Jin L Xu

US Patent:

7182937, Feb 27, 2007

Filed:

Oct 10, 2001

Appl. No.:

10/398978

Inventors:

Jin Xu - Livingston NJ, US
Stephen W. Mruphy - Rockaway NJ, US
Bala Nayar - Dayton NJ, US
Michael E. Trama - River Vale NJ, US

Assignee:

Block Drug Company, Inc. - Jersey City NJ

International Classification:

A61K 8/00
A61K 8/18
A61Q 11/00

US Classification:

424 49, 424 48, 424 54, 424440, 424667, 424678, 424682, 424719, 4332171, 4332281

Abstract:

A composition for reducing dentinal hypersensitivity and remineralizing exposed dentinal surface and open dentinal tubules, comprising a non-aqueous carrier and a desensitizing amount of a desensitizing/remineralizing agent which consists essentially of a water soluble calcium salt and an incompatible ingredient which would otherwise react with the calcium salt. Upon contact with saliva when applied to an oral cavity, the desensitizing/remineralizing is then formed in situ by the reaction between the calcium salt and the incompatible ingredient, thereby remineralizing exposed dentinal surface and open dentinal tubules.

US Patent:

20020031481, Mar 14, 2002

Filed:

Apr 19, 2001

Appl. No.:

09/838021

Inventors:

Jin Xu - Livingston NJ, US
Bala Nayar - Dayton NJ, US
Marissa Healy - Denville NJ, US

International Classification:

A61K007/16

US Classification:

424/049000

Abstract:

A dentifrice gel or paste comprising from about 40% to 70% by weight baking soda, from about 0.5% to 5% by weight of a blend of natural ingredients, from about 0.5% to 5% by weight of a flavoring oil and a sufficient amount of a stabilizing combination of a xanthan gum binder, at least one betaine surfactant and a humectant comprising glycerin or glycerin and sorbitol in an amount sufficient to render the dentifrice formulation stable to degradation and resistant to syneresis and phase separation.