John M Tsai

US Patent:

6521088, Feb 18, 2003

Filed:

Oct 27, 2000

Appl. No.:

09/698456

Inventors:

Paul H. Richardson - Plainsboro NJ
Ralph M. Trksak - Manville NJ
John J. Tsai - Belle Mead NJ
Eric M. Weisser - Somerset NJ

Assignee:

National Starch and Chemical Investment Holding Corporation - New Castle DE

International Classification:

D21H 1912

US Classification:

162175, 162177, 162178, 1062071, 1062151, 427395

Abstract:

This invention is directed to degraded, hydrated particulate starches that are hydrophobically modified and a method of providing paper with reduced porosity, resistance to liquid penetration and increased surface strength comprising applying to the surface of a paper substrate an effective amount of a surface sizing composition which comprises such starch. In particular, the starches are those in which the starch base is degraded to a water fluidity (WF) of from about 10 to 80 or the modified and/or particulate starch is degraded using a substantially equivalent amount of degradation agent and substantially the same reaction conditions, the starch is modified with a hydrophobic hydrocarbon group of 5 to 23 carbon atoms at about 1 to 20% substitution level by weight of bound hydrophobe based on the weight of starch, and the hydrated starch has a volume average hydrated particle size of at least about 20 microns and a volume fraction of hydrated particles at 1% solids of at least about 5%.

US Patent:

6824792, Nov 30, 2004

Filed:

Jul 17, 2001

Appl. No.:

09/907413

Inventors:

Paul B. Foreman - Somerville NJ
Paul Richardson - Plainsboro NJ
John Tsai - Belle Mead NJ
Jean Paul Remon - Melle, BE
Jody Voorspoels - Reningelst, BE
Dieter Ameye - Waregem, BE
Catherine Callens - Ploegsteert, BE

Assignee:

Universiteit Gent - Ghent
National Starch and Chemical Investment Holding Corporation - New Castle DE

International Classification:

A61K 914

US Classification:

424487, 424484, 424486, 424488, 514772, 5147721, 5147723, 5147724, 5147726, 514777, 514778, 514779

Abstract:

This invention relates to a method of producing a bioadhesive composition comprising the steps of preparing a solution of a solvent and a polymer mixture wherein the polymer mixture comprises at least one natural or synthetic polycarboxylated polymer and at least one polysaccharide; drying the solution to form a solid; and heat treating the solid to effect cross-linking and to form the bioadhesive composition.

US Patent:

6843888, Jan 18, 2005

Filed:

Mar 13, 2001

Appl. No.:

09/804791

Inventors:

Michele M. Merrette - Bridgewater NJ, US
John J. Tsai - Belle Mead NJ, US
Paul H. Richardson - Plainsboro NJ, US

Assignee:

National Starch and Chemical Investment Holding Corporation - New Castle DE

International Classification:

D21H 1724

US Classification:

162175, 1062061, 536102, 536106

Abstract:

This invention relates to a degraded, inhibited cationic starch for use in papermaking systems, which affords improved physical properties, particularly strength. Additionally these derivatives provide easy-to-prepare alternatives totraditional starches, and can even be added directly to the papermaking process without cooking. While the benefits of these starch compositions can be applied to any type of papermaking method, they are especially useful in high shear, high conductivity and recycle systems.

US Patent:

20030099691, May 29, 2003

Filed:

Nov 16, 2001

Appl. No.:

09/991385

Inventors:

Susan Lydzinski - Belle Mead NJ, US
Todd Manegold - Somerset NJ, US
Daniel Solarek - Hillsborough NJ, US
John Tsai - Belle Mead NJ, US
Christine Puglisi - Mountainside NJ, US

International Classification:

A61K009/70
A61K007/16
A61K031/718

US Classification:

424/443000, 514/060000

Abstract:

The present invention relates to a film, particularly an oral film, which contains starch as the main component. Such film is useful for delivering a variety of agents to humans and other animals to produce a therapeutic, organoleptic, or cosmetic effect, including breath fresheners, flavors, fragrances and pharmaceuticals.

