Joseph L Giuffrida

US Patent:

8583238, Nov 12, 2013

Filed:

Oct 2, 2012

Appl. No.:

13/633358

Inventors:

Joseph P. Giuffrida - Hinckley OH, US

Assignee:

Great Lakes Neuro Technologies Inc. - Cleveland OH

International Classification:

A61N 1/04

US Classification:

607 45

Abstract:

The present invention relates to a system and methods for noninvasively providing therapy for movement disorder symptoms. The present invention provides such a therapy system which provides trans-cranial direct current stimulation (tDCS) in order to treat those symptoms and the disorders. The present invention further provides such tDCS therapy while the subject sleeps in order to minimize the time required and impact of the therapy on the subject's waking life. The system, methods, and devices of the present invention are intended to provide a low-dose electrical current, trans-cranially, to a specific area of the subject's brain while he or she sleeps in order to decrease the occurrence, severity, and duration of the symptoms of movement disorders. The present invention aims to reduce the amount of medication necessary, counteract the effects of medication wearing off during sleep, and to overall improve the quality of life of subjects suffering from movement disorders.

US Patent:

20130123684, May 16, 2013

Filed:

Jun 3, 2011

Appl. No.:

13/153063

Inventors:

Joseph P. Giuffrida - Hinckley OH, US
Dustin A. Heldman - Shaker Heights OH, US
Thomas O. Mera - South Euclid OH, US

Assignee:

GREAT LAKES NEUROTECHNOLOGIES INC. - Cleveland OH

International Classification:

A61N 1/36
A61M 5/168

US Classification:

604 65, 607 45

Abstract:

A system and method for tuning the parameters of a therapeutic medical device comprises a movement measurement data acquisition system capable of wireless transmission; processing comprising kinematic feature extraction, a scoring algorithm trained using scores from expert clinicians, a therapeutic device parameter setting adjustment suggestion algorithm preferably trained using the parameter setting adjustment judgments of expert clinicians; and a display and/or means of updating the parameter settings of the treatment device. The invention facilitates the treatment of movement disorders including Parkinson's disease, essential tremor and the like by optimizing deep brain stimulation (DBS) parameter settings, eliminating as much as possible motor symptoms and reducing time and costs of surgical and outpatient procedures and improving patient outcomes. In preferred embodiments, the system provides recommendations for treatment which may be semi-automatically or automatically applied to update the parameter settings of a treatment device such as a DBS implant.

US Patent:

20140074179, Mar 13, 2014

Filed:

Jun 15, 2013

Appl. No.:

13/918948

Inventors:

Dustin A Heldman - Shaker Heights OH, US
Christopher L Pulliam - Shaker Heights OH, US
Joseph P Giuffrida - Hinckley OH, US
Thomas O Mera - South Euclid OH, US

International Classification:

A61N 1/372

US Classification:

607 45

Abstract:

The present invention relates to methods for tuning treatment parameters in movement disorder therapy systems. The present invention further relates to a system for screening patients to determine viability as candidates for certain therapy modalities, such as deep brain stimulation (DBS). The present invention still further provides methods of quantifying movement disorders for the treatment of patients who exhibit symptoms of such movement disorders including, but not limited to, Parkinson's disease and Parkinsonism, Dystonia, Chorea, and Huntington's disease, Ataxia, Tremor and Essential Tremor, Tourette syndrome, stroke, and the like. The present invention yet further relates to methods of tuning a therapy device using objective quantified movement disorder symptom data acquired by a movement disorder diagnostic device to determine the therapy setting or parameters to be provided to the subject via his or her therapy device. The present invention also provides treatment and tuning remotely, allowing for home monitoring of subjects.

