Yin Liang

US Patent:

20040005299, Jan 8, 2004

Filed:

Mar 21, 2003

Appl. No.:

10/394902

Inventors:

Yin Liang - Bridgewater NJ, US
Jian Zhu - North Haven CT, US
Laurel Sweet - Branford CT, US
James Livingston - Guilford CT, US

Assignee:

Bayer Pharmaceuticals Corporation - West Haven CT

International Classification:

A61K045/00
C12N005/08

US Classification:

424/093700, 435/366000

Abstract:

The present invention relates to a method for preparing pseudo islets. In addition, the invention is also directed to methods of treating diabetes and diabetes-related disorders by administering compounds identified by the methods described herein.

US Patent:

20110065200, Mar 17, 2011

Filed:

Sep 14, 2010

Appl. No.:

12/881695

Inventors:

Keith T. Demarest - Flemington NJ, US
James M. Lenhard - Fort Washington PA, US
Gregory C. Leo - Lansdale PA, US
Yin Liang - Owings Mills MD, US
Tonya L. Martin - Quakertown PA, US

Assignee:

Janssen Pharmaceutica, N.V. - Beerse

International Classification:

G01N 33/50

US Classification:

436 93

Abstract:

Presented here are methods using alpha-methylglucoside (AMG) in vivo as an indicator for glucose absorption from the gastrointestinal (GI) system or glucose excretion in the urine after oral administration of AMG. The methods find use in, for example, but not limited to, determining the effect of a sodium-dependent glucose transporter (SGLT) inhibitor in an animal, comparing the differences in the effects of a first and second SGLT inhibitor in an animal, and diagnosing a disease associated with glucose absorption from the gastrointestinal (GI) system or glucose excretion from the kidney in an animal.

Address:

147 Cornell St, Roslindale, MA 02131

VIN:

4T3BK3BB6AU030359

Make:

TOYOTA

Model:

VENZA

Year:

2010