An embodiment of the invention provides preventing or treating a viral infection of a host, comprising administering to the host an effective amount of an inhibitor of the protein LSD1 and/or a monoamine oxidase inhibitor. Another embodiment of the invention provides preventing or treating reactivation of a virus after latency in a host, comprising administering to the host an effective amount of an inhibitor of the protein LSD1 and/or a monoamine oxidase inhibitor. Another embodiment of the invention provides preventing or treating a viral infection in a mammal that has undergone, is undergoing, or will undergo an organ or tissue transplant, comprising administering to the mammal an effective amount of an inhibitor of the protein LSD1 and/or a monoamine oxidase inhibitor before, during, and/or after the organ or tissue transplant. The viral infection may be due to a herpesvirus, such as herpes simplex virus type 1 (HSV-1) or type 2 (HSV-2), varicella zoster virus (VZV), or cytomegalovirus (CMV). The viral infection may also be due to an adenovirus, including types 1-5.
The United States of America, as Represented by the Secretary, Department of Health and Human Services - Bethesda MD, US Yu Liang - Gaithersburg MD, US Jodi Vogel - Bethesda MD, US David J. Maloney - Point of Rocks MD, US Anton Simeonov - Bethesda MD, US Ajit Jadhav - Chantilly VA, US
Assignee:
The United States of America, as represented by the Secretary, Dept. of Health and Human Services - Bethesda MD
Disclosed are compounds and pharmaceutical compositions containing compounds that inhibit JMJD2 proteins, including those of the formula (I):wherein R, R, R, R, and Rare as defined herein or pharmaceutically acceptable salts thereof. Also disclosed is a method of preventing or treating a viral infection of a host, comprising administering to the host an effective amount of an inhibitor of the JMJD2 family of histone demethylases, for example, a compound of the formula (I). The viral infection may be a primary infection, reactivation of a virus after latency in a host, or may be in a mammal that has undergone, is undergoing, or will undergo immunosuppressive therapy.
The invention relates to a polymer thick film (PTF) conductive paste composition comprising a conductive powder, a fluoroelastomer, a silane coupling agent, and one or solvents. The PTF conductive paste composition can be used to form a printed conductor and to form an electrically conductive adhesive on various articles. The PTF conductive paste composition is provides a stretchable electrical conductor for wearables.
Preventing Or Treating Viral Infection Using An Inhibitor Of The
Lsd1 Protein, A Mao Inhibitor Or An Inhibitor Of Lsd1 And A Mao
Inhibitor
- Bethesda MD, US Yu Liang - Rockville MD, US Jodi Vogel - Bethesda MD, US
International Classification:
C12N 15/113
US Classification:
514 44 A
Abstract:
An embodiment of the invention provides a method of preventing or treating a viral infection of a host, comprising administering to the host an effective amount of an inhibitor of the protein LSD1 and/or a monoamine oxidase inhibitor. Another embodiment of the invention provides a method of preventing or treating reactivation of a virus after latency in a host, comprising administering to the host an effective amount of an inhibitor of the protein LSD1 and/or a monoamine oxidase inhibitor. Another embodiment of the invention provides a method of preventing or treating a viral infection in a mammal that has undergone, is undergoing, or will undergo an organ or tissue transplant, comprising administering to the mammal an effective amount of an inhibitor of the protein LSD1 and/or a monoamine oxidase inhibitor before, during, and/or after the organ or tissue transplant. The viral infection may be due to a herpesvirus, such as herpes simplex virus type 1 (HSV-1) or type 2 (HSV-2), varicella zoster virus (VZV), or cytomegalovirus (CMV). The viral infection may also be due to an adenovirus, including types 1-5.