US Patent:

20140074180, Mar 13, 2014

Filed:

Sep 10, 2013

Appl. No.:

14/022376

Inventors:

Dustin A. Heldman - Shaker Heights OH, US
Christopher L. Pulliam - Shaker Heights OH, US
Joseph P. Giuffrida - Hinckley OH, US
Thomas O. Mera - South Euclid OH, US

International Classification:

A61N 1/372
A61N 1/36

US Classification:

607 45

Abstract:

The present invention relates to methods for remotely and intelligently tuning movement disorder of therapy systems. The present invention still further provides methods of quantifying movement disorders for the treatment of patients who exhibit symptoms of such movement disorders including, but not limited to, Parkinson's disease and Parkinsonism, Dystonia, Chorea, and Huntington's disease, Ataxia, Tremor and Essential Tremor, Tourette syndrome, stroke, and the like. The present invention yet further relates to methods of remotely and intelligently or automatically tuning a therapy device using objective quantified movement disorder symptom data to determine the therapy setting or parameters to be transmitted and provided to the subject via his or her therapy device. The present invention also provides treatment and tuning intelligently, automatically and remotely, allowing for home monitoring of subjects.

US Patent:

8187209, May 29, 2012

Filed:

Mar 17, 2005

Appl. No.:

11/082668

Inventors:

Joseph Giuffrida - North Royalton OH, US

Assignee:

Great Lakes Neurotechnologies Inc - Valley View OH

International Classification:

A61B 5/103

US Classification:

600595

Abstract:

The present invention relates to a movement disorder monitor, and a method of measuring the severity of a subject's movement disorder. The present invention additionally relates to a drug delivery system for dosing a subject in response to the increased severity of a subject's symptoms. The present invention provides for a system and method, which can accurately quantify symptoms of movements disorders, accurately quantifies symptoms utilizing both kinetic information and electromyography (EMG) data, that can be worn continuously to provide continuous information to be analyzed as needed by the clinician, that can provide analysis in real-time, that allows for home monitoring of symptoms in subject's with these movement disorders to capture the complex fluctuation patterns of the disease over the course of days, weeks or months, that maximizes subject safety, and that provides remote access to the clinician or physician.

US Patent:

20210085976, Mar 25, 2021

Filed:

Oct 13, 2020

Appl. No.:

17/068973

Inventors:

- Cleveland OH, US
Christopher L. Pulliam - Shaker Heights OH, US
Joseph P. Giuffrida - Hinckley OH, US
Thomas O. Mera - Columbus OH, US

Assignee:

Great Lakes NeuroTechnologies Inc. - Cleveland OH

International Classification:

A61N 1/36
A61N 1/372
A61B 5/11
A61B 5/00
A61N 1/05
G16H 20/40
G16H 40/60

Abstract:

The present invention relates to methods for remotely and intelligently tuning movement disorder of therapy systems. The present invention still further provides methods of quantifying movement disorders for the treatment of patients who exhibit symptoms of such movement disorders including, but not limited to, Parkinson's disease and Parkinsonism, Dystonia, Chorea, and Huntington's disease, Ataxia, Tremor and Essential Tremor, Tourette syndrome, stroke, and the like. The present invention yet further relates to methods of remotely and intelligently or automatically tuning a therapy device using objective quantified movement disorder symptom data to determine the therapy setting or parameters to be transmitted and provided to the subject via his or her therapy device. The present invention also provides treatment and tuning intelligently, automatically and remotely, allowing for home monitoring of subjects.

US Patent:

20180361153, Dec 20, 2018

Filed:

Aug 22, 2018

Appl. No.:

16/108772

Inventors:

Dustin A. Heldman - Shaker Heights OH, US
Christopher L. Pulliam - Shaker Heights OH, US
Joseph P. Giuffrida - Hinckley OH, US
Thomas O. Mera - Columbus OH, US

Assignee:

Great Lakes NeuroTechnologies Inc. - Cleveland OH

International Classification:

A61N 1/36
A61B 5/00
A61N 1/372
A61N 1/05
A61B 5/11

Abstract:

The present invention relates to methods for remotely and intelligently tuning movement disorder of therapy systems. The present invention still further provides methods of quantifying movement disorders for the treatment of patients who exhibit symptoms of such movement disorders including, but not limited to, Parkinson's disease and Parkinsonism, Dystonia, Chorea, and Huntington's disease, Ataxia, Tremor and Essential Tremor, Tourette syndrome, stroke, and the like. The present invention yet further relates to methods of remotely and intelligently or automatically tuning a therapy device using objective quantified movement disorder symptom data to determine the therapy setting or parameters to be transmitted and provided to the subject via his or her therapy device. The present invention also provides treatment and tuning intelligently, automatically and remotely, allowing for home monitoring of subjects.