James Robert Trout

US Patent:

6521229, Feb 18, 2003

Filed:

Jun 26, 2001

Appl. No.:

09/888655

Inventors:

Mark C. Jenkins - Davidsonville MD
Ronald Fayer - Columbia MD
James Trout - Columbia MD

Assignee:

The United States of America as represented by the Secretary of Agriculture - Washington DC

International Classification:

A61K 39395

US Classification:

4241511, 4241991, 4242691, 435 722, 435342, 5303881, 5303886, 5303891

Abstract:

Recombinant proteins have been developed for the immunization of animals against cryptosporidiosis. The proteins are effective for the immunization of a variety of animals against , particularly for the production of hyperimmune colostrum that may be used to confer passive immunity against the parasite. Isolated DNA sequences which encode these proteins have also been developed. The DNA sequences may be inserted into recombinant DNA molecules such as cloning vectors or expression vectors for the transformation of cells and the production of the proteins.

US Patent:

6710166, Mar 23, 2004

Filed:

Jun 26, 2001

Appl. No.:

09/888501

Inventors:

Mark C. Jenkins - Davidsonville MD
Ron Fayer - Columbia MD
James Trout - Columbia MD

Assignee:

The United States of America as represented by the Secretary of Agriculture - Washington DC

International Classification:

A61K 3800

US Classification:

530300, 4241511, 4241911, 4242691, 435 722, 435342

Abstract:

Recombinant proteins have been developed for the immunization of animals against cryptosporidiosis. The proteins are effective for the immunization of a variety of animals against , particularly for the production of hyperimmune colostrum that may be used to confer passive immunity against the parasite. Isolated DNA sequences which encode these proteins have also been developed. The DNA sequences may be inserted into recombinant DNA molecules such as cloning vectors or expression vectors for the transformation of cells and the production of the proteins.

US Patent:

62779737, Aug 21, 2001

Filed:

Nov 30, 1999

Appl. No.:

9/451117

Inventors:

Mark C. Jenkins - Davidsonville MD
Ron Fayer - Columbia MD
James Trout - Columbia MD

Assignee:

The United States of America as represented by the Secretary of Agriculture - Washington DC

International Classification:

C07H 2102

US Classification:

536 231

Abstract:

Recombinant proteins have been developed for the immunization of animals against cryptosporidiosis. The proteins are effective for the immunization of a variety of animals against Cryptosporidium parvum, particularly for the production of hyperimmune colostrum that may be used to confer passive immunity against the parasite. Isolated DNA sequences which encode these proteins have also been developed. The DNA sequences may be inserted into recombinant DNA molecules such as cloning vectors or expression vectors for the transformation of cells and the production of the proteins.