Ying Jiang

US Patent:

6339130, Jan 15, 2002

Filed:

Mar 31, 1999

Appl. No.:

09/282724

Inventors:

Steven L. Bennett - Watertown CT
Kevin Connolly - Culver City CA
Elliott Gruskin - Killingsworth CT
Ying Jiang - North Haven CT

Assignee:

United States Surgical Corporation - Norwalk CT

International Classification:

A61L 2404

US Classification:

525415, 528 73, 528 81

Abstract:

Star polymers of soft segment forming monomers are useful in forming surgical devices. The star polymers can be endcapped with isocyanate, mixed with a filler and/or cross-linked. The polymer compositions are useful, for example, as fiber coatings, surgical adhesives or bone putty, or tissue growth substrate.

US Patent:

7097907, Aug 29, 2006

Filed:

Jul 30, 2003

Appl. No.:

10/630945

Inventors:

Steven L. Bennett - Watertown CT, US
Kevin Connolly - Culver City CA, US
Elliott Gruskin - Killingworth CT, US
Ying Jiang - North Haven CT, US

Assignee:

United States Surgical Corporation - North Haven CT

International Classification:

A61L 31/10
C09D 167/04

US Classification:

4284231, 525415, 528 73, 528 81, 602 41, 606 76, 606 77, 623 2211, 623 2359

Abstract:

Star polymers of soft segment forming monomers are useful in forming surgical devices. The star polymers can be endcapped with isocyanate, mixed with a filler and/or cross-linked. The polymer compositions are useful, for example, as fiber coatings, surgical adhesives or bone putty, or tissue growth substrate.

US Patent:

7321008, Jan 22, 2008

Filed:

Aug 28, 2006

Appl. No.:

11/511133

Inventors:

Steven L. Bennett - Watertown CT, US
Kevin Connolly - Culver City CA, US
Elliott Gruskin - Killingworth CT, US
Ying Jiang - North Haven CT, US

Assignee:

United States Surgical Corporation - North Haven CT

International Classification:

C08L 65/26
C08L 65/331
A61L 31/06

US Classification:

524 54, 528297, 528365, 528366, 528370, 528393, 525412, 606 77, 606230

Abstract:

Star polymers of soft segment forming monomers are useful in forming surgical devices. The star polymers can be endcapped with diketene acetals, mixed with a filler and/or cross-linked. The polymer compositions are useful, for example, as fiber coatings, surgical adhesives or bone putty, or tissue growth substrate.

US Patent:

20020032298, Mar 14, 2002

Filed:

Aug 22, 2001

Appl. No.:

09/934639

Inventors:

Steven Bennett - Watertown CT, US
Kevin Connolly - Culver City CA, US
Elliott Gruskin - Killingsworth CT, US
Ying Jiang - North Haven CT, US

International Classification:

C08G018/10

US Classification:

528/059000

Abstract:

Star polymers of soft segment forming monomers are useful in forming surgical devices. The star polymers can be endcapped with isocyanate, mixed with a filler and/or cross-linked. The polymer compositions are useful, for example, as fiber coatings, surgical adhesives or bone putty, or tissue growth substrate.

US Patent:

20040253647, Dec 16, 2004

Filed:

Aug 6, 2004

Appl. No.:

10/481954

Inventors:

Paul Mathews - Irvington-on-Hudson NY, US
Ralph Nixon - Tarrytown NY, US
Stephen Schmidt - Nutley NJ, US
Ying Jiang - Valhalla NY, US

International Classification:

G01N033/53
G01N033/567

US Classification:

435/007200

Abstract:

The present invention describes cell-based screening methods that allow for the elimination of false-positive results due to nonspecific toxicity of test compounds, while detecting those compounds that specifically modulate cellular metabolites in metabolic pathways associated with diseases and disorders, with particular regard to Alzheimer's disease. The methods are particularly suited to high-throughput screening techniques to identify compounds (drugs) that are effective in a cell-based system. The methods of the invention involve determining within a cell system the levels of both a metabolic precursor and a metabolite of interest and have broad application in high-throughput drug discovery and identification, particularly for precursor and metabolite molecules which are associated with disease and disease progression, such as Alzheimer's disease.

US Patent:

55059520, Apr 9, 1996

Filed:

Apr 19, 1994

Appl. No.:

8/229970

Inventors:

Ying Jiang - North Haven CT
Elliott A. Gruskin - Killingworth CT

Assignee:

United States Surgical Corporation - Norwalk CT

International Classification:

A61L 1500
A61L 3100

US Classification:

424423

Abstract:

Synthetic, cross-linked amino-acid containing polymers are useful in forming medical devices. The hydrogels of the invention are particularly useful in wound healing and anti-adhesion applications.

US Patent:

56266111, May 6, 1997

Filed:

Feb 10, 1994

Appl. No.:

8/194766

Inventors:

Cheng-Kung Liu - Norwalk CT
Ying Jiang - North Haven CT
Mark S. Roby - Killingworth CT
Steven L. Bennett - New Haven CT
Richard P. Stevenson - Colchester CT
Jeffrey P. Pietrangeli - Bridgeport CT

Assignee:

United States Surgical Corporation - Norwalk CT

International Classification:

A61B 1700

US Classification:

606230

Abstract:

The present invention relates to composite materials having a core portion formed from a first bioabsorbable material and at least one shell portion of a second bioabsorbable material joined to the core portion. The first and second bioabsorbable materials have different rates of bioabsorption. In a preferred embodiment, the core portion is coextruded with the shell portion to form a composite filament or sheet. The materials of the present invention may be used as sutures or formed into medical devices or surgical articles for implantation within a living organism.

US Patent:

62077678, Mar 27, 2001

Filed:

Nov 26, 1997

Appl. No.:

8/979009

Inventors:

Steven L. Bennett - New Haven CT
Ying Jiang - North Haven CT
Elliott A. Gruskin - Killingsworth CT
Kevin M. Connolly - Hamden CT

Assignee:

United States Surgical Corporation - Norwalk CT

International Classification:

C08G64/02;63/06
7
A61L24/04
31/06

US Classification:

525415

Abstract:

Star polymers of soft segment forming monomers are useful in forming surgical devices. The star polymers can be encapped with isocyanate, mixed with a filler and/or cross-linked. The polymer compositions are useful, for example, as fiber coatings, surgical adhesives or bone putty, or tissue growth substrate.