Amy A Nguyen

US Patent:

20050238675, Oct 27, 2005

Filed:

Apr 19, 2005

Appl. No.:

11/109548

Inventors:

Wenjie Li - Ladera Ranch CA, US
Amy Nguyen - Newport Beach CA, US
Edward Alosio - Coto De Caza CA, US
Bricini Dema-Ala - Aliso Viejo CA, US

International Classification:

A61K031/57
A61K031/355
A61K031/22

US Classification:

424400000, 514546000, 514458000, 514560000, 514171000

Abstract:

Aqueous liquid or gel formulations of fat soluble vitamins, essential nutrients and other pharmaceutical agents have enhanced concentration of the active components relative to known compositions and therefore have enhanced bioavailability. The aqueous solutions or gels form a free flowing powder when they are absorbed on a suitable pharmaceutically acceptable solid carrier, such as silicon dioxide, maltodextrin, magnesium oxide, aluminum hydroxide, magnesium trisilicate, starch or sugars, or encapsulated by polymers such as gelatin, pectin, chitosan and the like.

US Patent:

20060263397, Nov 23, 2006

Filed:

Jul 27, 2006

Appl. No.:

11/494131

Inventors:

Wenji Li - Aliso Viejo CA, US
Edward Alosio - Coto De Caza CA, US
Bricini Dema-Ala - Aliso Viejo CA, US
Amy Nguyen - Newport Beach CA, US

International Classification:

A61K 9/00
A61K 9/20

US Classification:

424400000, 424464000

Abstract:

A free-flowing solid formulations of drugs or pharmaceutical agents which have poor aqueous solubility are obtained by admixing a liquid or gel composition that includes 1 to 30 per cent by weight of the drug, 5 to 60 per cent by weight of a surfactant, 10 to 40 per cent by weight of water; 1 to 20 per cent by weight of unsaturated fatty acid ester, 0 to 50 per cent by weight water miscible pharmaceutically acceptable polyol and 1 to 10 per cent by weight of phospholipid with a pharmaceutically acceptable suitable solid carrier and thereafter drying the admixture. The free-flowing powder is suitable for being formed into tablets or capsules. The drug or pharmaceutical agent is solubilized in the formulation and has significantly improved bio-availability when compared to the drug tested in its pure form.

US Patent:

20070009559, Jan 11, 2007

Filed:

Jul 27, 2006

Appl. No.:

11/494129

Inventors:

Wenji Li - Aliso Viejo CA, US
Edward Alosio - Coto De Caza CA, US
Bricini Dema-Ala - Aliso Viejo CA, US
Amy Nguyen - Newport Beach CA, US

International Classification:

A61K 9/00

US Classification:

424400000

Abstract:

A free-flowing solid formulations of drugs or pharmaceutical agents which have poor aqueous solubility are obtained by admixing a liquid or gel composition that includes 1 to 30 percent by weight of the drug, 5 to 60 percent by weight of a surfactant, 10 to 40 percent by weight of water; 1 to 20 percent by weight of unsaturated fatty acid ester, 0 to 50 percent by weight water miscible pharmaceutically acceptable polyol and 1 to 10 percent by weight of phospholipid with a pharmaceutically acceptable suitable solid carrier and thereafter drying the admixture. The free-flowing powder is suitable for being formed into tablets or capsules. The drug or pharmaceutical agent is solubilized in the formulation and has significantly improved bio-availability when compared to the drug tested in its pure form.

US Patent:

20040115226, Jun 17, 2004

Filed:

Dec 12, 2002

Appl. No.:

10/317657

Inventors:

Wenji Li - Aliso Viejo CA, US
Edward Alosio - Coto De Caza CA, US
Bricini Dema-Ala - Aliso Viejo CA, US
Amy Nguyen - Newport Beach CA, US

International Classification:

A61K009/00
A61K009/127

US Classification:

424/400000, 424/450000

Abstract:

A free-flowing solid formulations of drugs or pharmaceutical agents which have poor aqueous solubility are obtained by admixing a liquid or gel composition that includes 1 to 30 per cent by weight of the drug, 5 to 60 per cent by weight of a surfactant, 10 to 40 per cent by weight of water; 1 to 20 per cent by weight of unsaturated fatty acid ester, 0 to 50 per cent by weight water miscible pharmaceutically acceptable polyol and 1 to 10 per cent by weight of phospholipid with a pharmaceutically acceptable suitable solid carrier and thereafter drying the admixture. The free-flowing powder is suitable for being formed into tablets or capsules. The drug or pharmaceutical agent is solubilized in the formulation and has significantly improved bio-availability when compared to the drug tested in its pure form.