Christine Phuong Nguyen

US Patent:

6682559, Jan 27, 2004

Filed:

Jan 29, 2001

Appl. No.:

09/772526

Inventors:

Keith Myers - Lake Forest CA
Christine Nguyen - Garden Grove CA

Assignee:

3F Therapeutics, Inc. - Lake Forest CA

International Classification:

A61F 206

US Classification:

623 213, 623 212

Abstract:

A tubular prosthetic semilunar or atrioventricular heart valve is formed by cutting flat, flexible leaflets according to a pattern. The valve is constructed by aligning the side edges of adjacent leaflets so that the leaflet inner faces engage each other, and then suturing the leaflets together with successive stitches along a fold line adjacent the side edges. During operation, when the leaflets open and close, the leaflets fold along the fold line. Distal tabs extend beyond the distal end of each leaflet. The tab portions of adjacent leaflets are folded over each other and sewn together to form commissural attachment tabs. The commissural tabs provide commissural attachment points to accommodate sutures and the like in order to secure the tab to a vessel wall, if a semilunar valve, and papillary muscles and/or chordae tendineae, if an atrioventricular valve.

US Patent:

6911043, Jun 28, 2005

Filed:

Jan 5, 2004

Appl. No.:

10/751549

Inventors:

Keith Myers - Lake Forest CA, US
Christine Nguyen - Garden Grove CA, US

Assignee:

3F Therapeutics, Inc. - Lake Forest CA

International Classification:

A61F002/06

US Classification:

623 213, 623 21

Abstract:

A tubular prosthetic semilunar or atrioventricular heart valve is formed by cutting flat, flexible leaflets according to a pattern. The valve is constructed by aligning the side edges of adjacent leaflets so that the leaflet inner faces engage each other, and then suturing the leaflets together with successive stitches along a fold line adjacent the side edges. The stitches are placed successively from a proximal in-flow end of each leaflet toward a distal out-flow end. During operation, when the leaflets open and close, the leaflets fold along the fold line. Distal tabs extend beyond the distal end of each leaflet. The successive stitches terminate proximal of the distal tab portion so that no locked stitches are placed along the distal portion of the fold line. The tab portions of adjacent leaflets are folded over each other and sewn together to form commissural attachment tabs. The commissural tabs provide commissural attachment points to accommodate sutures and the like in order to secure the tab to a vessel wall, if a semilunar valve, and papillary muscles and/or chordae tendineae if an atrioventricular valve.

US Patent:

7037333, May 2, 2006

Filed:

Jan 5, 2004

Appl. No.:

10/751799

Inventors:

Keith Myers - Lake Forest CA, US
Christine Nguyen - Garden Grove CA, US

Assignee:

3F Therapeutics, Inc. - Lake Forest CA

International Classification:

A61F 2/06

US Classification:

623 213, 623 212

Abstract:

A tubular prosthetic semilunar or atrioventricular heart valve is formed by cutting flat, flexible leaflets according to a pattern. The valve is constructed by aligning the side edges of adjacent leaflets so that the leaflet inner faces engage each other, and then suturing the leaflets together with successive stitches along a fold line adjacent the side edges. The stitches are placed successively from a proximal in-flow end of each leaflet toward a distal out-flow end. During operation, when the leaflets open and close, the leaflets fold along the fold line. Distal tabs extend beyond the distal end of each leaflet. The successive stitches terminate proximal of the distal tab portion so that no locked stitches are placed along the distal portion of the fold line. The tab portions of adjacent leaflets are folded over each other and sewn together to form commissural attachment tabs. The commissural tabs provide commissural attachment points to accommodate sutures and the like in order to secure the tab to a vessel wall, if a semilunar valve, and papillary muscles and/or chordae tendineae if an atrioventricular valve.

