Christine Nhien Nguyen

US Patent:

6682559, Jan 27, 2004

Filed:

Jan 29, 2001

Appl. No.:

09/772526

Inventors:

Keith Myers - Lake Forest CA
Christine Nguyen - Garden Grove CA

Assignee:

3F Therapeutics, Inc. - Lake Forest CA

International Classification:

A61F 206

US Classification:

623 213, 623 212

Abstract:

A tubular prosthetic semilunar or atrioventricular heart valve is formed by cutting flat, flexible leaflets according to a pattern. The valve is constructed by aligning the side edges of adjacent leaflets so that the leaflet inner faces engage each other, and then suturing the leaflets together with successive stitches along a fold line adjacent the side edges. During operation, when the leaflets open and close, the leaflets fold along the fold line. Distal tabs extend beyond the distal end of each leaflet. The tab portions of adjacent leaflets are folded over each other and sewn together to form commissural attachment tabs. The commissural tabs provide commissural attachment points to accommodate sutures and the like in order to secure the tab to a vessel wall, if a semilunar valve, and papillary muscles and/or chordae tendineae, if an atrioventricular valve.

US Patent:

6911043, Jun 28, 2005

Filed:

Jan 5, 2004

Appl. No.:

10/751549

Inventors:

Keith Myers - Lake Forest CA, US
Christine Nguyen - Garden Grove CA, US

Assignee:

3F Therapeutics, Inc. - Lake Forest CA

International Classification:

A61F002/06

US Classification:

623 213, 623 21

Abstract:

A tubular prosthetic semilunar or atrioventricular heart valve is formed by cutting flat, flexible leaflets according to a pattern. The valve is constructed by aligning the side edges of adjacent leaflets so that the leaflet inner faces engage each other, and then suturing the leaflets together with successive stitches along a fold line adjacent the side edges. The stitches are placed successively from a proximal in-flow end of each leaflet toward a distal out-flow end. During operation, when the leaflets open and close, the leaflets fold along the fold line. Distal tabs extend beyond the distal end of each leaflet. The successive stitches terminate proximal of the distal tab portion so that no locked stitches are placed along the distal portion of the fold line. The tab portions of adjacent leaflets are folded over each other and sewn together to form commissural attachment tabs. The commissural tabs provide commissural attachment points to accommodate sutures and the like in order to secure the tab to a vessel wall, if a semilunar valve, and papillary muscles and/or chordae tendineae if an atrioventricular valve.

US Patent:

7037333, May 2, 2006

Filed:

Jan 5, 2004

Appl. No.:

10/751799

Inventors:

Keith Myers - Lake Forest CA, US
Christine Nguyen - Garden Grove CA, US

Assignee:

3F Therapeutics, Inc. - Lake Forest CA

International Classification:

A61F 2/06

US Classification:

623 213, 623 212

Abstract:

A tubular prosthetic semilunar or atrioventricular heart valve is formed by cutting flat, flexible leaflets according to a pattern. The valve is constructed by aligning the side edges of adjacent leaflets so that the leaflet inner faces engage each other, and then suturing the leaflets together with successive stitches along a fold line adjacent the side edges. The stitches are placed successively from a proximal in-flow end of each leaflet toward a distal out-flow end. During operation, when the leaflets open and close, the leaflets fold along the fold line. Distal tabs extend beyond the distal end of each leaflet. The successive stitches terminate proximal of the distal tab portion so that no locked stitches are placed along the distal portion of the fold line. The tab portions of adjacent leaflets are folded over each other and sewn together to form commissural attachment tabs. The commissural tabs provide commissural attachment points to accommodate sutures and the like in order to secure the tab to a vessel wall, if a semilunar valve, and papillary muscles and/or chordae tendineae if an atrioventricular valve.

US Patent:

20040117009, Jun 17, 2004

Filed:

Sep 23, 2003

Appl. No.:

10/668650

Inventors:

Douglas Cali - Mission Viejo CA, US
Keith Myers - Lake Forest CA, US
Brian Biancucci - Mission Viejo CA, US
Jason Artof - Huntington Beach CA, US
Christine Nguyen - Glendora CA, US
Rodolfo Quijano - Laguna Hills CA, US

International Classification:

A61F002/24

US Classification:

623/002120, 623/002130

Abstract:

An improved prosthetic mitral valve is provided having advantageous hemodynamic performance, nonthrombogenicity, and durability. The valve includes a valve body having an inflow annulus and an outflow annulus. Commissural attachment locations are disposed adjacent the outflow annulus. An anterior leaflet and a posterior leaflet of the valve are shaped differently from one another. The inflow annulus preferably is scalloped so as to have a saddle-shaped periphery having a pair of relatively high portions separated by a pair of relatively low portions. The anterior high portion preferably is vertically higher than the posterior high portion.

