Wei Wei Ding

US Patent:

20080154567, Jun 26, 2008

Filed:

Dec 19, 2007

Appl. No.:

11/959536

Inventors:

Ping Qiu - Edison NJ, US
Jonathan Richard Greene - South Orange NJ, US
Wei Ding - Scotch Plains NJ, US
Qing Zhang - Short Hills NJ, US

International Classification:

G06G 7/58

US Classification:

703 11

Abstract:

The present invention relates to a method for developing algorithms that are capable of discriminating among different genotypes and subtypes of a virus of interest. The method includes aligning a set of viral nucleotide sequences having known genotypes and analyzing the aligned sequences to identify nucleotide positions at which the nucleotide is conserved within genotypes, but diversified across the different known genotypes. These positions, referred to herein as genotyping positions, are employed as predictive variables to compile a variable input table for analysis by a statistical classification algorithm. The variable input table also includes the nucleotide present at each genotyping position as a value and the genotype for each of the aligned sequences as a response variable. The algorithm analyzes the sequences of nucleotides at the genotyping positions across the aligned viral sequences, and uses the results of this analysis to specify parameters for each genotyping position that when combined across the genotyping positions will discriminate among the genotypes represented in the input sequences. The algorithm generated by this method is useful in a method of predicting the genotype of a viral isolate of interest, such as a virus present in a biological sample obtained from an individual.

US Patent:

20110091524, Apr 21, 2011

Filed:

Dec 17, 2008

Appl. No.:

12/808270

Inventors:

Yan Wang - Warren NJ, US
Yaolin Wang - Short Hills NJ, US
Diene Levitan - Tenafly NJ, US
Ming Liu - Fanwood NJ, US
Wei Ding - Scotch Plains NJ, US

International Classification:

A61K 39/395
C12Q 1/68
A61K 38/20
A61K 38/21
A61K 9/127
A61P 35/00
A61P 35/02
G06Q 90/00

US Classification:

424450, 435 6, 4241721, 4241751, 4241581, 4241421, 4241331, 424 852, 424 857, 705500

Abstract:

The present invention provides, for example, methods for conveniently determining if a cancerous condition in a subject will be responsive to an IGF1R inhibitor. The invention includes patient selection methods and methods of treatment.

US Patent:

20220404603, Dec 22, 2022

Filed:

Nov 9, 2020

Appl. No.:

17/775577

Inventors:

- Monmouth Junction NJ, US
Stephen Y. CHOU - Princeton NJ, US
Wu CHOU - Basking Ridge NJ, US
Wei DING - Princeton NJ, US

Assignee:

Essenlix Corporation - Monmouth Junction NJ

International Classification:

G02B 21/36
G02B 21/26

Abstract:

A microscopy imaging system and methods for improving an assaying of a sample is disclosed.

US Patent:

20220407988, Dec 22, 2022

Filed:

Aug 26, 2022

Appl. No.:

17/896973

Inventors:

- Monmouth Junction NJ, US
Wei Ding - East Windsor NJ, US
Yufan Zhang - Monmouth Junction NJ, US
Ji Qi - Hillsborough NJ, US
Jun Tian - Belle Mead NJ, US
Wei Dong - Monmouth Junction NJ, US

Assignee:

Essenlix Corporation - Monmouth Junction NJ

International Classification:

H04N 5/225
G01N 21/84

Abstract:

The present disclosure relates to devices, apparatus and methods of improving the accuracy of an image-based assay. One aspect of the present invention is to sandwich a sample between two plates and add reference marks in the sample areas of the plates, with at least one of the geometric and/optical properties of the reference marks being predetermined and known, and taking images of the sample with the reference marks, and applying a machine learning model in the analysis of the image-based assay.

US Patent:

20220357271, Nov 10, 2022

Filed:

Jun 22, 2020

Appl. No.:

17/621216

Inventors:

- Monmouth Junction NJ, US
Wei DING - Princeton NJ, US
Ji QI - Hillsborough NJ, US
Jun TIAN - Belle Mead NJ, US
Wu CHOU - Basking Ridge NJ, US
Hongbing LI - Skillman NJ, US

Assignee:

Essenlix Corporation - Monmouth Junction NJ

International Classification:

G01N 21/31
G01N 21/03

Abstract:

The disclosure provides an apparatus, a device, and methods for improving optical analysis of a thin layer of a sample between two plates, particularly for multiple wavelengths.

US Patent:

20220341842, Oct 27, 2022

Filed:

Jul 6, 2022

Appl. No.:

17/858931

Inventors:

- Monmouth Junction NJ, US
Wei DING - East Windsor NJ, US
Ji QI - Skillman NJ, US
Jun Tian - Belle Mead NJ, US
Wu Chou - Basking Ridge NJ, US

Assignee:

Essenlix Corporation - Monmouth Junction NJ

International Classification:

G01N 21/03
G01N 1/28
G01N 21/25
G01N 21/64
G01N 33/49

Abstract:

Among other things, the present invention is related to devices and methods for improving optical analysis of a thin layer of a sample sandwiched between containing between two plates.

US Patent:

20220299422, Sep 22, 2022

Filed:

Dec 29, 2021

Appl. No.:

17/565115

Inventors:

- Monmouth Junction NJ, US
Wei DING - Princeton NJ, US
Wu CHOU - Basking Ridge NJ, US
Jun TIAN - Belle Mead NJ, US
Yuecheng ZHANG - Yardley PA, US
Mingquan WU - Princeton Junction NJ, US
Xing LI - Metuchen NJ, US

Assignee:

Essenlix Corporation - Monmouth Junction NJ

International Classification:

G01N 15/14
G06N 20/00
G01N 1/28
G06N 3/08
G06T 1/00

Abstract:

The present invention is related to correct the errors in instruments, operation, and others using intelligent monitoring structures and machine learning, and others.

US Patent:

20220291093, Sep 15, 2022

Filed:

May 24, 2022

Appl. No.:

17/752823

Inventors:

- Monmouth Junction NJ, US
Wei DING - East Windsor NJ, US

Assignee:

Essenlix Corporation - Monmouth Junction NJ

International Classification:

G01N 1/28
G01N 33/49
G01N 21/64
G01N 1/30
G01N 15/14
G01N 21/69
G01N 21/76
G01N 33/543
B01L 3/00
G01N 33/487
G01N 35/00

Abstract:

The present invention is related to the field of bio/chemical sampling, sensing, assays and applications. Particularly, the present invention is related to how to make the sampling/sensing/assay become simple to use, fast to results, highly sensitive, easy to use, using tiny sample volume (e.g. 0.5 uL or less), operated by a person without any professionals, reading by mobile-phone, or low cost, or a combination of them.