Raymond T Hebert

US Patent:

6369893, Apr 9, 2002

Filed:

May 19, 1999

Appl. No.:

09/314605

Inventors:

Lee A. Christel - Palo Alto CA
M. Allen Northrup - Berkeley CA
Kurt E. Petersen - San Jose CA
William A. McMillan - Cupertino CA
Gregory T. A. Kovacs - Stanford CA
Steven J. Young - Los Gatos CA
Ronald Chang - Redwood City CA
Douglas B. Dority - Mill Valley CA
Raymond T. Hebert - Los Gatos CA
Gregory J. Kintz - Mountain View CA

Assignee:

Cepheid - Sunnyvale CA

International Classification:

G01N 2164

US Classification:

356417, 2504581, 422 8208, 436172

Abstract:

An apparatus for thermally controlling and optically interrogating a reaction mixture includes a vessel [ ] having a chamber [ ] for holding the mixture. The apparatus also includes a heat-exchanging module [ ] having a pair of opposing thermal plates [ A, B] for receiving the vessel [ ] between them and for heating/and or cooling the mixture contained in the vessel. The module [ ] also includes optical excitation and detection assemblies [ ] positioned to optically interrogate the mixture. The excitation assembly [ ] includes multiple light sources [ ] and a set of filters for sequentially illuminating labeled analytes in the mixture with excitation beams in multiple excitation wavelength ranges. The detection assembly [ ] includes multiple detectors [ ] and a second set of filters for detecting light emitted from the chamber [ ] in multiple emission wavelength ranges. The optics assemblies [ ] thus provide a multi-channel system for detecting a plurality of different target analytes in the mixture.

US Patent:

6480174, Nov 12, 2002

Filed:

Oct 9, 1999

Appl. No.:

09/415613

Inventors:

Rick James Kaufmann - late of Los Gatos CA
Raymond T. Hebert - Los Gatos CA
James W. Pfeiffer - Los Gatos CA
Gary E. Hart - Santa Cruz CA
Loren D. Stirling - Aptos CA
Barry Wingate - San Jose CA
Roland J. Montalbo - San Jose CA
Peter K. S. Lee - San Jose CA

Assignee:

Optimize Incorporated - Los Gatos CA

International Classification:

G09G 500

US Classification:

345 8, 345 7, 348 52, 348 53, 359 13

Abstract:

An eyeglass-mount display (EMD) device includes a frame, a display pod, and a personalized module removably coupled to the frame. The frame has a cross-bracket and a pair of ear pieces each coupled to an end of the cross-bracket. The display pod is mounted to the cross-bracket and includes an electronic image generator for generating an image and optics for creating a virtual image. The personalized module includes preset fitting adjustments specific to a particular user. The module may also include corrective optical lenses. The removable personalized module enables multiple users to share the same EMD frame and display pod without making numerous fitting adjustments upon donning the EMD.

US Patent:

6900777, May 31, 2005

Filed:

Jan 3, 2001

Appl. No.:

09/756648

Inventors:

Raymond T. Hebert - Los Gatos CA, US
Kevin R. Hempson - Los Gatos CA, US

Assignee:

Stryker Corporation - Kalamazoo MI

International Classification:

G09G005/00

US Classification:

345 7, 345 30, 345 8, 359618

Abstract:

A video interface linking a base station with a remote display, e. g. , a head-mounted display, converts input video signals from NTSC or PAL formats into modulated video signals containing repetitive sequences of frame times with embedded audio and control signals. Each frame time includes equal consecutive color field times. Frame rates are converted by inserting selected repeating color frames into the datastream. Bursts of image information occupy a portion of each field time. During each data burst, the display is loaded with pixel luminance data. Between bursts, the display is illuminated by a color LED. Two video displays can be driven alternately, i. e. , the first display loads while the second is illuminated. The modulated video signal can travel through the atmosphere on an infrared (IR) beam with a wavelength between 700 nm and 1100 nm. In one embodiment, the beam is scattered from a diffuse reflecting surface.

US Patent:

6940598, Sep 6, 2005

Filed:

Apr 8, 2002

Appl. No.:

10/119228

Inventors:

Lee A. Christel - Palo Alto CA, US
M. Allen Northrup - Berkeley CA, US
Kurt E. Petersen - Santa Clara CA, US
William A. McMillan - Cupertino CA, US
Gregory T. A. Kovacs - Stanford CA, US
Steven J. Young - Los Gatos CA, US
Ronald Chang - Redwood City CA, US
Douglas B. Dority - Mill Valley CA, US
Raymond T. Hebert - Los Gatos CA, US
Gregory J. Kintz - Mountain View CA, US

Assignee:

Cepheid - Sunnyvale CA

International Classification:

G01N021/64

US Classification:

356417, 2504581, 422 8208, 436172

Abstract:

