Christine Nguyen

US Patent:

6682559, Jan 27, 2004

Filed:

Jan 29, 2001

Appl. No.:

09/772526

Inventors:

Keith Myers - Lake Forest CA
Christine Nguyen - Garden Grove CA

Assignee:

3F Therapeutics, Inc. - Lake Forest CA

International Classification:

A61F 206

US Classification:

623 213, 623 212

Abstract:

A tubular prosthetic semilunar or atrioventricular heart valve is formed by cutting flat, flexible leaflets according to a pattern. The valve is constructed by aligning the side edges of adjacent leaflets so that the leaflet inner faces engage each other, and then suturing the leaflets together with successive stitches along a fold line adjacent the side edges. During operation, when the leaflets open and close, the leaflets fold along the fold line. Distal tabs extend beyond the distal end of each leaflet. The tab portions of adjacent leaflets are folded over each other and sewn together to form commissural attachment tabs. The commissural tabs provide commissural attachment points to accommodate sutures and the like in order to secure the tab to a vessel wall, if a semilunar valve, and papillary muscles and/or chordae tendineae, if an atrioventricular valve.

US Patent:

6911043, Jun 28, 2005

Filed:

Jan 5, 2004

Appl. No.:

10/751549

Inventors:

Keith Myers - Lake Forest CA, US
Christine Nguyen - Garden Grove CA, US

Assignee:

3F Therapeutics, Inc. - Lake Forest CA

International Classification:

A61F002/06

US Classification:

623 213, 623 21

Abstract:

A tubular prosthetic semilunar or atrioventricular heart valve is formed by cutting flat, flexible leaflets according to a pattern. The valve is constructed by aligning the side edges of adjacent leaflets so that the leaflet inner faces engage each other, and then suturing the leaflets together with successive stitches along a fold line adjacent the side edges. The stitches are placed successively from a proximal in-flow end of each leaflet toward a distal out-flow end. During operation, when the leaflets open and close, the leaflets fold along the fold line. Distal tabs extend beyond the distal end of each leaflet. The successive stitches terminate proximal of the distal tab portion so that no locked stitches are placed along the distal portion of the fold line. The tab portions of adjacent leaflets are folded over each other and sewn together to form commissural attachment tabs. The commissural tabs provide commissural attachment points to accommodate sutures and the like in order to secure the tab to a vessel wall, if a semilunar valve, and papillary muscles and/or chordae tendineae if an atrioventricular valve.

US Patent:

7037333, May 2, 2006

Filed:

Jan 5, 2004

Appl. No.:

10/751799

Inventors:

Keith Myers - Lake Forest CA, US
Christine Nguyen - Garden Grove CA, US

Assignee:

3F Therapeutics, Inc. - Lake Forest CA

International Classification:

A61F 2/06

US Classification:

623 213, 623 212

Abstract:

A tubular prosthetic semilunar or atrioventricular heart valve is formed by cutting flat, flexible leaflets according to a pattern. The valve is constructed by aligning the side edges of adjacent leaflets so that the leaflet inner faces engage each other, and then suturing the leaflets together with successive stitches along a fold line adjacent the side edges. The stitches are placed successively from a proximal in-flow end of each leaflet toward a distal out-flow end. During operation, when the leaflets open and close, the leaflets fold along the fold line. Distal tabs extend beyond the distal end of each leaflet. The successive stitches terminate proximal of the distal tab portion so that no locked stitches are placed along the distal portion of the fold line. The tab portions of adjacent leaflets are folded over each other and sewn together to form commissural attachment tabs. The commissural tabs provide commissural attachment points to accommodate sutures and the like in order to secure the tab to a vessel wall, if a semilunar valve, and papillary muscles and/or chordae tendineae if an atrioventricular valve.

