Qs Pharma Feb 1, 2002 - Aug 1, 2010
Founder and President
Sanja Pharmaceuticals Company Feb 1, 2002 - Aug 1, 2010
Cofounder and Ceo, Sanja Pharmaceuticals
Dupont Pharmaceuticals Dec 1, 1996 - Dec 1, 2001
Vice President, Pharmacy R and D
Solvay Pharmaceuticals Sep 1, 1994 - Dec 1, 1996
Director, Product Development
American Cyanamid Mar 1, 1984 - Aug 1, 1994
Scientist and Group Leader and Department Head and Section Manager
Skills:
Product Development Life Sciences Technology Transfer Pharmaceutical Industry R&D Fda Validation Gmp Commercialization Regulatory Affairs
Name / Title
Company / Classification
Phones & Addresses
Madurai Ganesan President
Q S Pharma Llc Pharmacies & Drug Stores
3 Chelsea Pkwy #305, Boothwyn, PA 19061 305 Chelsea Pkwy, Boothwyn, PA 19061 (610)4854270, (610)4855933
Madurai Gurusamy Ganesan - Newark DE, US Ramaswamy Balakrishnan - Chadds Ford PA, US Nutan Kumar Gangrade - Hockessin DE, US Steven D. Roth - Great Neck NY, US
Assignee:
Emet Pharmaceuticals, LLC - Great Neck NY
International Classification:
A61K 9/22 A61K 9/28 A61K 9/32
US Classification:
424468, 424474, 424482
Abstract:
The present invention is directed to a delayed release pharmaceutical composition in solid dosage form comprising a core comprised of a therapeutically effective amount of drug, e. g. , mesalamine, and a pH sensitive coating comprising a mixture of two different pH sensitive polymers, the first pH sensitive polymer dissolves in an aqueous solution at a pH of about 7 or greater and the second pH sensitive polymer dissolves in an aqueous solution at a pH of about 6 or greater, wherein the weight ratio of the first pH sensitive polymer to the second pH sensitive polymer ranges from about 2:1 to about 4:1 and the percent weight gain resulting from the addition of the pH sensitive coating ranges from about 8% up to and including 15% by weight of the core, including any subcoating.
Intimate Coating Of Ibuprofen With Poloxamers To Enhance Aqueous Dissolution
Larry Berger - Chadds Ford PA, US Madurai Ganesan - Newark DE, US Nutan Gangrade - Hockessin DE, US Henricus Gommeren - Hockessin DE, US Torrence Trout - West Chester PA, US
International Classification:
A61K 9/20 A61K 9/36
US Classification:
424464000, 424480000
Abstract:
This invention provides methods for enhancing the dissolution rate of Ibuprofen. More particularly, the invention provides a process for enhancing the solubility of Ibuprofen by intimately coating Ibuprofen particles with a Poloxamer. The invention also provides for a composition comprising a solid dosage form of Ibuprofen, wherein the surfaces of Ibuprofen particles have been intimately coated with a Poloxamer; a composition comprising a fast onset, solid dosage form of Ibuprofen; and a composition comprising Ibuprofen particles intimately coated with a Poloxamer.
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