The present invention relates to chemical compounds, methods for their discovery, and their therapeutic use. In particular, the present invention provides compounds as inhibitors of alphaviruses.
Compositions And Methods For Treating Mdma-Induced Toxicity
Rabi Simantov - Rehovot, IL Weiping Peng - Lincoln NE, US
Assignee:
YEDA RESEARCH AND DEVELOPMENT CO. LTD. - Rehovot
International Classification:
A61K031/704
US Classification:
514026000
Abstract:
This invention relates to methods and compositions for treating or preventing the symptoms associated with toxicity induced by ingestion of MDMA. In one aspect, the present invention is related to methods for treating or preventing the symptoms associated with MDMA, or MDMA-related psychoactive drugs by administering to a subject in need thereof a composition that includes a therapeutically effective amount of an agent which inhibits γ-amino butyric acid (GABA) transporter activity or reduces GABA transporter level in the brain.