Feng Xu

US Patent:

20080045725, Feb 21, 2008

Filed:

Apr 26, 2007

Appl. No.:

11/740667

Inventors:

Jerry Murry - Newbury Park CA, US
Edward Corley - Freehold NJ, US
Feng Xu - Staten Island NY, US
Bryon Simmons - Princeton NJ, US

International Classification:

C07D 209/00

US Classification:

548515000

Abstract:

The present invention is concerned with novel processes for the preparation of (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane or a pharmaceutically acceptable salt thereof, and (−)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane or a pharmaceutically acceptable salt thereof. These compounds have pharmaceutical utility and are known to be useful for treating e.g., depression, anxiety disorders, eating disorders and urinary incontinence.

US Patent:

20100298574, Nov 25, 2010

Filed:

May 18, 2010

Appl. No.:

12/782705

Inventors:

Jerry A. Murry - Newbury Park CA, US
Edward G. CORELY - Freehold NJ, US
Feng Xu - Staten Island NY, US
Bryon Simmons - Princeton NJ, US

International Classification:

C07D 209/52

US Classification:

548452

Abstract:

The present invention is concerned with novel processes for the preparation of (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane or a pharmaceutically acceptable salt thereof, and (−)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane or a pharmaceutically acceptable salt thereof. These compounds have pharmaceutical utility and are known to be useful for treating e.g., depression, anxiety disorders, eating disorders and urinary incontinence.

US Patent:

20110295020, Dec 1, 2011

Filed:

Aug 10, 2011

Appl. No.:

13/207279

Inventors:

Jerry A. MURRY - Newbury Park CA, US
Edward G. CORLEY - Freehold NJ, US
Feng XU - Staten Island NY, US
Bryon SIMMONS - Princeton NJ, US

International Classification:

C07D 209/52
C07C 211/29
C07C 255/46

US Classification:

548518, 558426, 564442

Abstract:

The present invention is concerned with novel processes for the preparation of (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane or a pharmaceutically acceptable salt thereof, and (−)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane or a pharmaceutically acceptable salt thereof. These compounds have pharmaceutical utility and are known to be useful for treating e.g., depression, anxiety disorders, eating disorders and urinary incontinence.

US Patent:

20180319738, Nov 8, 2018

Filed:

Nov 22, 2017

Appl. No.:

15/820959

Inventors:

Jerry A. MURRY - Newbury Park CA, US
Edward G. CORLEY - Freehold NJ, US
Feng XU - Staten Island NY, US
Bryon SIMMONS - Princeton NJ, US

International Classification:

C07C 255/46
C07C 215/38
C07C 211/29
C07D 209/52
C07C 215/20

Abstract:

The present invention is concerned with novel processes for the preparation of (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane or a pharmaceutically acceptable salt thereof, and (−)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane or a pharmaceutically acceptable salt thereof. These compounds have pharmaceutical utility and are known to be useful for treating e.g., depression, anxiety disorders, eating disorders and urinary incontinence.

US Patent:

20140163240, Jun 12, 2014

Filed:

Jul 18, 2013

Appl. No.:

13/945605

Inventors:

Jerry A. Murry - Newbury Park CA, US
Edwin G. Corley - Freehold NJ, US
Feng Xu - Staten Island NY, US
Bryon Simmons - Princeton NJ, US

International Classification:

C07D 209/52
C07C 215/38
C07C 211/29
C07C 255/46

US Classification:

548515, 558426, 564442

Abstract:

The present invention is concerned with novel processes for the preparation of (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane or a pharmaceutically acceptable salt thereof, and (−)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane or a pharmaceutically acceptable salt thereof. These compounds have pharmaceutical utility and are known to be useful for treating e.g., depression, anxiety disorders, eating disorders and urinary incontinence.