US Patent:

20070173932, Jul 26, 2007

Filed:

Dec 7, 2006

Appl. No.:

11/608098

Inventors:

Douglas Cali - Mission Viejo CA, US
Keith Myers - Lake Forest CA, US
Brian Biancucci - Mission Viejo CA, US
Jason Artof - Huntington Beach CA, US
Christine Nguyen - Glendora CA, US
Rodolfo Quijano - Laguna Hills CA, US

Assignee:

3F THERAPEUTICS, INC. - Lake Forest CA

International Classification:

A61F 2/24

US Classification:

623002130, 623901000, 623002120

Abstract:

An improved prosthetic mitral valve is provided having advantageous hemodynamic performance, nonthrombogenicity, and durability. The valve includes a valve body having an inflow annulus and an outflow annulus. Commissural attachment locations are disposed adjacent the outflow annulus. An anterior leaflet and a posterior leaflet of the valve are shaped differently from one another. The inflow annulus preferably is scalloped so as to have a saddle-shaped periphery having a pair of relatively high portions separated by a pair of relatively low portions. The anterior high portion preferably is vertically higher than the posterior high portion.

US Patent:

20090018655, Jan 15, 2009

Filed:

Jul 13, 2007

Appl. No.:

11/777733

Inventors:

John Brunelle - Newport Coast CA, US
Joshua Siegel - Exeter NH, US
Christine Nguyen - Glendora CA, US
Brenda Yantzer - Gainesville FL, US
Thomas Sander - Gainesville FL, US

International Classification:

A61F 2/08

US Classification:

623 1319, 623 1311

Abstract:

Disclosed are biocompatible implants that combine a scaffold material for supporting long term repair of a soft tissue with an elongated member such as a suture for aiding in placement of the scaffold during a surgical procedure as well as for immediate mechanical reinforcement of a repair site. The components of an implant are combined such that a longitudinal load placed upon a composite structure can be borne primarily by the elongated member and the scaffold material is isolated from the longitudinal load. Thus, the scaffold material of a composite can be protected from damage due to applied loads and stresses during and following a surgical procedure.

US Patent:

20210315692, Oct 14, 2021

Filed:

Jun 24, 2021

Appl. No.:

17/357816

Inventors:

- Irvine CA, US
Luca Pesce - Huntington Beach CA, US
Glen T. Rabito - Lake Forest CA, US
Christine Thanh Nguyen - Santa Ana CA, US

Assignee:

Edwards Lifesciences CardiAQ LLC - Irvine CA

International Classification:

A61F 2/24

Abstract:

A prosthesis for placement within a native heart valve preferably includes an expandable frame having locking tabs disposed along a proximal end. A plurality of distal anchors is disposed along a distal end of the frame. Each distal anchor is provided with a cushion cover. An outer fabric member surrounds the frame and may extend outwardly from the frame in an expanded condition for providing an improved seal in the region of a native annulus. A valve body is positioned within an interior of the expandable from for allowing blood flow in only one direction. In preferred embodiments, the cushions are positioned over enlarged head portions of the distal anchors for further reducing trauma on surrounding tissue.

US Patent:

20210038377, Feb 11, 2021

Filed:

Oct 28, 2020

Appl. No.:

17/083117

Inventors:

- Huntington Beach CA, US
John Paul USSIA - Huntington Beach CA, US
Christine Thanh NGUYEN - Huntington Beach CA, US
Christine Thao NGUYEN - Huntington Beach CA, US

International Classification:

A61F 2/24

Abstract:

Devices for assisting with the functioning of a tricuspid valve of a heart include a shaft, a flow optimizer, and an anchoring mechanism. A tilting mechanism can be configured to tilt the shaft relative to a central axis of the anchoring mechanism. Leaflets (e.g., multi-layer leaflets) of the flow optimizer can include a membrane and a rim, and the rim can have a higher stiffness than the membrane.