Awards:
Healthgrades Honor Roll
Alpha Omega Alpha Medical Student Honor Society, 1981
Merck Senior Fellow Award, 1995
First Place Knoll Thyroid Research Award, 1995
Fellow, American College of Endocrinology, 1995
NIH Physician Scientist Award, 1992
AMA Physician Recognition Award with Commendation, 2012
International Society for Clinical Densitometry Certified Clinical Densitometrist, 2009
Endocrinology, Third Edition, edited by Leslie J. deGroot
Principles of Hormone Action, Second Messenger Signaling Pathways: Phosphatidylinositol and Calcium, 1995
Laakkonen LJ, Guarnieri F, Perlman JH, Gershengorn MC, Osman R: A refined model of the thyrotrophin-releasing hormone (TRH) receptor binding pocket. Novel mixed mode Monte Carlo/stochastic dynamics simulations of the complex between TRH and TRH receptor. Biochemistry 1996 Jun 18; 35(24):7651-63
Perlman JH, Colson AO, Jain R, Czyzewski B, Cohen LA, Osman R, Gershengorn MC: Role of the extracellular loops of the thyrotrophin-releasing hormone receptor: evidence for an initial interaction with thyrotrophin-releasing hormone. Biochemistry 1997 Dec 16; 36(50):15670-6
Perlman JH, Gershengorn MC: Thyrotrophin-releasing hormone stimulation of phosphoinositide hydrolysis desensitizes. Evidence against mediation by protein kinase C or calcium. Endocrinology 1991 Nov; 129(5):2679-86
Perlman JH, Thaw CN, Laakkonen L, Bowers CY, Osman R, Gershengorn MC:
Hydrogen bonding interactions of thyrotrophin-releasing hormone (TRH) with transmembrane tyrosine 106 of the TRH receptor. J Biol Chem 1994; 269(3):1610-3
Perlman JH, Colson AO, Wang W, Bence K, Osman R, Gershengorn MC: Interactions between conserved residues in transmembrane helices 1, 2, and 7 of the thyrotrophin-releasing hormone receptor. J Biol Chem 1997 May; 272(18):11937-42
Chu W, Perlman JH, Gershengorn MC, Moeller KD: Thyrotrophin-releasing hormone analogs: a building block approach to the construction of tetracyclic peptidomimetics. Bioorg Med Chem Lett 1998 Nov 3; 8(21):3093-6
Rutledge LD, Perlman JH, Gershengorn MC, Marshall GR, Moeller KD: Conformationally restricted TRH analogs: a probe for the pyroglutamate region. J Med Chem 1996 Apr 12; 39(8):1571-4
Perlman JH, Laakkonen L, Osman R, Gershengorn MC: A model of the thyrotrophin-releasing hormone (TRH) receptor binding pocket. Evidence for a second direct interaction between transmembrane helix 3 and TRH. J Biol Chem 1994 Sep 23; 269(38):23383-6.
Colson AO, Perlman JH, Smolyar A, Gershengorn MC, Osman R: Static and dynamic roles of extracellular loops in G protein-coupled receptors: a mechanism for sequential binding of thyrotrophin-releasing hormone to its receptor. Biophys J 1998 Mar; 74(3):1087-1100
Colson AO, Perlman JH, Jinsi-Parimoo A, Nussenzveig DR, Osman R, Gershengorn MC: A hydrophobic cluster between transmembrane helices 5 and 6 constrains the thyrotrophin-releasing hormone receptor in an inactive conformation. Mol Pharmacol 1998 Dec; 54(6):968-78
Laakkonen L, Li W, Perlman JH, Guarnieri F, Osman R, Moeller KD, Gershengorn MC: Restricted analogs provide evidence of a biologically active conformation of thyrotrophin-releasing hormone. Mol Pharmacol 1996 Jun; 49(6):1092-6
Perlman JH, Laakkonen LJ, Guarnieri F, Osman R, Gershengorn MC: A refined model of the thyrotrophin-releasing hormone (TRH) receptor binding pocket. Experimental analysis and energy minimization of the complex between TRH and TRH receptor. Biochemistry 1996 Jun 18; 35(24):7643-50
Perlman JH, Nussenzveig DR, Osman R, Gershengorn MC: Thyrotrophin-releasing hormone binding to the mouse pituitary receptor does not involve ionic interactions. A model for neutral peptide binding to G protein-coupled receptors. J Biol Chem 1992 Dec 5; 267(34):24413-7
Perlman JH, Laakkonen L, Thaw CN, Osman R, Gershengorn MC: Analysis of the role of transmembrane helix three of the thyrotrophin-releasing hormone (TRH) receptor in directly binding TRH. Trans Assoc Am Physicians 1993; 106:162-7.
Perlman JH, Laakkonen L, Osman R, Gershengorn MC: Distinct roles for arginines in transmembrane helices 6 and 7 of the thyrotrophin-releasing hormone receptor. Mol Pharmacol 1995 Mar; 47(3):480-4
Jain R, Singh J, Perlman JH, Gershengorn MC: Synthesis and biology of new TRH analogues. Bioorg Med Chem 2002 Jan; 10(1):189-94
Perlman JH, Wang W, Nussenzveig DR, Gershengorn MC: A disulfide bond between conserved extracellular cysteines in the thyrotrophin-releasing hormone receptor is critical for binding. J Biol Chem 1995 Oct 20; 270(42):24682-5
Bucci E, Fronticelli C, Flanigan K, Perlman J, Steiner RF: Fluorescence anisotropy decay studies upon hemoglobin A and its subunits. Biopolymers 1979 May; 18(5):1261-76.