Hui Jiang

US Patent:

20100268085, Oct 21, 2010

Filed:

Nov 13, 2008

Appl. No.:

12/742255

Inventors:

Jochen Kruecker - Washington DC, US
Sheng Xu - Rockville MD, US
Hui Jiang - Issaquah WA, US

Assignee:

KONINKLIJKE PHILIPS ELECTRONICS N.V. - EINDHOVEN

International Classification:

A61B 8/14

US Classification:

600443

Abstract:

A method for interventional navigation using 3D contrast-enhanced ultrasound (CEUS) imaging () includes acquiring a reference 3D CEUS volume and tracking information for a desired portion of an anatomy () subject to an interventional procedure with an instrument (), during a useful lifetime of a contrast enhancement agent administered to the anatomy. Real-time tracked tissue images () are acquired during the interventional procedure. In addition, a corresponding CEUS multiplanar reconstruction (MPR) () for at least one of the acquired real-time tracked tissue images is generated. At least one of the acquired real-time tracked tissue images is displayed () along with the corresponding CEUS MPR. The displayed real-time tracked tissue image includes at least an image of the instrument within the desired portion of the anatomy and the CEUS MPR corresponds to the displayed real-time tracked tissue image. The CEUS MPR image includes a contrast enhanced MPR image obtained from the reference 3D CEUS volume and includes a target volume of interest (), thereby providing a concurrent display of contrast enhanced image information and tissue image information useful for the interventional navigation at least subsequent to the expiration of the contrast enhancement useful lifetime.

US Patent:

20120238842, Sep 20, 2012

Filed:

Mar 15, 2012

Appl. No.:

13/421013

Inventors:

Hui Jiang - Clarksburg MD, US

Assignee:

SENSORS FOR MEDICINE AND SCIENCE, INC. - Germantown MD

International Classification:

A61B 5/00
A61B 6/00
A61B 5/1459
A61B 5/145

US Classification:

600316, 600300, 600365, 600476, 600309, 600310

Abstract:

An implantable device with in vivo functionality, where the functionality of the device is negatively affected by ROS typically associated with inflammation reaction as well as chronic foreign body response as a result of tissue injury, is at least partially surrounded by a protective material, structure, and/or a coating that prevents damage to the device from any inflammation reactions. The protective material, structure, and/or coating is a biocompatible metal, preferably silver, platinum, palladium, gold, manganese, or alloys or oxides thereof that decomposes reactive oxygen species (ROS), such as hydrogen peroxide, and prevents ROS from oxidizing molecules on the surface of or within the device. The protective material, structure, and/or coating thereby prevents ROS from degrading the in vivo functionality of the implantable device.

US Patent:

20180146885, May 31, 2018

Filed:

Jun 15, 2017

Appl. No.:

15/623474

Inventors:

- Germantown MD, US
Hui Jiang - Clarksburg MD, US

Assignee:

Senseonics, Incorporated - Germantown MD

International Classification:

A61B 5/07
A61B 5/145
A61B 5/1459

Abstract:

An implantable device with in vivo functionality, where the functionality of the device is negatively affected by ROS typically associated with inflammation reaction as well as chronic foreign body response as a result of tissue injury, is at least partially surrounded by a protective material, structure, and/or a coating that prevents damage to the device from any inflammation reactions. The protective material, structure, and/or coating is a biocompatible metal, preferably silver, platinum, palladium, gold, manganese, or alloys or oxides thereof that decomposes reactive oxygen species (ROS), such as hydrogen peroxide, and prevents ROS from oxidizing molecules on the surface of or within the device. The protective material, structure, and/or coating thereby prevents ROS from degrading the in vivo functionality of the implantable device.

US Patent:

20170202517, Jul 20, 2017

Filed:

Feb 3, 2017

Appl. No.:

15/424540

Inventors:

- Germantown MD, US
Hui JIANG - Clarksburg MD, US

Assignee:

Senseonics, Incorporated - Germantown MD

International Classification:

A61B 5/00
A61B 5/1459
A61N 1/375
A61B 5/145

Abstract:

An implantable device with in vivo functionality, where the functionality of the device is negatively affected by ROS typically associated with inflammation reaction as well as chronic foreign body response as a result of tissue injury, is at least partially surrounded by a protective material, structure, and/or a coating that prevents damage to the device from any inflammation reactions. The protective material, structure, and/or coating is a biocompatible metal, preferably silver, platinum, palladium, gold, manganese, or alloys or oxides thereof that decomposes reactive oxygen species (ROS), such as hydrogen peroxide, and prevents ROS from oxidizing molecules on the surface of or within the device. The protective material, structure, and/or coating thereby prevents ROS from degrading the in vivo functionality of the implantable device.

US Patent:

20140088383, Mar 27, 2014

Filed:

Sep 11, 2013

Appl. No.:

14/023837

Inventors:

- Germantown MD, US
Hui Jiang - Clarksburg MD, US

Assignee:

Senseonics, Incorporated - Germantown MD

International Classification:

A61B 5/00
A61B 5/1455
A61B 5/145

US Classification:

600310, 600309, 600365

Abstract:

An implantable device with in vivo functionality, where the functionality of the device is negatively affected by ROS typically associated with inflammation reaction as well as chronic foreign body response as a result of tissue injury, is at least partially surrounded by a protective material, structure, and/or a coating that prevents damage to the device from any inflammation reactions. The protective material, structure, and/or coating is a biocompatible metal, preferably silver, platinum, palladium, gold, manganese, or alloys or oxides thereof that decomposes reactive oxygen species (ROS), such as hydrogen peroxide, and prevents ROS from oxidizing molecules on the surface of or within the device. The protective material, structure, and/or coating thereby prevents ROS from degrading the in vivo functionality of the implantable device.