Nicholas David Cosford - San Diego CA, US Terence Hamill - Lansdale PA, US Theodore Kamenecka - San Diego CA, US Thomas Seiders - San Diego CA, US Jeffrey Roppe - Temecula CA, US Celine Bonnefous - San Diego CA, US Donald Burns - Harleysville PA, US Matthew Braun - Scotch Plains NJ, US Dennis Dean - Cranford NJ, US Joseph Simeone - Harrington Park NJ, US
The present invention is directed to isotopically labeled alkyne derivative compounds, particularly C, C, C, F, O, N, S, H, and H labeled compounds. In particular, the present invention is directed to C, C, C, F, O, N, S, H, and H labeled heterocyclic alkynes and methods of their preparation. The present invention further includes a method of use of the C, F, O, or N labeled heterocyclic alkyne compounds as tracers in positron emission tomography (PET) imaging, particularly in the study of metabolic conditions in mammals, specifically conditions modulated by metabotropic glutamate receptors subtype 5 (mGluR5).
Our world has not benefited from treating children like a disease that needs to be cured. We would need to stop obsessing over everything going perfectly, trying to plan everything, and treating people like profit and loss centers, Matthew Braun, 39, Virginia.