US Patent:

20210315692, Oct 14, 2021

Filed:

Jun 24, 2021

Appl. No.:

17/357816

Inventors:

- Irvine CA, US
Luca Pesce - Huntington Beach CA, US
Glen T. Rabito - Lake Forest CA, US
Christine Thanh Nguyen - Santa Ana CA, US

Assignee:

Edwards Lifesciences CardiAQ LLC - Irvine CA

International Classification:

A61F 2/24

Abstract:

A prosthesis for placement within a native heart valve preferably includes an expandable frame having locking tabs disposed along a proximal end. A plurality of distal anchors is disposed along a distal end of the frame. Each distal anchor is provided with a cushion cover. An outer fabric member surrounds the frame and may extend outwardly from the frame in an expanded condition for providing an improved seal in the region of a native annulus. A valve body is positioned within an interior of the expandable from for allowing blood flow in only one direction. In preferred embodiments, the cushions are positioned over enlarged head portions of the distal anchors for further reducing trauma on surrounding tissue.

US Patent:

20210038377, Feb 11, 2021

Filed:

Oct 28, 2020

Appl. No.:

17/083117

Inventors:

- Huntington Beach CA, US
John Paul USSIA - Huntington Beach CA, US
Christine Thanh NGUYEN - Huntington Beach CA, US
Christine Thao NGUYEN - Huntington Beach CA, US

International Classification:

A61F 2/24

Abstract:

Devices for assisting with the functioning of a tricuspid valve of a heart include a shaft, a flow optimizer, and an anchoring mechanism. A tilting mechanism can be configured to tilt the shaft relative to a central axis of the anchoring mechanism. Leaflets (e.g., multi-layer leaflets) of the flow optimizer can include a membrane and a rim, and the rim can have a higher stiffness than the membrane.

US Patent:

20200368016, Nov 26, 2020

Filed:

May 22, 2020

Appl. No.:

16/882226

Inventors:

- Huntington Beach CA, US
John Paul USSIA - Huntington Beach CA, US
Christine Thanh NGUYEN - Huntington Beach CA, US
Christine Thao NGUYEN - Huntington Beach CA, US

International Classification:

A61F 2/24

Abstract:

Devices for assisting with the functioning of a tricuspid valve of a heart include a shaft, a flow optimizer, and an anchoring mechanism. A tilting mechanism can be configured to tilt the shaft relative to a central axis of the anchoring mechanism. Leaflets (e.g., multi-layer leaflets) of the flow optimizer can include a membrane and a rim, and the rim can have a higher stiffness than the membrane.

US Patent:

20190142585, May 16, 2019

Filed:

Jan 14, 2019

Appl. No.:

16/247403

Inventors:

- Irvine CA, US
Luca Pesce - Huntington Beach CA, US
Glen T. Rabito - Lake Forest CA, US
Christine Thanh Nguyen - Santa Ana CA, US

International Classification:

A61F 2/24

Abstract:

A prosthesis for placement within a native mitral valve includes an expandable frame having locking tabs disposed along a proximal end. A plurality of distal anchors are disposed along a distal end of the frame. Each distal anchor is provided with a cushion cover. An outer fabric member surrounds the frame and may extend outwardly from the frame in an expanded condition for providing an improved seal in the region of a mitral annulus. A valve body is positioned within an interior of the expandable from for allowing blood flow in only one direction. In preferred embodiments, the cushions are positioned over enlarged head portions of the distal anchors for further reducing trauma on surrounding tissue.

US Patent:

20180036122, Feb 8, 2018

Filed:

Aug 24, 2017

Appl. No.:

15/685395

Inventors:

- Irvine CA, US
Keith E. Myers - Lake Forest CA, US
Jeffrey P. DuMontelle - Irvine CA, US
Christine Nguyen - Garden Grove CA, US

International Classification:

A61F 2/24
A61L 27/04
A61L 27/26
A61L 27/38
A61L 27/18
A61L 27/50

Abstract:

The present invention provides valve prostheses adapted to be initially crimped in a narrow configuration suitable for catheterization through body ducts to a target location and adapted to be deployed by exerting substantially radial forces from within by means of a deployment device to a deployed state in the target location.