Tuan A Do

US Patent:

20210031196, Feb 4, 2021

Filed:

Oct 16, 2020

Appl. No.:

17/072332

Inventors:

- San Diego CA, US
Austin DERFUS - Solana Beach CA, US
Armando TOVAR - San Diego CA, US
Justin DAVIDSON - San Diego CA, US
Tuan DO - San Diego CA, US
Paul CRIVELLI - San Diego CA, US
Matthew WANG - San Diego CA, US

International Classification:

B01L 3/00
G01N 33/49
G01N 33/543
G01N 33/68

Abstract:

A combination of components in a capillary flow channel use capillary forces to passively control the movement of liquid samples within a microfluidic device. To detect a target, a liquid sample introduced to a proximal portion of capillary channel of a microfluidic device moves by capillary action along the specific components of capillary channel.

US Patent:

20190064158, Feb 28, 2019

Filed:

Oct 24, 2018

Appl. No.:

16/169738

Inventors:

- San Diego CA, US
Paul Michael CRIVELLI - San Diego CA, US
Austin Matthew DERFUS - Carlsbad CA, US
Tuan Hoang DO - San Diego CA, US
Remus Anders Brix HAUPT - Encinitas CA, US
Emily PARKER - Encinitas CA, US
Gregory RENEFF - San Diego CA, US
Armando Raul TOVAR - San Diego CA, US

International Classification:

G01N 33/543

Abstract:

A combination of capillary forces and gas pressure is used to control the movement of liquid samples within a microfluidic device. A liquid sample introduced to a proximal portion of a capillary channel of a microfluidic device moves by capillary action partway along the capillary channel. As the liquid sample moves, a pressure of a gas acting upon a distal gas-liquid interface of the liquid sample increases by an amount sufficient to stop further movement of the liquid sample. To initiate further movement of the liquid sample, a pump connected to a distal portion of the capillary channel decreases the pressure of the gas acting upon the distal gas-liquid interface of the liquid sample by an amount sufficient to permit the liquid sample to move by capillary action further along the capillary channel of the microfluidic device.

US Patent:

20150087079, Mar 26, 2015

Filed:

Apr 5, 2013

Appl. No.:

14/391643

Inventors:

- San Diego CA, US
Paul Michael Crivelli - San Diego CA, US
Austin Matthew Derfus - Carlsbad CA, US
Tuan Hoang Do - San Diego CA, US
Remus Anders Brix Haupt - Encinitas CA, US
Emily Parker - Encinitas CA, US
Gregory Reneff - San Diego CA, US
Armando Raul Tovar - San Diego CA, US

International Classification:

G01N 33/543

US Classification:

436501

Abstract:

A combination of capillary forces and gas pressure is used to control the movement of liquid samples within a microfluidic device. A liquid sample introduced to a proximal portion of a capillary channel of a microfluidic device moves by capillary action partway along the capillary channel. As the liquid sample moves, a pressure of a gas acting upon a distal gas-liquid interface of the liquid sample increases by an amount sufficient to stop further movement of the liquid sample. To initiate further movement of the liquid sample, a pump connected to a distal portion of the capillary channel decreases the pressure of the gas acting upon the distal gas-liquid interface of the liquid sample by an amount sufficient to permit the liquid sample to move by capillary action further along the capillary channel of the microfluidic device.