US Patent:

20040117009, Jun 17, 2004

Filed:

Sep 23, 2003

Appl. No.:

10/668650

Inventors:

Douglas Cali - Mission Viejo CA, US
Keith Myers - Lake Forest CA, US
Brian Biancucci - Mission Viejo CA, US
Jason Artof - Huntington Beach CA, US
Christine Nguyen - Glendora CA, US
Rodolfo Quijano - Laguna Hills CA, US

International Classification:

A61F002/24

US Classification:

623/002120, 623/002130

Abstract:

An improved prosthetic mitral valve is provided having advantageous hemodynamic performance, nonthrombogenicity, and durability. The valve includes a valve body having an inflow annulus and an outflow annulus. Commissural attachment locations are disposed adjacent the outflow annulus. An anterior leaflet and a posterior leaflet of the valve are shaped differently from one another. The inflow annulus preferably is scalloped so as to have a saddle-shaped periphery having a pair of relatively high portions separated by a pair of relatively low portions. The anterior high portion preferably is vertically higher than the posterior high portion.

US Patent:

20060025857, Feb 2, 2006

Filed:

Apr 22, 2005

Appl. No.:

11/112757

Inventors:

Bjarne Bergheim - Laguna Hills CA, US
Keith Meyers - Lake Forest CA, US
Jeff DuMontelle - Irvine CA, US
Christine Nguyen - Garden Grove CA, US

International Classification:

A61F 2/24

US Classification:

623002180

Abstract:

The present invention provides valve prostheses adapted to be initially crimped in a narrow configuration suitable for catheterization through body ducts to a target location and adapted to be deployed by exerting substantially radial forces from within by means of a deployment device to a deployed state in the target location.

US Patent:

20070173932, Jul 26, 2007

Filed:

Dec 7, 2006

Appl. No.:

11/608098

Inventors:

Douglas Cali - Mission Viejo CA, US
Keith Myers - Lake Forest CA, US
Brian Biancucci - Mission Viejo CA, US
Jason Artof - Huntington Beach CA, US
Christine Nguyen - Glendora CA, US
Rodolfo Quijano - Laguna Hills CA, US

Assignee:

3F THERAPEUTICS, INC. - Lake Forest CA

International Classification:

A61F 2/24

US Classification:

623002130, 623901000, 623002120

Abstract:

An improved prosthetic mitral valve is provided having advantageous hemodynamic performance, nonthrombogenicity, and durability. The valve includes a valve body having an inflow annulus and an outflow annulus. Commissural attachment locations are disposed adjacent the outflow annulus. An anterior leaflet and a posterior leaflet of the valve are shaped differently from one another. The inflow annulus preferably is scalloped so as to have a saddle-shaped periphery having a pair of relatively high portions separated by a pair of relatively low portions. The anterior high portion preferably is vertically higher than the posterior high portion.

US Patent:

20070270944, Nov 22, 2007

Filed:

Mar 12, 2007

Appl. No.:

11/685025

Inventors:

Bjarne Bergheim - Laguna Hills CA, US
Keith Myers - Lake Forest CA, US
Jeff DuMontelle - Irvine CA, US
Christine Nguyen - Garden Grove CA, US

Assignee:

3F Therapeutics, Inc. - Lake Forest CA

International Classification:

A61F 2/24

US Classification:

623002180

Abstract:

The present invention provides valve prostheses adapted to be initially crimped in a narrow configuration suitable for catheterization through body ducts to a target location and adapted to be deployed by exerting substantially radial forces from within by means of a deployment device to a deployed state in the target location.

US Patent:

20090018655, Jan 15, 2009

Filed:

Jul 13, 2007

Appl. No.:

11/777733

Inventors:

John Brunelle - Newport Coast CA, US
Joshua Siegel - Exeter NH, US
Christine Nguyen - Glendora CA, US
Brenda Yantzer - Gainesville FL, US
Thomas Sander - Gainesville FL, US

International Classification:

A61F 2/08

US Classification:

623 1319, 623 1311

Abstract:

Disclosed are biocompatible implants that combine a scaffold material for supporting long term repair of a soft tissue with an elongated member such as a suture for aiding in placement of the scaffold during a surgical procedure as well as for immediate mechanical reinforcement of a repair site. The components of an implant are combined such that a longitudinal load placed upon a composite structure can be borne primarily by the elongated member and the scaffold material is isolated from the longitudinal load. Thus, the scaffold material of a composite can be protected from damage due to applied loads and stresses during and following a surgical procedure.