US Patent:

20030099692, May 29, 2003

Filed:

Mar 19, 2002

Appl. No.:

10/100260

Inventors:

Susan Lydzinski - Belle Mead NJ, US
Todd Manegold - Somerset NJ, US
Daniel Solarek - Hillsborough NJ, US
John Tsai - Belle Mead NJ, US
Christine Puglisi - Mountainside NJ, US

International Classification:

A61K007/16
A61K009/70
A61K031/718

US Classification:

424/443000, 514/060000

Abstract:

The present invention relates to a film, particularly an oral film, which contains starch as the main component. Such film is useful for delivering a variety of agents to humans and other animals to produce a therapeutic, organoleptic, pharmacological, agricultural or cosmetic effect, including breath fresheners, flavors, fragrances and pharmaceuticals.

US Patent:

47418044, May 3, 1988

Filed:

Apr 3, 1987

Appl. No.:

7/034133

Inventors:

Daniel B. Solarek - Somerville NJ
Patrick G. Jobe - Westfield NJ
Martin M. Tessler - Edison NJ
Robert L. Billmers - Stockton NJ
Diane J. Lamb - Bound Brook NJ
John J. Tsai - Belle Mead NJ

Assignee:

National Starch and Chemical Corporation - Bridgewater NJ

International Classification:

D21H 320

US Classification:

162175

Abstract:

Polysaccharide aldehydes having the formula ##STR1## starch, cellulose, and gum aldehydes, are useful for imparting wet, dry, or temporary wet strength to paper. They are prepared by a non-oxidative method which involves reacting the polysaccharide base, in the presence of alkali, with a derivatizing acetal reagent having the general structure ##STR2## and then hydrolyzing the acetal by adjusting the pH to less than 7, preferably 2-4. In the formula, n is 1-3; R. sup. 11 and R. sup. 12 are independently an alkyl, aryl, aralkyl, or alkaryl group when n is 1, R. sup. 11 or R. sup. 12 is one of the groups when n is 2, or R. sup. 11 and R. sup. 12 are not present when n is 3; R. sup. 13 is an alkyl group, optionally containing an ether linkage, or an aryl, aralkyl, or alkaryl group; R. sup. 14 and R. sup. 15 are individually a hydrogen or a methyl group; R. sup. 16, R. sup. 17, and R. sup.

US Patent:

48047694, Feb 14, 1989

Filed:

Apr 10, 1987

Appl. No.:

7/037282

Inventors:

Daniel B. Solarek - Somerville NJ
Patrick G. Jobe - Westfield NJ
Martin M. Tessler - Edison NJ
Robert L. Billmers - Stockton NJ
Diane J. Lamb - Bound Brook NJ
John J. Tsai - Belle Mead NJ

Assignee:

National Starch and Chemical Corporation - Bridgewater NJ

International Classification:

C07D31906

US Classification:

549374

Abstract:

Polysaccharide aldehydes having the formula Sacch-O-CH. sub. 2 -CH. dbd. CH-CHO, Sacch-O-CH. sub. 2 -C. tbd. C-CHO, ##STR1## such as starch, cellulose, and gum aldehydes, are useful for imparting wet, dry, or temporary wet strength to paper. They are prepared by a non-oxidative method which involves reacting the polysaccharide base, in the presence of alkali, with a derivatizing acetal reagent having the general structure ##STR2## and then hydrolyzing the acetal by adjusting the pH to less than 7, preferably 2-4. In the formulas, n is 1-3; R. sup. 11 and R. sup. 12 are independently an alkyl, aryl, aralkyl, or alkaryl group when n is 1, R. sup. 11 or R. sup. 12 is one of the groups when n is 2, or R. sup. 11 and R. sup. 12 are not present when n is 3; R. sup. 13 is an alkyl group, optionally containing an ether linkage, or an aralkyl group; R. sup. 14 and R. sup.

US Patent:

62842358, Sep 4, 2001

Filed:

Feb 11, 2000

Appl. No.:

9/502585

Inventors:

Paul B. Foreman - Somerville NJ
Paul Richardson - Plainsboro NJ
John Tsai - Belle Mead NJ
Jean Paul Remon - Melle, BE
Jody Voorspoels - Reningelst, BE
Dieter Ameye - Waregem, BE
Catherine Callens - Ploegsteert, BE

Assignee:

National Starch and Chemical Company Investment Holding Corporation - Wilmington DE

International Classification:

A61K 3174

US Classification:

424 7808

Abstract:

This invention relates to a method of producing a bioadhesive composition comprising the steps of preparing a solution of a solvent and a polymer mixture wherein the polymer mixture comprises at least one natural or synthetic polycarboxylated polymer and at least one polysaccharide; drying the solution to form a solid; and heat treating the solid to effect cross-linking and to form the bioadhesive composition.