Peng Zhou

US Patent:

7832429, Nov 16, 2010

Filed:

Oct 3, 2005

Appl. No.:

11/242694

Inventors:

Lincoln Young - Ithaca NY, US
Peng Zhou - Newtown PA, US

Assignee:

Rheonix, Inc. - Ithaca NY

International Classification:

F15C 3/00

US Classification:

137829, 417383, 417395

Abstract:

Plastic microfluidic structures having a substantially rigid diaphragm that actuates between a relaxed state wherein the diaphragm sits against the surface of a substrate and an actuated state wherein the diaphragm is moved away from the substrate. As will be seen from the following description, the microfluidic structures formed with this diaphragm provide easy to manufacture and robust systems, as well readily made components such as valves and pumps.

US Patent:

8512502, Aug 20, 2013

Filed:

Jul 23, 2012

Appl. No.:

13/555506

Inventors:

Lincoln C. Young - Ithaca NY, US
Peng Zhou - Newtown PA, US

Assignee:

Rheonix, Inc. - Ithaca NY

International Classification:

B32B 38/04

US Classification:

1562722, 1562728, 1562733, 156285, 1562737, 422502, 422503

Abstract:

Plastic microfluidic structures having a substantially rigid diaphragm that actuates between a relaxed state wherein the diaphragm sits against the surface of a substrate and an actuated state wherein the diaphragm is moved away from the substrate. As will be seen from the following description, the microfluidic structures formed with this diaphragm provide easy to manufacture and robust systems, as well readily made components such as valves and pumps.

US Patent:

20120129714, May 24, 2012

Filed:

Oct 14, 2011

Appl. No.:

13/273522

Inventors:

Gwendolyn Spizz - Ithaca NY, US
Peng Zhou - Newtown PA, US

Assignee:

RHEONIX, INC. - Ithaca NY

International Classification:

C12Q 1/68
C12M 1/40
C40B 40/06
C40B 30/04

US Classification:

506 9, 435 611, 4352872, 506 16

Abstract:

Methods and systems for detecting a target nucleic acid using the quantitative capabilities of real-time nucleic acid amplification systems and the multiplexing capabilities of hybridization systems, comprising: identifying a conservative sequence and a distinctive sequence within each target nucleic acid sequence; simultaneously amplifying the conservative region and the distinctive region; monitoring the amplification of the conservative region in real-time; identifying the distinctive region amplicon via multiplexed identification; and performing quantitative multiplexing analysis of the target by combining the real-time monitoring information with the multiplexed identification of the target nucleic acid.

US Patent:

20120214168, Aug 23, 2012

Filed:

Feb 21, 2012

Appl. No.:

13/400857

Inventors:

Lincoln C. Young - Ithaca NY, US
Peng Zhou - Newtown PA, US
Gwendolyn Spizz - Ithaca NY, US
Rubina Yasmin - Ithaca NY, US

Assignee:

RHEONIX, INC. - Ithaca NY

International Classification:

C07H 1/08
C12S 99/00
G01N 27/00
C12P 19/34
C07H 21/04
C07H 21/02

US Classification:

435 612, 536 2541, 435 912, 435280

Abstract:

A method is provided for purifying nucleic acid from a sample in a microfluidic device. The method can be used to purify nucleic acids from any source known in the art that comprises nucleic acids, such as prokaryotic or eukaryotic organisms, viruses, cell, tissues, organs, etc. In a specific example, the tissue is whole blood. The method for purifying nucleic acid may run fully automated in the microfluidic device.