- Thousand Oaks CA, US - Munich, DE Julie Bailis - Thousand Oaks CA, US Christoph Dahlhoff - Munich, DE Sandra Ross - Thousand Oaks CA, US Irwin Chen - Thousand Oaks CA, US Claudia Blümel - Munich, DE Elisabeth Nahrwold - Munich, DE Jochen Pendzialek - Munich, DE Joachim Wahl - Munich, DE
International Classification:
C07K 16/28 C07K 16/30 A61P 35/00 A61K 9/00
Abstract:
The present invention provides bispecific antibody constructs characterized by comprising a first domain binding to MUC17, a second domain binding to an extracellular epitope of the human and the CD3E chain and optionally a third domain, which is a specific Fc modality. Moreover, the invention provides a polynucleotide, encoding the antibody construct, a vector comprising this polynucleotide, host cells, expressing the construct and a pharmaceutical composition comprising the same.
- Munich, DE - Thousand Oaks CA, US Johannes Brozy - Munich, DE Tobias Raum - Munich, DE Elisabeth Nahrwold - Munich, DE Tara Arvedson - Thousand Oaks CA, US Irwin Chen - Thousand Oaks CA, US Sandra Ross - Thousand Oaks CA, US Julie Bailis - Thousand Oaks CA, US
International Classification:
C07K 16/28 A61P 35/00
Abstract:
The present invention relates to an antibody construct comprising a domain which binds to Claudin 18.2 (CLDN18.2) and another domain which binds to CD3. Moreover, the invention provides a polynucleotide encoding the antibody construct, a vector comprising said polynucleotide and a host cell transformed or transfected with said polynucleotide or vector. Furthermore, the invention provides a process for producing the antibody construct of the invention, a medical use of said antibody construct and a kit comprising said antibody construct.
Rockwall Aesthetic Center Rockwall, TX 2006 to 2011Pediatric Dentistry Dallas, TX 1998 to 2005 DentistGeneral Dentistry Rockwall, TX 1998 to 2000US Army Dentac
1986 to 1989 Captain
Education:
University of Colorado Health Sciences Center Denver, CO 1979 to 1985 DDSUniversity of Colorado 1973 to 1978 Bachelor of Science
McKinley Elementary School St. Charles MO 1961-1964, Lincoln Elementary School St. Charles MO 1964-1968, West Junior High School Belleville IL 1968-1970
Karen Blackburn (left) congratulates participants in Goaldiggers Toastmasters impromptu speaking contest (from left) James Larsen, Patrick MacFarlane, John News, runner-up Greg Wilson, Jim Crawford, Sandra Ross and winner Adam Smith. ...