An apparatus for thermally controlling and optically interrogating a reaction mixture includes a vessel [] having a chamber [] for holding the mixture. The apparatus also includes a heat-exchanging module [] having a pair of opposing thermal plates [A, B] for receiving the vessel [] between them and for heating/and or cooling the mixture contained in the vessel. The module [] also includes optical excitation and detection assemblies [] positioned to optically interrogate the mixture. The excitation assembly [] includes multiple light sources [] and a set of filters for sequentially illuminating labeled analytes in the mixture with excitation beams in multiple excitation wavelength ranges. The detection assembly [] includes multiple detectors [] and a second set of filters for detecting light emitted from the chamber [] in multiple emission wavelength ranges. The optics assemblies [] thus provide a multi-channel system for detecting a plurality of different target analytes in the mixture.

US Patent:

6972735, Dec 6, 2005

Filed:

Mar 18, 2003

Appl. No.:

10/392494

Inventors:

Raymond Hebert - Los Gatos CA, US

International Classification:

G09G005/00

US Classification:

345 8, 359630

Abstract:

The present invention provides a head-mounted display system that is compact and provides a wide field of view yet reduces or eliminates eyestrain. The system includes a binocular on-axis objective lens assembly that relays an image from a display device through a split-field exit aperture onto binocular optical paths. Intermediate image planes are formed within each optical path with each intermediate image plane having an associated microstructure that enhances the exit pupil of each left and right optical path.

US Patent:

7002688, Feb 21, 2006

Filed:

Jun 9, 2004

Appl. No.:

10/865100

Inventors:

Alexander M. Aravanis - Palo Alto CA, US
Raymond T. Hebert - Los Gatos CA, US
Bryan E. Loucks - Los Altos Hills CA, US
John D. Lytle - Santa Cruz CA, US
Jason L. Pyle - Palo Alto CA, US

Assignee:

Pria Diagnostics, Inc. - Menlo Park CA

International Classification:

G01N 21/64

US Classification:

356417, 2504581

Abstract:

A diagnostics apparatus for detecting fluorescence events related to the presence of an analyte in a sample is disclosed. The apparatus includes a housing, a source of excitation light and a photodetector, and a unitary multi-surface optical module. The optical module is integrally formed and composed of an upstream portion having a focusing optical surface for directing excitation light from the light source to a focal region within an analyte-detection zone in the apparatus, and a downstream portion having a second focusing powered optical surface and at least one reflecting surface for directing fluorescence-emission light produced by fluorescence events within the detection zone, in a direction substantially normal to the path of the excitation light onto the photodetector. The optical module is adaptable to a variety of assay formats, including multiple-sample, sample-array, and disposable-cartridge formats.

US Patent:

7492461, Feb 17, 2009

Filed:

Jul 21, 2005

Appl. No.:

11/188079

Inventors:

Raymond T. Hebert - Los Gatos CA, US
Joel M. Blatt - Palo Alto CA, US
Joseph T. Widunas - Fremont CA, US

International Classification:

G01N 21/47

US Classification:

356446, 422 58

Abstract:

The present invention provides an optics assembly, a reflectometer, and a diagnostic device for providing quantitative measurement of optical radiation reflected from a sampling area on an assay matrix. The reflectometer includes an optical radiation source and a detector. The optical radiation source and the detector are mounted in a single plane. An optics assembly is configured to direct the illumination from the optical radiation source to the sampling area on the assay matrix and to direct the radiation diffusely reflected from the sampling area to the detector. The optics assembly is positioned over the face of the circuit board having the optical radiation source and detector mounted directly thereto. The present invention also provides a method for determining the presence of one or more selected analytes in a sample employing a plurality of sampling areas on one or more assay matrixes.

US Patent:

8045169, Oct 25, 2011

Filed:

Sep 22, 2008

Appl. No.:

12/235371

Inventors:

Raymond T. Hebert - Los Gatos CA, US
Joel M. Blatt - Palo Alto CA, US
Joseph T. Widunas - Fremont CA, US

Assignee:

Bayer HealthCare LLC - Tarrytown NY

International Classification:

G01N 21/55

US Classification:

356445, 356448

Abstract:

The present invention provides an optics assembly, a reflectometer, and a diagnostic device for providing quantitative measurement of optical radiation reflected from a sampling area on an assay matrix. The reflectometer includes an optical radiation source and a detector. The optical radiation source and the detector are mounted in a single plane. An optics assembly is configured to direct the illumination from the optical radiation source to the sampling area on the assay matrix and to direct the radiation diffusely reflected from the sampling area to the detector. The optics assembly is positioned over the face of the circuit board having the optical radiation source and detector mounted directly thereto. The present invention also provides a method for determining the presence of one or more selected analytes in a sample employing a plurality of sampling areas on one or more assay matrixes.