Wikipedia References
Yu Liang
Work:
Position:
Minister • Governor
Education:
Area of science:
Rhetoric
Skills & Activities:
Preference:
Treason
Military rank:
Commander
Master status:
Empress
Skill:
Empress
Name / Title
Company / Classification
Phones & Addresses
Yu Hua Liang President
America International Genetics and Breeding Co., Ltd
National Institutes of Health Feb 2006 - Sep 2012
Research Fellow
Novartis Feb 2006 - Sep 2012
Investigator Ii
The University of Chicago Sep 1998 - Jan 2006
Doctoral Research and Post-Doctoral Scholar
Inst of Virology Chinese Academy of Preventive Medicine Sep 1992 - Jul 1998
Research Assistant and Masterâ S Research
Education:
University of Chicago 1998 - 2005
Doctorates, Doctor of Philosophy, Microbiology, Virology
Chinese Academy of Preventive Medicine
Master of Science, Masters, Microbiology, Immunology
Wuhan University
Bachelors, Bachelor of Science, Biology
Skills:
Molecular Biology Protein Expression Cell Based Assays Infectious Diseases Rt Pcr Drug Discovery Vaccine Development Chromatin Biology Gene Delivery Tissue Culture Biotechnology Gene Therapy Virology Flow Cytometry Life Sciences Vaccines Cell Assay Development Qpcr Immunology Molecular Cloning Lifesciences Elisa Antibodies Protein Purification Protein Chemistry Cell Biology Glp Biochemistry Western Blotting Cell Culture Pcr Animal Models
Digital Systems since 2012
Statistician
Research assistant Jun 2011 - 2011
Research assistant
People's Insurance Company of China - People's Insurance Company of China Jun 2009 - Sep 2009
Intern
Haitai Company LTD - Haitai Company LTD., China Jun 2008 - Sep 2008
Manager Assistant
Education:
Georgetown University 2010 - 2012
Master of Science (M.Sc.), Mathematics and Statistics
Georgetown University 2010 - 2012
Master of Science, Math and Statistics
Tianjin University of Finance and Economics 2006 - 2010
Bachelor of Science, Applied Mathematics
Operations Manager, International Center for Communication Development at Internews Network
Location:
Beijing City, China
Industry:
Nonprofit Organization Management
Work:
Internews Network - Beijing, China since Sep 2009
Operations Manager, International Center for Communication Development
Sun Media Investment Holdings - Shanghai, China Mar 2005 - Jan 2006
Commercial Assistant to Chairman
Observer Star - Shanghai, China Aug 2004 - Mar 2005
International Business Editor
China Daily - Shanghai, China Mar 2000 - Aug 2004
Reporter
Education:
Ohio University 2006 - 2009
M.S. in Journalism, M.A. in Communication and Development Studies, Journalism; Communication & Development Studies
Skills:
Journalism
Interests:
new media technology, music
Honor & Awards:
In May 2009, “Collision of Cultures”, a co-authored two-day news series published in Columbus Dispatch, Dayton Daily News, and Springfield News-Sun won the First place award in the 2008 Associated Press Society of Ohio competition (Best Enterprise Reporting category, Division V).
In addition, I contributed writing to New Media for a New China by Blackwell Publishing Ltd (2010) and Yangtze River Ports 2006 by Alain Charles Publishing Ltd (2006).
Oct 2012 to 2000 StatisticianGeorgetown University Lombardi Cancer Center Washington, DC May 2012 to Sep 2012 Research AnalystPeople's Insurance Company of China
Jun 2009 to Sep 2009 Manager Analyst
Education:
Georgetown University Washington, DC 2010 to 2012 Master of Science in Math and StatisticsTianjin University of Finance and Economics 2006 to 2010 Bachelor of Science in Applied Mathematics
Skills:
SAS( Base/Macro ), R, Matlab, SQL, C++, Microsoft Office (MS Access, Excel, PowerPoint, Word, Outlook), Two Actuarial Exams
Youtube
Rainie YANG Cheng Lin () - Hei Se Yue Liang ()
Download MV : www.megaupload.c...
Category:
Music
Uploaded:
07 May, 2010
Duration:
3m 29s
Tui shou ma yue liang
Tui shou in a park. Original sound
Category:
Sports
Uploaded:
29 Aug, 2008
Duration:
2m 29s
Yue Liang Dai Biao De Xin - Kim Chiu
Official MV of Yue Liang Dai Biao De Xin by Kim Chiu
Category:
Entertainment
Uploaded:
24 Sep, 2007
Duration:
3m 40s
JJ Lin- Yue Liang Re De Huo
JJsinging ! With pics from MV. ...
Category:
Music
Uploaded:
28 Sep, 2007
Duration:
4m 10s
Ma Yu Liang push hands
For eF purposes...I'll be taking this down soon so get it while you can!
Category:
People & Blogs
Uploaded:
09 Jun, 2006
Duration:
4m 26s
Grandmaster Shou-Yu Liang - Xiao Yao Zhang
Grandmaster Shou-Yu Liang performing Xiao Yao Zhang at the 2009 Tiger ...
Category:
Sports
Uploaded:
20 Jul, 2009
Duration:
3m 22s
Googleplus
Yu Liang
Education:
National Cheng Kung University - Industrial Design