inter alia, are compounds, compositions, and methods of use thereof in the sequencing a nucleic acid.

US Patent:

20230028388, Jan 26, 2023

Filed:

Aug 1, 2022

Appl. No.:

17/816555

Inventors:

- New York NY, US
Xiaoxu Li - New York NY, US
Xin Chen - New York NY, US
Zengmin Li - Flushing NY, US
Shiv Kumar - Belle Meade NJ, US
Shundi Shi - Ozone Park NY, US
Cheng Guo - Brooklyn NY, US
Jianyi Ren - New York NY, US
Minchen Chien - Tenafly NJ, US
Chuanjuan Tao - Fort Lee NJ, US
Ece Erturk - New York NY, US
Sergey Kalachikov - Bronx NY, US
James J. Russo - New York NY, US

Assignee:

The Trustees of Columbia University in the City of New York - New York NY

International Classification:

C12Q 1/6869
C07H 19/10
C07H 19/20
C07H 19/14

Abstract:

Disclosed herein, inter alia, are compounds, compositions, and methods of use thereof in the sequencing of a nucleic acid.