Yu S Liang

US Patent:

20110144184, Jun 16, 2011

Filed:

Jul 23, 2009

Appl. No.:

13/055587

Inventors:

Thomas Kristie - Silver Spring MD, US
Yu Liang - Rockville MD, US

Assignee:

The United States of America, as rep. by the Secretary, Dept of HHS - Bethesda MD

International Classification:

A61K 31/7105
A61K 31/135
A61K 31/137
A61K 31/15
A61K 31/42
A61P 31/12
A61P 31/20
A61P 31/22

US Classification:

514 44 A, 514647, 514655, 514654, 514378

Abstract:

An embodiment of the invention provides preventing or treating a viral infection of a host, comprising administering to the host an effective amount of an inhibitor of the protein LSD1 and/or a monoamine oxidase inhibitor. Another embodiment of the invention provides preventing or treating reactivation of a virus after latency in a host, comprising administering to the host an effective amount of an inhibitor of the protein LSD1 and/or a monoamine oxidase inhibitor. Another embodiment of the invention provides preventing or treating a viral infection in a mammal that has undergone, is undergoing, or will undergo an organ or tissue transplant, comprising administering to the mammal an effective amount of an inhibitor of the protein LSD1 and/or a monoamine oxidase inhibitor before, during, and/or after the organ or tissue transplant. The viral infection may be due to a herpesvirus, such as herpes simplex virus type 1 (HSV-1) or type 2 (HSV-2), varicella zoster virus (VZV), or cytomegalovirus (CMV). The viral infection may also be due to an adenovirus, including types 1-5.

US Patent:

20110171531, Jul 14, 2011

Filed:

Sep 8, 2010

Appl. No.:

12/877602

Inventors:

Mark C. Hersam - Wilmette IL, US
Gordana Ostojic - Evanston IL, US
Yu Teng Liang - Chicago IL, US

Assignee:

NORTHWESTERN UNIVERSITY - Evanston IL

International Classification:

H01M 4/583
B01J 20/28
H01L 31/0224
B82Y 30/00

US Classification:

4292318, 502 4, 136256, 977750, 977751, 977932

Abstract:

In one aspect, the present invention provides a method of forming a film of nanocomposites of carbon nanotubes (CNTs) and platinum (Pt) nanoparticles. In one embodiment, the method includes the steps of (a) providing a first solution that contains a plurality of CNTs, (b) providing a second solution that contains a plurality of Pt nanoparticles, (c) combining the first solution and the second solution to form a third solution, and (d) filtering the third solution through a nanoporous membrane using vacuum filtration to obtain a film of nanocomposites of CNTs and Pt nanoparticles.

US Patent:

20130123344, May 16, 2013

Filed:

Jan 22, 2013

Appl. No.:

13/747406

Inventors:

The United States of America, as Represented by the Secretary, Department of Health and Human Services - Bethesda MD, US
Yu Liang - Gaithersburg MD, US
Jodi Vogel - Bethesda MD, US
David J. Maloney - Point of Rocks MD, US
Anton Simeonov - Bethesda MD, US
Ajit Jadhav - Chantilly VA, US

Assignee:

The United States of America, as represented by the Secretary, Dept. of Health and Human Services - Bethesda MD

International Classification:

A61K 31/551
C07D 215/14
A61K 31/506
A61K 31/5377
A61K 31/47
A61K 31/496

US Classification:

514 44 A, 514312, 51425307, 514256, 5142352, 514218, 546170, 546174, 544363, 544333, 544128, 540575

Abstract:

Disclosed are compounds and pharmaceutical compositions containing compounds that inhibit JMJD2 proteins, including those of the formula (I):wherein R, R, R, R, and Rare as defined herein or pharmaceutically acceptable salts thereof. Also disclosed is a method of preventing or treating a viral infection of a host, comprising administering to the host an effective amount of an inhibitor of the JMJD2 family of histone demethylases, for example, a compound of the formula (I). The viral infection may be a primary infection, reactivation of a virus after latency in a host, or may be in a mammal that has undergone, is undergoing, or will undergo immunosuppressive therapy.

US Patent:

20180340090, Nov 29, 2018

Filed:

Jul 23, 2018

Appl. No.:

16/042251

Inventors:

- Evanston IL, US
Yu Teng Liang - Chicago IL, US

International Classification:

C09D 101/28
C08K 5/05

Abstract:

A rapid, scalable methodology for graphene dispersion with a polymer-organic solvent solution and subsequent solvent exchange, as can be utilized without centrifugation, to enhance graphene concentration.

US Patent:

20180187032, Jul 5, 2018

Filed:

Feb 26, 2018

Appl. No.:

15/905358

Inventors:

Mark C. Hersam - Wilmette IL, US
Yu Teng Liang - Chicago IL, US
Ethan B. Secor - Evanston IL, US
Pradyumna L. Prabhumirashi - Chicago IL, US
Kanan P. Puntambekar - Chicago IL, US
Michael L. Geier - Chicago IL, US
Bok Y. Ahn - Cambridge MA, US
Jennifer A. Lewis - Cambridge MA, US

International Classification:

C09D 11/38
C09D 11/322
B41J 2/01
B41M 5/00
C01B 32/19
C09D 11/14

Abstract:

A rapid, scalable methodology for graphene dispersion and concentration with a polymer-organic solvent medium, as can be utilized without centrifugation, to enhance graphene concentration.

US Patent:

20180094156, Apr 5, 2018

Filed:

Dec 4, 2017

Appl. No.:

15/830762

Inventors:

Mark C. Hersam - Wilmette IL, US
Yu Teng Liang - Chicago IL, US
Ethan B. Secor - Evanston IL, US
Pradyumna L. Prabhumirashi - Chicago IL, US
Kanan P. Puntambekar - Chicago IL, US
Michael L. Geier - Chicago IL, US

International Classification:

C09D 11/38
C09D 11/52
C09D 11/14
H01B 1/24

Abstract:

A rapid, scalable methodology for graphene dispersion and concentration with a polymer-organic solvent medium, as can be utilized without centrifugation, to enhance graphene concentration.

US Patent:

20180086932, Mar 29, 2018

Filed:

Dec 4, 2017

Appl. No.:

15/830508

Inventors:

Mark C. Hersam - Wilmette IL, US
Yu Teng Liang - Chicago IL, US
Ethan B. Secor - Evanston IL, US
Pradyumna L. Prabhumirashi - Chicago IL, US
Kanan P. Puntambekar - Chicago IL, US
Michael L. Geier - Chicago IL, US

International Classification:

C09D 11/38
C09D 11/52
C09D 11/14
H01B 1/24

Abstract:

A rapid, scalable methodology for graphene dispersion and concentration with a polymer-organic solvent medium, as can be utilized without centrifugation, to enhance graphene concentration.

US Patent:

20150315398, Nov 5, 2015

Filed:

Jul 13, 2015

Appl. No.:

14/797999

Inventors:

Mark C. Hersam - Wilmette IL, US
Yu Teng Liang - Chicago IL, US

International Classification:

C09D 101/28
C08K 5/05
C08K 5/20
C08K 3/04
C08K 5/3415
C08K 5/10

Abstract:

A rapid, scalable methodology for graphene dispersion with a polymer-organic solvent solution and subsequent solvent exchange, as can be utilized without centrifugation, to enhance graphene concentration.